Covid 19 Clinical Trials

CovidResearchTrials by Shray Alag

drug564: Non-convalescent Plasma (control plasma)

Hydroxychloroquine (64)

Azithromycin (22)

Placebo oral tablet (20)

Tocilizumab (16)

Remdesivir (11)

Hydroxychloroquine Sulfate (10)

Lopinavir/ritonavir (10)

Standard of Care (9)

Convalescent Plasma (8)

Methylprednisolone (8)

No intervention (8)

Standard of care (8)

Chloroquine (6)

Favipiravir (6)

SnPP Protoporphyrin (6)

Oseltamivir (5)

Ruxolitinib (5)

Convalescent plasma (4)

Questionnaire (4)

Standard care (4)

Telerehabilitation (4)

blood sampling (4)

Ascorbic Acid (3)

BCG Vaccine (3)

Blood sample (3)

COVID-19 RT-PCR (3)

Camostat Mesilate (3)

Control group (3)

Hydrocortisone (3)

Hydroxychloroquine (HCQ) (3)

Interferon Beta-1A (3)

Interferon Beta-1B (3)

Lopinavir / Ritonavir (3)

Lung ultrasound (3)

Nitric Oxide Gas (3)

Standard treatment (3)

Suspension of heat killed (autoclaved) Mycobacterium w (3)

Telemedicine (3)

anti-SARS-CoV-2 convalescent plasma (3)

blood sample (3)

hydroxychloroquine (3)

ACE inhibitor (2)

Abidol hydrochloride (2)

Azithromycin Tablets (2)

Baricitinib (2)

Bevacizumab Injection (2)

COVID-19 Serology (2)

ChAdOx1 MERS (2)

Chloroquine Sulfate (2)

Chloroquine or Hydroxychloroquine (2)

Chloroquine phosphate (2)

Data collection (2)

Dexamethasone injection (2)

Dornase Alfa Inhalation Solution [Pulmozyme] (2)

Doxycycline (2)

Echocardiography (2)

Hydroxychloroquine + azithromycin (2)

Hydroxychloroquine - Weekly Dosing (2)

Hydroxychloroquine Sulfate Loading Dose (2)

Hydroxychloroquine Sulfate Regular dose (2)

Hydroxychloroquine sulfate (2)

L-ascorbic acid (2)

Leronlimab (700mg) (2)

Mesenchymal Stromal Cells (2)

NORS (Nitric Oxide Releasing Solution) (2)

Nasopharyngeal swab (2)

Nitazoxanide (2)

Nitric Oxide (2)

No Intervention (2)

Online questionnaire (2)

PUL-042 Inhalation Solution (2)

Povidone-Iodine Nasal Spray and Gargle (2)

Prone positioning (2)

Questionnaires (2)

Remdesivir placebo (2)

Ruxolitinib Oral Tablet (2)

Single Dose of Hydroxychloroquine (2)

SivoMixx (200 billion) (2)

Standard Care (2)

Sulfonated tetra-anthracenyl porphyrin (2)

Telmisartan (2)

Tocilizumab (TCZ) (2)

basic treatment (2)

convalescent plasma (2)

observational (2)

oxygen therapy (2)

pregnant women with laboratory-confirmed 2019-n-CoV (2)

retrospective analysis (2)

self-administered questionnaire (2)

standard care (2)

"Calm" is a mindfulness meditation mobile app (1)

(Standard of Care) SoC (1)

- Synthetic anti-malarial drugs (1)

0.9% sodium chloride (normal saline) (1)

100 mg/mL Virazole (1)

1: Naproxen (1)

1: Prone positioning (1)

1: Usual practice (1)

1: discontinuation of RAS blocker therapy (1)

2019-nCoV PCR (1)

2: No instruction regarding positioning (1)

2: Placebo Comparator (1)

2: Standard of care (1)

2: Usual practice + SYMBICORT RAPIHALER (1)

2: continuation of RAS blocker therapy (1)

2D Telemedicine (1)

3D Telemedicine (1)

40ml blood sample (1)

50 mg/mL Virazole (1)

ACE inhibitor, angiotensin receptor blocker (1)

ASC09/ritonavir group (1)

ASC09F+Oseltamivir (1)

Abidol Hydrochloride combined with Interferon atomization (1)

Acalabrutinib (1)

Acetylsalicylic acid (1)

Additional biological samples (1)

Aerosol-reducing Mask (1)

Albuterol - Control (1)

Albuterol - Experimental (1)

Alferon LDO (1)

Allogeneic NK transfer (1)

Allogeneic and expanded adipose tissue-derived mesenchymal stromal cells (1)

Alteplase 100 MG [Activase] (1)

Alteplase 50 MG [Activase] (1)

Aluminum hydroxide (1)

Aluminum hydroxide adjuvant (Alhydrogel®) (1)

Amoxicillin-clavulanate (1)

Anakinra alone (stages 2b/3) (1)

Anakinra and Ruxolitinib (overcome stage 3) (1)

Angiotensin 1-7 (1)

Angiotensin receptor blocker (1)

Angiotensin-Converting Enzyme Inhibitors (ACE-I) and Angiotensin II Receptor Blockers (ARB) (1)

Anti- SARS-CoV-2 Plasma (1)

Anti-Sars-CoV-2 Convalescent Plasma (1)

Anti-coronavirus antibodies (immunoglobulins)obtained with DFPP from convalescent patients (1)

Antibody-Rich Plasma from COVID-19 recovered patients (1)

Any drug used to treat Covid-19 (1)

Apo-Hydroxychloroquine (1)

Arbidol Hydrochloride Granules (1)

Ascorbic Acid and Folic Acid (1)

Ascorbic Acid and Zinc Gluconate (1)

Aspirin 100mg (1)

Aspirin 75mg (1)

Aspirin 81 mg (1)

Assessment of Dietary Changes in Adults in the Quarantine (1)

Assessment of cardiovascular diseases and cardiovascular risk factors (1)

Assessment of postnatal depression using the the Edinburgh questionnaire between 4 and 6 weeks after delivery (1)

Association of diltiazem and niclosamide (1)

Atorvastatin 40mg (1)

Attention Bias Modification (ABM) (1