CovidResearchTrials by Shray Alag
- drug143: CAStem Placebo (93) Hydroxychloroquine (64) Azithromycin (22) Placebo oral tablet (20) Tocilizumab (16) Placebos (14) Remdesivir (11) Hydroxychloroquine Sulfate (10) Lopinavir/ritonavir (10) Standard of Care (9) Convalescent Plasma (8) Methylprednisolone (8) No intervention (8) Standard of care (8) Anakinra (7) Losartan (7) placebo (7) Chloroquine (6) Favipiravir (6) Sarilumab (6) SnPP Protoporphyrin (6) Colchicine (5) Oseltamivir (5) Ruxolitinib (5) Vitamin C (5) Control (4) Convalescent plasma (4) DAS181 (4) Presatovir (4) Questionnaire (4) Standard care (4) Telerehabilitation (4) UC-MSCs (4) Usual Care (4) blood sampling (4) Ascorbic Acid (3) BCG Vaccine (3) Blood sample (3) COVID-19 RT-PCR (3) Camostat Mesilate (3) Control group (3) Hydrocortisone (3) Hydroxychloroquine (HCQ) (3) Interferon Beta-1A (3) Interferon Beta-1B (3) Lopinavir / Ritonavir (3) Lung ultrasound (3) Nitric Oxide Gas (3) Plasma (3) Standard treatment (3) Suspension of heat killed (autoclaved) Mycobacterium w (3) Telemedicine (3) Vitamin D (3) anti-SARS-CoV-2 convalescent plasma (3) blood sample (3) hydroxychloroquine (3) ACE inhibitor (2) Abidol hydrochloride (2) Arbidol (2) Azithromycin Tablets (2) Baricitinib (2) Bevacizumab Injection (2) Blood draw (2) COVID-19 Serology (2) ChAdOx1 MERS (2) Chloroquine Sulfate (2) Chloroquine or Hydroxychloroquine (2) Chloroquine phosphate (2) Data collection (2) Dexamethasone injection (2) Dornase Alfa Inhalation Solution [Pulmozyme] (2) Doxycycline (2) Echocardiography (2) Eculizumab (2) Follow up (2) GLS-5300 (2) HB-adMSCs (2) Hydroxychloroquine + azithromycin (2) Hydroxychloroquine - Weekly Dosing (2) Hydroxychloroquine Sulfate Loading Dose (2) Hydroxychloroquine Sulfate Regular dose (2) Hydroxychloroquine sulfate (2) Ivermectin (2) L-ascorbic acid (2) Leronlimab (700mg) (2) MSCs (2) Mesenchymal Stromal Cells (2) NORS (Nitric Oxide Releasing Solution) (2) Nasal swab (2) Nasopharyngeal swab (2) Nitazoxanide (2) Nitric Oxide (2) Nivolumab (2) No Intervention (2) Online questionnaire (2) PUL-042 Inhalation Solution (2) Povidone-Iodine Nasal Spray and Gargle (2) Prednisone (2) Prone positioning (2) Questionnaires (2) Remdesivir placebo (2) Ruxolitinib Oral Tablet (2) Selinexor (2) Siltuximab (2) Single Dose of Hydroxychloroquine (2) SivoMixx (200 billion) (2) Standard Care (2) Sulfonated tetra-anthracenyl porphyrin (2) Telmisartan (2) Tocilizumab (TCZ) (2) basic treatment (2) convalescent plasma (2) observational (2) oxygen therapy (2) pregnant women with laboratory-confirmed 2019-n-CoV (2) retrospective analysis (2) self-administered questionnaire (2) standard care (2) "Calm" is a mindfulness meditation mobile app (1) (Standard of Care) SoC (1) - Synthetic anti-malarial drugs (1) 0.9% sodium chloride (normal saline) (1) 100 mg/mL Virazole (1) 1: ILT101 (1) 1: Naproxen (1) 1: Prone positioning (1) 1: Usual practice (1) 1: discontinuation of RAS blocker therapy (1) 2019-nCoV PCR (1) 2: No instruction regarding positioning (1) 2: Placebo Comparator (1) 2: Standard of care (1) 2: Usual practice + SYMBICORT RAPIHALER (1) 2: continuation of RAS blocker therapy (1) 2D Telemedicine (1) 3D Telemedicine (1) 40ml blood sample (1) 50 mg/mL Virazole (1) ACE inhibitor, angiotensin receptor blocker (1) ACEIs (1) ASC09/ritonavir group (1) ASC09F+Oseltamivir (1) ATV (1) AZ (1) Abidol Hydrochloride combined with Interferon atomization (1) Acalabrutinib (1) Acetylsalicylic acid (1) Additional biological samples (1) Aerosol-reducing Mask (1) Albuterol - Control (1) Albuterol - Experimental (1) Alferon LDO (1) Allogeneic NK transfer (1) Allogeneic and expanded adipose tissue-derived mesenchymal stromal cells (1) Almitrine (1) Alteplase 100 MG [Activase] (1) Alteplase 50 MG [Activase] (1) Aluminum hydroxide (1) Aluminum hydroxide adjuvant (Alhydrogel®) (1) Amiodarone (1) Amoxicillin-clavulanate (1) Anakinra alone (stages 2b/3) (1) Anakinra and Ruxolitinib (overcome stage 3) (1) Angiotensin 1-7 (1) Angiotensin receptor blocker (1) Angiotensin-Converting Enzyme Inhibitors (ACE-I) and Angiotensin II Receptor Blockers (ARB) (1) Anti- SARS-CoV-2 Plasma (1) Anti-Sars-CoV-2 Convalescent Plasma (1) Anti-coronavirus antibodies (immunoglobulins)obtained with DFPP from convalescent patients (1) Antibody-Rich Plasma from COVID-19 recovered patients (1) Any drug used to treat Covid-19 (1) Apo-Hydroxychloroquine (1) Arbidol Hydrochloride Granules (1) Ascorbic Acid and Folic Acid (1) Ascorbic Acid and Zinc Gluconate (1) Aspirin (1) Aspirin 100mg (1) Aspirin 75mg (1) Aspirin 81 mg (1) Assessment of Dietary Changes in Adults in the Quarantine (1) Assessment of cardiovascular diseases and cardiovascular risk factors (1) Assessment of postnatal depression using the the Edinburgh questionnaire between 4 and 6 weeks after delivery (1) Association of diltiazem and niclosamide (1) Atorvastatin 40mg (1) Attention Bias Modification (ABM) (1) Auricular neuromodulation (1) Auto-questionnaires (patients co infected HIV Sras-CoV-2) (1) Autologous Adipose MSC's (1) Automated oxygen administration - FreeO2 (1) Aviptadil (VIP) (1) Aviptadil by intravenous infusion + maximal intensive care (1) Awake Proning (1) Ayurveda (1) Azinc (1) Azithromycin (Azithro) (1) Azithromycin 500 mg (1) Azithromycin 500 milligram (mg) oral Tablet (1) Azithromycin 500Mg Oral Tablet (1) Azithromycin with amoxicillin/clavulanate (1) BAT (1) BAT + Calcifediol (1) BCG (1) BIOMARKERS IN THE LONG TERM IMPACT OF CORONAVIRUS INFECTION IN THE CARDIORRESPIRATORY SYSTEM (1) BIOVITALS (1) BLD-2660 (1) BM-MSCs (1) BMS-986253 (1) BNT162a1 (1) BNT162b1 (1) BNT162b2 (1) BNT162c2 (1) BR (1) BVRS-GamVac (1) BVRS-GamVac-Combi (1) Bactek-R (1) Bacterial species isolated (1) Baricitinib (janus kinase inhibitor) (1) Baricitinib 4 MG Oral Tablet (1) Baricitinib Oral Tablet (1) Berzosertib (1) Best Available Therapy (1) Best Practice (1) Best Supportive Care (1) Best standard of care (1) Bevacizumab (1) BioMedomics COVID-19 IgM-IgG Rapid Test (1) Biological collection (patients co infected HIV Sras-CoV-2) (1) Biological samples specific to research (1) Biological test (1) Biological: COVID-19 convalescent plasma (1) Biomarkers expression (1) Biosensor (1) Biosensors (1) Blood Test (1) Blood Transfusion (1) Blood and derivatives. (1) Blood donation from convalescent donor (1) Blood plasma (1) Blood samples (collection of 5 mL of blood in a dry tube) (1) Blood sampling (1) Breath test (1) Brief Psychiatric Rating Scale (1) Bromhexine Hydrochloride Tablets (1) Bromhexine Oral Tablet and/or hydroxychloroquine tablet (1) Budesonide Nasal (1) Burnout (1) CAG length <24 (1) CAG length >=24 (1) CAStem (1) CD24Fc (1) CELLECTRA® 2000 (1) CHLORPROMAZINE (CPZ) (1) COPAN swabbing and blood sample collection (1) COVID 19 diagnostic test by PCR (1) COVID-19 IgM/IgG Rapid Testing, mobile device image capture and telemedicine support (1) COVID-19 Pandemic (1) COVID-19 barrier box (1) COVID-19 convalescent plasma (1) COVID-19 diagnostic test (1) COVID-19 exposure (1) COVID-19 infection (1) COVID-19 test, polymerase chain reaction for SARS-CoV-2 (1) COVID-surgRES questionaire (1) COVSurf Drug Delivery System (1) COViage (1) CPAP (1) CT score (1) CT-V (1) CT-imaging (1) CYNK-001 (1) Calcium Channel Blockers (1) Cambridge Validated Viral Detection Method (1) Canakinumab (1) Canakinumab 150 MG/ML [Ilaris] (1) Canakinumab Injection 300mg (1) Canakinumab Injection 600mg (1) Candesartan (1) Caption AI (1) Carboplatin (1) Carrimycin (1) Ceftaroline (1) Ceftriaxone (1) Cell therapy protocol 1 (1) Cell therapy protocol 2 (1) Cellectra 2000 Electroporation (1) Centricyte 1000 (1) ChAdOx1 nCoV-19 (1) ChAdOx1 nCoV-19 boost (1) Chemotherapy (1) Chest computed tomography (CT) (1) Chlorhexidine Gluconate (1) Chloroquine Diphosphate (1) Chloroquine analog (GNS651) (1) Chloroquine diphosphate (1) Chlorpromazine Injection (1) Ciclesonide Metered Dose Inhaler [Alvesco] (1) Clazakizumab (1) Clazakizumab 12.5 mg (1) Clazakizumab 25 mg (1) Clevudine (1) Clinical diagnosis of COVID-19 by a health care professional (1) Clinical examination (1) Clopidogrel (1) Clopidogrel 75mg (1) Cobicistat (1) Colchicine Tablets (1) ColdZyme® mouth spray (1) Collection of samples (1) Combination of Lopinavir /Ritonavir and Interferon beta-1b (1) Combined use of a respiratory broad panel multiplex PCR and procalcitonin (1) Complement dosage (1) Comprehensive treatment (1) Connor-Davidson Resilience Scale 10 items (CD-RISC 10) (1) Continuation of ACEi/ARB (1) Continuation of ARB/ACEI (1) Continuous renal replacement therapy (1) Control arm (1) Control swab (1) Convalescent COVID 19 Plasma (1) Convalescent Plasma (anti-SARS-CoV-2 plasma) (1) Convalescent Plasma Transfusion (1) Convalescent Serum (1) Convalescent anti-SARS-CoV-2 plasma (1) Conventional medicines (Oxygen therapy, alfa interferon via aerosol inhalation, and lopinavir/ritonavir) (1) Conventional medicines (Oxygen therapy, alfa interferon via aerosol inhalation, and lopinavir/ritonavir) and Traditional Chinese Medicines (TCMs) granules (1) Conventional treatment (1) Coping strategies video (1) Cordio App (1) CoronaCideTM COVID-19 IgM/IgG Rapid Test and Premier Biotech COVID-19 IgM/IgG Rapid Test (1) Covid-19 Antibody testing (IgG and IgM) (1) Cross-sectional observational study (1) Cytokine Adsorption (1) Cytokine profile (1) Cytokines dosage (1) DAS181 COVID-19 (1) DAS181 OL (1) DRV (1) Danoprevir+Ritonavir (1) Dapagliflozin 10 MG (1) Darunavir and Cobicistat (1) Data collection and rhinopharyngeal swab (1) Data record (1) Defibrotide 25 mg/kg 24 hours continuous infusion for 15 days (1) Defibrotide Injection (1) Delayed diagnostics Anyplex TMII RV16 Detection (1) Dental pulp mesenchymal stem cells (1) Depression, Anxiety and Stress Scale (1) Determination of physical activity, quality of life, stress levels of isolated people at home with the danger of coronavirus. (1) Dexamethasone (1) Dexamethasone and Hydroxychloroquine (1) Dexmedetomidine Injectable Product (1) Diagnostic test (1) Digital intervention (1) Discontinuation of ACEi/ARB (1) Discontinuation of ARB/ACEI (1) Docetaxel (1) Doppler Echo (1) Drug Isotretinoin (13 cis retinoic acid ) capsules+standard treatment (1) Duodenal biopsy (1) ECCO2R (1) ECG (1) EUROIMMUN assay (1) Eicosapentaenoic acid gastro-resistant capsules (1) Electric pad for human external pain therapy (1) Electrocardiogram, telemetry, echocardiogram, laboratory values (1) Elisa-test for IgM and IgG to SARS-CoV-2 (1) Emapalumab (1) Emtricitabine/tenofovir disoproxil (1) End tidal breath sample (1) Enoxaparin (1) Enoxaparin Prefilled Syringe [Lovenox] (1) Enoxaparin Prophylactic Dose (1) Enoxaparin/Lovenox Intermediate Dose (1) Environmental Decontamination (1) Equipment with smartwatch throughout hospital stay on the general ward (1) Ergoferon (1) Escin (1) Etoposide (1) Evaluation of the epidemiological characteristics of coronavirus infection (SARS-CoV-2) (1) Examine the impact of COVID-19 during pregnancy (1) Exercise brochure (1) Experimental drug (1) Experimental: Questionnaire without precaution information (1) Exposed to the novel coronavirus disease 2019 (1) Exposure (not intervention) - SARS-CoV-2 infection (1) Exposure to the SARS-CoV-2 and its consequences (1) Extra blood sample (1) Extracorporeal Membrane Oxygenation (1) FT516 (1) Favipiravir + Standard of Care (1) Favipiravir tablets (1) Fibrin generation markers assays (1) Fingolimod 0.5 mg (1) Five-days oseltamivir (1) Fixed-duration Hydrocortisone (1) Fixed-duration higher dose Hydrocortisone (1) Fluvoxamine (1) Follow-up at 14 days (1) Fondaparinux (1) GAD-7 (7-item Generalized Anxiety Disorder) (1) GO2 PEEP MOUTHPIECE (1) Galidesivir (1) Ganovo+ritonavir+/-Interferon nebulization (1) Gargle/Mouthwash (1) General health education (1) Gimsilumab (1) Global Longitudinal Strain (1) Glucose tablets (1) Group A HCQ (1) Group B Control (1) Guided online support program (1) HB-adMSC (1) HC (1) HCQ (1) HCQ & AZ (1) HCQ + Intravenous Famotidine (1) HCQ + Placebo (1) HCQ+AZT (1) HFNO (1) HOME-CoV rule implementation (1) Halo Oral Spray (1) Halo Placebo (1) Health Care Worker Survey (1) Helmet non-invasive ventilation (NIV) (1) Heparin Infusion (1) Heparin SC (1) Hidroxicloroquina (1) Hidroxicloroquina + Azitromicina o Lopinavir/ritonavir + Interferon β-1b + Hidroxicloroquina (1) Hidroxicloroquine (1) High does chloroquine or hydroxychloroquine (1) High-Titer COVID-19 Convalescent Plasma (HT-CCP) (1) Honey (1) Hospital anxiety and depression scale (1) Huaier Granule (1) Human Biological samples (1) Human biological samples (1) Human immunoglobulin (1) Human umbilical cord derived CD362 enriched MSCs (1) Humanistic Care (1) Hydoxychloroquine or Chloroquine (1) Hydroxychloroquine + Azithromycin (1) Hydroxychloroquine + Placebo (1) Hydroxychloroquine + azithromycin + / - tocilizumab (1) Hydroxychloroquine + lopinavir/ritonavir (1) Hydroxychloroquine + placebo (1) Hydroxychloroquine - Daily Dosing (1) Hydroxychloroquine - Daily dosing (1) Hydroxychloroquine 200 Mg Oral Tablet (1) Hydroxychloroquine Oral Product (1) Hydroxychloroquine Pre-Exposure Prophylaxis (1) Hydroxychloroquine SAR321068 (1) Hydroxychloroquine Sulfate (HCQ) (1) Hydroxychloroquine Sulfate + Azithromycin (1) Hydroxychloroquine Sulfate + Azythromycin (1) Hydroxychloroquine Sulfate 200 MG (1) Hydroxychloroquine Sulfate 200 MG [Plaquenil] (1) Hydroxychloroquine Sulfate 200 milligram (mg) Tab (1) Hydroxychloroquine Sulfate 400 mg twice a day (1) Hydroxychloroquine Sulfate 600 mg once a day (1) Hydroxychloroquine Sulfate 600 mg twice a day (1) Hydroxychloroquine Sulfate and Azithromycin (1) Hydroxychloroquine Sulfate and Folic Acid (1) Hydroxychloroquine and Azithromycin (1) Hydroxychloroquine and azithromycin treatment (1) Hydroxychloroquine and azithromycin treatment arm. (1) Hydroxychloroquine as post exposure prophylaxis (1) Hydroxychloroquine in combination of Azithromycin (1) Hydroxychloroquine plus Nitazoxanide (1) Hydroxychloroquine plus standard preventive measures (1) Hydroxychloroquine, Azithromycin (1) Hydroxychloroquine, Clindamycin (1) Hydroxychloroquine, Clindamycin, Primaquine - high dose. (1) Hydroxychloroquine, Clindamycin, Primaquine - low dose. (1) Hydroxychloroquine, Doxycycline (1) Hyperbaric oxygen (1) Hyperbaric oxygen therapy (1) Hyperbaric oxygen treatment (HBOT) i.e. inhalation of pressurized oxygen delivered by a hyperbaric chamber (drug/device) (1) Hyperimmune plasma (1) IC14, a monoclonal antibody against CD14 (1) ICU treatment (1) INO-4800 (1) IV Deployment Of cSVF In Sterile Normal Saline IV Solution (1) Ibuprofen (1) IgM and IgG diagnostic kits to SARS-CoV-2 (1) Imatinib (1) Imatinib tablets (1) Immunoglobulin of cured patients (1) Immunological profiling (1) Impact Event Score (1) Impact of Event Scale-Revised (1) Individualised Ayurveda (1) Indomethacin (1) Information-only intervention (1) Inhaled Supplemental Oxygen (1) Inhaled beclomethasone (1) Inhaled budesonide (1) Inhaled nitric oxide gas (1) Injection and infusion of LV-SMENP-DC vaccine and antigen-specific CTLs (1) Injective placebo (1) Insulin regimen (1) Interferon-Alpha2B (1) Interferon-Beta (1) Interferon-β 1a (1) Interferon-β1a (1) Intermediate dose thromboprophylaxis (1) Intermittent prone positioning instructions (1) Internet-delivered cognitive behavior therapy (ICBT) for dysfunctional worry related to the Covid-19 pandemic (1) Interview (1) Intraosseous access (1) Intravenous Immunoglobulin (1) Intravenous access (1) Intravenous drug (1) Intravenous saline injection (Placebo) (1) Isoprinosine (1) Isotonic saline 0.9% (1) Isotretinoin Only Product in Oral Dose Form (1) Isotretinoin(Aerosolized 13 cis retinoic acid) +standard treatment (1) Ivermectin plus Nitazoxanide (1) Ivermectine (1) JNJ-53718678 (1) Kerecis Oral and Nasal Spray (1) Ketamine (1) Ketogenic diet (1) Kevzara sc (1) Laboratory Biomarker Analysis (1) Lactated ringer's solution or sterile saline (1) Leflunomide (1) Lenzilumab (1) Levamisole (1) Levamisole and Isoprinosine (1) Liberase Enzyme (Roche) (1) Linagliptin (1) Linagliptin 5 MG (1) Liquid Peanut Extract (1) Liver injury (1) Loop mediated isothermal amplification COVID-19 (1) Lopinavir / Ritonavir Pill (1) Lopinavir / Ritonavir plus Ribavirin (1) Lopinavir / ritonavir tablets combined with Xiyanping injection (1) Lopinavir / ritonavir, alpha-interferon nebulization (1) Lopinavir 200Mg/Ritonavir 50Mg Tab (1) Lopinavir and Ritonavir Tablets (1) Lopinavir and ritonavir (1) Lopinavir/Ritonavir (1) Lopinavir/ritonavir treatment (1) Low Dose Radiation Therapy (1) Low dose CT (1) Low-dose chloroquine/hydroxychloroquine (1) MRx-4DP0004 (1) MSCs-derived exosomes (1) MVA-MERS-S_DF1 - High Dose (1) MVA-MERS-S_DF1 - Low Dose (1) Machine learning model (1) Macrolide administered for 3-5 days (1) Macrolide administered for up to 14 days (1) Matched Placebo (1) Matched Placebo Hydroxychloroquine (1) Matrix-M Adjuvant (1) Measles-Mumps-Rubella Vaccine (1) Medical Mask (1) Medical/surgical mask (1) Mefloquine (1) Mefloquine + azithromycin + / - tocilizumab (1) Melatonin 2mg (1) MenACWY (1) Meplazumab for Injection (1) Mesenchymal cells (1) Messaging (1) Methylprednisolone Sodium Succinate (1) Microcannula Harvest Adipose Derived tissue stromal vascular fraction (tSVF) (1) Mid dose chloroquine or hydroxychloroquine (1) Mindfulness session(s) (1) Mindfulness-based "STOP touching your face" practice (1) Minocycline (1) Monitoring Visit - Baseline (1) Monitoring Visit - Week 4 (1) Monitoring Visit - Week 8 (1) Montelukast Oral Granules (1) Moxifloxacin or Levofloxacin (1) MultiStem (1) Multifrequency Bioimpedance Spectroscopy (1) Multiple Doses of Anti-SARS-CoV-2 convalescent plasma (1) Mupirocin (1) MuscleSound Ultrasound (1) N-acetylcysteine+ Fuzheng Huayu Tablet (1) N-acetylcysteine+Placebo (1) N95 Respirator (1) N95 respirator (1) NA (no intervention) (1) NIO® (Intraosseous access) (1) NK Cells (1) NK cells,IL15-NK cells,NKG2D CAR-NK cells,ACE2 CAR-NK cells,NKG2D-ACE2 CAR-NK cells (1) NO intervention planned due to the observational study design only a diagnostic testing (1) NSS Saline Placebo (1) NaCl 0.9% (1) Nafamostat Mesilate (1) Naltrexone (1) Naso pharyngeal swab (1) Natural Honey (1) NestCell® (1) New QIAstat-Dx fully automatic multiple PCR detection platform (1) New screening strategy (1) Next generation Sequencing (NGS) analysis (1) Niclosamide (1) Nigella Sativa / Black Cumin (1) Nintedanib 150 MG (1) Nitazoxanide 500 MG (1) Nitazoxanide Tablets (1) Nitric Oxide 0.5 % / Nitrogen 99.5 % Gas for Inhalation (1) Nivolumab Injection (1) No intervention (survey study for medical doctors). (1) No intervention, observational study (1) No special intervention (1) Non Extracorporeal Membrane Oxygenation (1) Non-Interventional (1) Non-convalescent Plasma (control plasma) (1) Normal (9%) Saline (1) Normal Saline Infusion + Maximal intensive care (1) Normal saline (1) Normobaric oxygen therapy (1) Nutrition support (1) Observation of behavior and COVID-19 infection will be conducted. (1) Observation of patients with known, suspected, or at risk for COVID-19 infection (1) Observational (registry) (1) Observational Study (1) Observational only (1) Odd/Even birth year intervention groups (1) Omeprazole 20mg (1) Online Questionnaire (1) Online Survey (1) Oral (1) Oral placebo (1) Other drugs (1) Others(No intervention) (1) Outpatient MRI (1) Oxygen (1) Oxygen Therapy (1) Oxygen-ozone therapy, probiotic supplementation and Standard of care (1) Ozone auto-hemotherapy (1) PD-1 blocking antibody+standard treatment (1) PEEP trial (1) PHQ-9 (9-item Patient Health Questionnaire) (1) PROTECTIVE VENTILATION (1) PSG (1) PSS (Perceived Stress Scale) (1) PTSD (1) Pacebo: Calcium citrate (1) Pathogen-specific aAPC (1) Patient management suffering of coronavirus infection (1) Patient sampling (1) Patients with the treatment agains COVID19 (1) Peginterferon Lambda-1A (1) Peginterferon Lambda-1a (1) Peginterferon lambda alfa-1a subcutaneous injection (1) Pegylated interferon lambda (1) Pembrolizumab (MK-3475) (1) Peripheral blood draw (1) Personalized health education (1) Phosphate buffered saline Placebo (1) Physical Exam (1) Physical Therapy (1) Physiological serum (1) Piclidenoson (1) Piperacillin-tazobactam (1) Placebo (Plasma-Lyte 148) (1) Placebo + Placebo (1) Placebo 250 cc 24 hours continuous infusion for 15 days (1) Placebo Glycerin SLIT (1) Placebo Vaccine (1) Placebo for Azithromycin (1) Placebo for Hydroxychloroquine (1) Placebo of Hydroxychloroquine (1) Placebo of LPV/r Tablets (1) Placebo oral capsule (1) Placebo plus standard preventive measures (1) Placebo solution (1) Placebo: Emtricitabine/tenofovir disoproxil Placebo (1) Placebo: Hydroxychloroquine (1) Plaquenil 200Mg Tablet (1) Plasma Adsorption Cartridge (1) Plasma Donation (1) Point-of-Care Ultrasonography (POCUS) (1) Polysomnography (1) Postpartum women under investigation for Coronavirus or diagnosed with COVID-19 (1) Postural Positioning (1) Povidone-Iodine (1) Povidone-Iodine 0.5% (1) Povidone-Iodine 2% (1) Powered Air purifying respirator (1) Practice details (1) Prazosin (1) Pregnant women under investigation for Coronavirus or diagnosed with COVID-19 (1) Presatovir placebo (1) Probiotic (1) Prone (1) Prone Positioning (1) Prone position (1) Prone positioning (PP) (1) Prospective oberservational registry (1) Prototype swab (1) Psychological and physical rehabilitation based humanistic care (1) Public Health England Gold Standard (1) Pulmonary Physiotherapy Techniques (1) Pulmonary ultrasound (1) Pyridostigmine Bromide (1) Q-NRG Metobolic Cart Device (1) Qualitative interviews (in 40 patients : 20 with COVID-19 and 20 without COVID-19) (1) Quality of Life (1) Questionnaire by phone call (1) Questionnaire with precaution information (1) Questionnaires, spirometry (1) Quick Defense (1) RBA-2 (1) REGN3048 (1) REGN3051 (1) Radiological Detection (1) Ramipril 2.5 MG Oral Capsule (1) Random Donor Plasma (1) Rapid diagnostics using Anyplex TMII RV16 Detection (1) Rapid molecular test (1) Ravulizumab (1) Recombinant Human Interferon α2b Spray (1) Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) (1) Recombinant S protein SARS vaccine (1) Recombinant human angiotensin-converting enzyme 2 (rhACE2) (1) Recombinant human interferon α1β (1) Recombinant novel coronavirus vaccine (Adenovirus type 5 vector) (1) Recombinase aided amplification (RAA) assay (1) Registery Data Collection (1) Remestemcel-L (1) Remestemcel-L® (1) Remote consultation (1) Retrospective data collection (1) Reverse-transcription polymerase chain reaction (RT-PCR) (1) Ribavirin (1) Rifampin (1) Risk of MERS infection (1) Ritonavir+Oseltamivir (1) Rivaroxaban (1) Rivaroxaban 2.5 MG (1) RoActemra iv (1) RoActemra sc (1) Routine care for COVID-19 patients (1) Ruxolitinib administration (1) Ruxolitinib plus simvastatin (1) SAB-301 (1) SAMBA II (Diagnostic for the Real World) (1) SARILUMAB (1) SARS-CoV (1) SARS-CoV-2 IgG Antibody Testing Kit (1) SARS-CoV-2 non-immune Plasma (1) SARS-CoV-2 rS (1) SARS-CoV-2 viral composition (1) SARS-Cov-2 infection (1) SARS-Cov2 testing (1) SLEDD with a L-MOD (1) SPEQ (Specific Psychotic Experiences Questionnaire) - Paranoia and Grandiosity Subscales (1) SPIN-CHAT Program (1) STC-19 score (1) Saline (1) Saline Nasal Irrigation (1) Saline containing 1% Human serum albumin（solution of MSC） (1) Saline with Baby Shampoo Nasal Irrigation (1) Saliva (1) Sampling salivary (1) Sargramostim (1) Sarilumab SAR153191 (1) Satisfaction evaluation (1) Scanning Chest X-rays and performing AI algorithms on images (1) Schirmer Test I (1) Self-prone position recommendation (1) SensiumVitals wearable sensor (1) Sequencing (1) Serological test (1) Serology (1) Serum SARs COV 2 IGg screening in health care workers (1) Serum test (1) Serum testing (1) Sevoflurane (1) Shock-dependent hydrocortisone (1) Simvastatin (1) Sirolimus 1 MG/ML (1) Social media & news consumption (1) Sodium Chloride 9mg/mL (1) Software Messaging (1) Sputum and blood sampling (1) Sputum sample (1) Stamaril (live attenuated yellow fever vaccine) (1) Standar of care (1) Standard 12-lead ECG, NT-proBNP, echocardiography (1) Standard Donor Plasma (1) Standard Mask (1) Standard Plasma (1) Standard Plasma (FFP) (1) Standard Public Health measures (1) Standard administration of oxygen flow (1) Standard medical care (1) Standard of Care (Intravenous access) (1) Standard of Care (SOC) (1) Standard of Care thromboprophylaxis (1) Standard of care (SOC) (1) Standard of care therapy (1) Standard of care treatment (1) Standard of care. (1) Standard screening strategy (1) Standard supportive care (1) Standard therapy for COVID-19 according to the stablished hospital protocols. (1) Standard therapy of COVID-19 (1) Standard therapy recommended by the Ministry of Health of the Russian Federation and Dalargin inhalation (1) Standard therapy recommended by the Ministry of Health of the Russian Federation and Dalargin intramuscular injection (1) Standard therapy recommended by the Ministry of Health of the Russian Federation and Dalargin intramuscular injection combined with Dalargin inhalation (1) Standard therapy recommended by the Ministry of Health of the Russian Federation. (1) Standards of Care (1) Stannous protoporphyrin (90mg) (1) Stem Cell Educator-Treated Mononuclear Cells Apheresis (1) Sterile Normal Saline for Intravenous Use (1) Sterile Water for Injection (1) Streptokinase (1) Study A (1) Study B (1) Study C (1) Study Group (1) Supportive Care (1) Surgery (1) Surgical facial mask (1) Survey (1) Survey and Questionnaire (1) Suspension or Maintenance of Angiotensin Receptor Blockers and Angiotensin-converting Enzyme Inhibitors (1) Swallowing evaluation with the EAT-10 and the volume-viscosity swallowing test (V-VST) (1) Symptoms questionnare (1) Systemic indirect endovenous ozone therapy (1) T-cell receptor (TCR) repertoire (1) T89 (1) TAK-981 (1) TAVR or SAVR (1) TCM prescriptions (1) TD-0903 (1) TEM-tPA (1) TJ003234 (1) Tacrolimus (1) Taste and olfactory function evaluation (1) Tele-interventions related to diabetes management and mental well-being (1) Tele-medicine platform (1) Teleconsultation either by phone or by computer consultation (1) Telephone follow-up (1) Telephone survey (1) Telerehabilitation-Based (1) Telmisartan 40mg (1) Telmisartan arm will receive 80 mg Telmisartan twice daily plus standard care. (1) Ten-days oseltamivir (1) Tested for SARS-CoV-2 (regardless of the result) (1) Testing Sensitivity for SARS-CoV-2 Virus in Symptomatic Individuals (1) Tests (1) Tetrandrine (1) Thalidomide (1) The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care: (1) The Vie Scope laryngoscope (1) The standard Macintosh laryngoscope (1) Therapeutic Anticoagulation (1) There is no intervention in this study (1) Thiazide or Thiazide-like diuretics (1) Thoracic CT Scan (1) Throat swab and/or nasopharyngeal swab (1) Thrombin Generation Assay (TGA) (1) Thrombin generation test assay (1) Thrombomodulin Modified Thrombin Generation Assay (TGA-TM) (1) Thromboprophylaxis (1) Thymosin+standard treatment (1) Tinzaparin or unfractionated heparin (1) Tirofiban Injection (1) To assess for development of IgG antibodies against SARS-CoV2 (1) Tociliuzumab (1) Tocilizumab 20 MG/ML Intravenous Solution [ACTEMRA] (1) Tocilizumab Injection (1) Toraymyxin PMX-20R (PMX Cartridge) (1) Tradipitant (1) Traditional Chinese Medicine Prescription (1) Transfusion of COVID-19 convalescent plasma (1) Transpulmonary thermodilution (1) Treatment and prophylaxis (1) Treatment with Dexmedetomidine (1) Trimethoprim Sulfamethoxazole (TMP/SMX) (1) Two doses of high dosage inactivated SARS-CoV-2 vaccine at the emergency vaccination schedule (1) Two doses of high dosage inactivated SARS-CoV-2 vaccine at the routine vaccination schedule (1) Two doses of medium dosage inactivated SARS-CoV-2 vaccine at the emergency vaccination schedule (1) Two doses of medium dosage inactivated SARS-CoV-2 vaccine at the routine vaccination schedule (1) Two doses of placebo at the emergency vaccination schedule (1) Two doses of placebo at the routine vaccination schedule (1) ULTRAPROTECTIVE VENTILATION (1) UNIKINON (Chloroquine phosphate) 200mg tablets (1) Ultrasound lung imaging as part of FAST+ evaluation (1) Umbilical Cord Mesenchymal Stem Cells (1) Umbilical cord Wharton's jelly-derived human (1) Umifenovir (1) Unfractionated heparin (1) Urine Test (1) Urine sample (1) Use of social media during COVID-19 (1) Usual antibiotic treatment (1) Usual care (1) Usual care positioning with no instructions (1) VC (1) VRC-SRSDNA015-00-VP (1) Vaccine (1) Valsartan (Diovan) (1) Vazegepant (BHV-3500) (1) Venepuncture (1) Ventil - a gas flow divider (1) Verapamil (1) Video based aerobic exercise (1) Video based exercise (1) Video-Based (1) Views and experiences of health care professionals working in intensive care units during the COVID-19 pandemic (1) VitalConnect Vital Sign Patch (1) Vitamins (1) VivaDiag™ COVID-19 lgM/IgG Rapid Test (1) WHO recommendations (waiting condition) (1) WJ-MSCs (1) Web application users (1) Web-based psychosocial peer-to-peer support (1) Weekly Assessment (1) Whole Genome Analysis (1) XPro1595 (1) Xiyanping injection (1) Yin Hu Qing Wen Granula(low does) (1) Yinhu Qingwen Granula (1) Zaritt Burden Interview (1) Zinc (1) Zinc Gluconate (1) Zinc Sulfate (1) Zithromax Oral Product (1) a specifically designed self-administered questionnaire (1) additional blood tubes (1) all treatment about COVID-2019 (1) allogeneic human dental pulp stem cells (BSH BTC & Utooth BTC) (1) alveolar recruitment (1) amoxicillin/clavulanate (1) artus Influenza A/B RT-PCR Test (1) azithromycin (1) bacTRL-Spike (1) bidirectional oxygenation mouthpiece (1) biological samples collection (1) blood donation SMS (1) blood draw (1) blood samples (1) captopril 25mg (1) care modalities (1) chlorine dioxide 3000 ppm (1) chloroquine (1) cholecalciferol 200,000 IU (1) cholecalciferol 50,000 IU (1) collection of biological samples (1) conjunctival swab (1) consultation (1) convalescent plasma from recovered COVID 19 donor (1) conventional management of patients (1) conventional oxygen (1) daily syndromic surveillance (1) eculizumab (1) exercise brochure (1) favipiravir (1) favipiravir tablets+chloroquine phosphatetablets tablets (1) global survey (1) high flow nasal cannula (HFNC) (1) high-titer anti-Sars-CoV-2 plasma (1) hormones (1) hospitalized children with Covid19 (1) hydroxychloroquine + azithromycin (1) hydroxychloroquine in combination with camostat mesylate (1) hydroxychloroquine placebo (1) hydroxychloroquine sulfate 200 MG (1) hyperbaric oxygen therapy (HBOT) (1) hyperimmune plasma (1) iNO (inhaled nitric oxide) delivered via the INOpulse Delivery System (1) identify SARS-CoV-2 infection by serology (1) intradermal injection of BCG Vaccine (1) isocaloric/isonutrigenous ONS (1) laboratory biomarkers (1) lopinavir/ritonavir (1) lopinavir/ritonavir group (1) lopinavir/ritonavir tablets or Arbidol or chloroquine phosphate (1) lung ultrasound (1) mRNA-1273 (1) mechanical ventilation (1) meplazumab for injection (1) mesenchymal stem cells (1) methylprednisolone therapy (1) modification of the planned therapeutic management (1) monthly serologic IgM/G test (1) mouthrinse with bêta-cyclodextrin and citrox (1) mouthrinse without bêta-cyclodextrin and citrox (1) muscle ultrasound (1) nasopharyngeal Covid 19 RT-PCR (1) nasopharyngeal swab (1) newborns from covid 19 positive mothers (1) no intervention (1) no interventional study (1) non (1) non-RAS blocking antihypertensives (1) nosocomial infection/hospital acquired infection (1) observation (1) olfactory and gustatory tests (1) oral nutrition supplement (ONS) enriched in eicosapentaenoic acid, gamma-linolenic acid and antioxidants (1) oxygen treatment (1) oxyhydrogen (1) pathogen reduced SARS-CoV-2 convalescent plasma (1) pirfenidone (1) placebo for clazakizumab (1) plasma therapy using convalescent plasma with antibody against SARS-CoV-2 (1) prayer (1) prednisolone (1) prone position (1) quesionnair (1) questionnair about Emerging Legal and Ehical Disputes Over Patient Confidentiality (1) quetionnary (1) rapid salivary test (1) recombinant human interferon Alpha-1b (1) remdesivir (1) samling of oropharynx and nasopharynx (1) serological test (1) serum chemistry analysis (1) serum inflammatory biomarkers (1) severe covid-19 pneumonia with ET (1) standard medical treatment (1) standard of care (1) standard operating procedures (1) standard procedure (1) standard therapy (1) standard treatment (1) standardized Lung Ultrasound (LUS) examination (1) systemic treatment (1) telehealth applications (1) thalidomide (1) this study is non- interventional (1) thromboprophylaxis with low-molecular-weight heparin or fondaparinux (1) thymosin alpha 1 (1) trimethoprim/sulfamethoxazole (1) turkish physicians (1) vaccine BCG (1) vaccine candidate MVA-MERS-S (1) vv-ECMO + cytokine adsorption (Cytosorb adsorber) (1) vv-ECMO only (no cytokine adsorption) (1) washed microbiota transplantation (1) γ-Globulin (1)
Covid 19 Research using Clinical Trials (Home Page)
CAStemWiki
Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation
Correlated Drug Terms (2)
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug389 | Hydroxychloroquine and Azithromycin Wiki | 1.00 |
| drug81 | Azinc Wiki | 1.00 |
Correlated MeSH Terms (7)
| Name (Synonyms) | Correlation | |
|---|---|---|
| D055370 | Lung Injury NIH | 0.32 |
| D011024 | Pneumonia, Viral NIH | 0.17 |
| D055371 | Acute Lung Injury NIH | 0.16 |
| D013577 | Syndrome NIH | 0.15 |
| D012127 | Respiratory Distress Syndrome, Newborn NIH | 0.15 |
| D012128 | Respiratory Distress Syndrome, Adult NIH | 0.13 |
| D011014 | Pneumonia NIH | 0.08 |
Correlated HPO Terms (0)
| Name (Synonyms) | Correlation |
|---|
There is one clinical trial.
Clinical Trials
1 Safety and Efficacy Study of Human Embryonic Stem Cells Derived M Cells (CAStem) for the Treatment of Severe COVID-19 Associated With or Without Acute Respiratory Distress Syndrome (ARDS)
A phase1/2, open label, dose escalation, safety and early efficacy study of CAStem for the treatment of severe COVID-19 associated with or without ARDS.
NCT04331613 COVID-19 Acute Respiratory Distress Syndrome Virus; Pneumonia Acute Lung Injury Biological: CAStem MeSH:Pneumonia, Viral Pneumonia Respiratory Distress Syndrome, Newborn Respiratory Distress Syndrome, Adult Acute Lung Injury Lung Injury Syndrome
HPO:Pneumonia
Primary Outcomes
Description: Frequency of adverse reaction (AE) and severe adverse reaction (SAE) within 28 days after treatment
Measure: Adverse reaction (AE) and severe adverse reaction (SAE) Time: Within 28 days after treatment
Description: Evaluation by chest CT
Measure: Changes of lung imaging examinations Time: Within 28 days after treatment
Secondary Outcomes
Description: Marker for SARS-CoV-2
Measure: Time to SARS-CoV-2 RT-PCR negative Time: Within 28 days after treatment
Description: The duration of a fever above 37.3 degrees Celsius
Measure: Duration of fever (Celsius) Time: Within 28 days after treatment
Description: Marker for efficacy
Measure: Changes of blood oxygen (%) Time: Within 28 days after treatment
Description: Marker for efficacy
Measure: Rate of all-cause mortality within 28 days Time: Within 28 days after treatment
Description: Counts of lymphocyte in a litre (L) of blood
Measure: Lymphocyte count (*10^9/L) Time: Within 28 days after treatment
Description: Alanine aminotransferase in unit (U)/litre(L)
Measure: Alanine aminotransferase (U/L) Time: Within 28 days after treatment
Description: Creatinine in micromole (umol)/litre(L)
Measure: Creatinine (umol/L) Time: Within 28 days after treatment
Description: Creatine kinase in U/L
Measure: Creatine kinase (U/L) Time: Within 28 days after treatment
Description: C-reactive in microgram (mg)/litre(L)
Measure: C-reactive protein (mg/L) Time: Within 28 days after treatment
Description: Procalcitonin in nanogram (ng)/litre(L)
Measure: Procalcitonin (ng/L) Time: Within 28 days after treatment
Description: Lactate in millimole(mmol)/litre(L)
Measure: Lactate (mmol/L) Time: Within 28 days after treatment
Description: IL-1beta in picogram(pg)/millilitre(mL)
Measure: IL-1beta (pg/mL) Time: Within 28 days after treatment
Description: IL-2 in pg/mL
Measure: IL-2 (pg/mL) Time: Within 28 days after treatment
Description: IL-6 in pg/mL
Measure: IL-6 (pg/mL) Time: Within 28 days after treatment
Description: IL-8 in pg/mL
Measure: IL-8 (pg/mL) Time: Within 28 days after treatment
Related HPO nodes (Using clinical trials)
HP:0002090: Pneumonia
Genes 208
TIMM8A DNAH9 GAS8 DNAH11 TNFRSF11A TBC1D24 SPAG1 MS4A1 GAS2L2 CCDC151 NIPBL BTK LIG4 NFKB2 TCIRG1 IGLL1 RNF168 STAT3 TAF1 RSPH4A CFTR NME8 DNAAF4 LEP CCDC65 NADK2 CD55 COL11A2 NHLRC1 PEPD CFAP300 LTBP3 WAS DNAI1 TBCD IL2RG GFI1 NBN RSPH1 CCDC39 PMM2 ICOS TNFSF12 IFNGR1 CARD11 SFTPC DNAL1 OFD1 ZMYND10 IL21R FMO3 SLC35A1 PLOD1 ORC6 RAG2 CACNA1C GAS8 RYR1 CFAP298 GNPTAB TNFRSF13B KDM6A PANK2 RANBP2 CYBA USB1 UBB DOCK8 ADA DNAAF2 KMT2D SAMD9 MUC5B IL7R DNAAF1 ICOS RAG2 CARD11 PTPRC ALMS1 NOTCH3 NSMCE3 DNAI1 TNFRSF13C GRHL3 EGFR IL2RG DNAAF6 PNP DNAH5 SETBP1 CR2 CD3E ADA MASP2 SFTPA2 ACTA1 RAC1 TTC25 FCGR2A ZAP70 SPEF2 IGHM DNAAF5 NBN CD247 DDR2 CD19 ACADVL KIAA0586 TK2 BLNK ARMC4 SGCG RAG1 CXCR4 NCF1 SRP54 FOXP3 IRF8 CFAP221 RNU4ATAC KCNJ6 LRBA CD3D P4HTM SELENON CCDC114 TNFRSF13B PLG DCLRE1C SLC25A24 DCLRE1C ICOS IL7R FOXJ1 JAK3 IL2RG CASP8 RAG1 OSTM1 CFAP410 CCNO NCF2 UNC119 TNFRSF13C JAK3 RNF125 STK36 POLA1 CD19 CR2 DNAH1 RSPH3 RSPH9 CYBB DRC1 DCLRE1C CCDC103 DNAAF3 LRRC56 PIGN LRRC6 SP110 PRKCD ACP5 CCDC40 SLC35C1 BTK MTHFD1 PGM3 RAG1 TERT CHD7 CFB TGFB1 RNU4ATAC SMARCD2 NKX2-1 OFD1 ZBTB24 BTK DNAI2 WDR19 ZAP70 CD79B CD81 COL11A2 NFIX RAG2 ELANE AFF4 NFKB1 IL2RG TNFRSF13C TNFSF12 CCDC114 ADA GBA DNAJB13 RPGR CSPP1 RMRP EPM2A DNMT3B NFKB2 MCIDAS HYDIN SNP 0
Primary Outcomes
Description: Frequency of adverse reaction (AE) and severe adverse reaction (SAE) within 28 days after treatment
Measure: Adverse reaction (AE) and severe adverse reaction (SAE) Time: Within 28 days after treatmentDescription: Evaluation by chest CT
Measure: Changes of lung imaging examinations Time: Within 28 days after treatmentSecondary Outcomes
Description: Marker for SARS-CoV-2
Measure: Time to SARS-CoV-2 RT-PCR negative Time: Within 28 days after treatmentDescription: The duration of a fever above 37.3 degrees Celsius
Measure: Duration of fever (Celsius) Time: Within 28 days after treatmentDescription: Marker for efficacy
Measure: Changes of blood oxygen (%) Time: Within 28 days after treatmentDescription: Marker for efficacy
Measure: Rate of all-cause mortality within 28 days Time: Within 28 days after treatmentDescription: Counts of lymphocyte in a litre (L) of blood
Measure: Lymphocyte count (*10^9/L) Time: Within 28 days after treatmentDescription: Alanine aminotransferase in unit (U)/litre(L)
Measure: Alanine aminotransferase (U/L) Time: Within 28 days after treatmentDescription: Creatinine in micromole (umol)/litre(L)
Measure: Creatinine (umol/L) Time: Within 28 days after treatmentDescription: Creatine kinase in U/L
Measure: Creatine kinase (U/L) Time: Within 28 days after treatmentDescription: C-reactive in microgram (mg)/litre(L)
Measure: C-reactive protein (mg/L) Time: Within 28 days after treatmentDescription: Procalcitonin in nanogram (ng)/litre(L)
Measure: Procalcitonin (ng/L) Time: Within 28 days after treatmentDescription: Lactate in millimole(mmol)/litre(L)
Measure: Lactate (mmol/L) Time: Within 28 days after treatmentDescription: IL-1beta in picogram(pg)/millilitre(mL)
Measure: IL-1beta (pg/mL) Time: Within 28 days after treatmentDescription: IL-2 in pg/mL
Measure: IL-2 (pg/mL) Time: Within 28 days after treatmentDescription: IL-6 in pg/mL
Measure: IL-6 (pg/mL) Time: Within 28 days after treatmentDescription: IL-8 in pg/mL
Measure: IL-8 (pg/mL) Time: Within 28 days after treatment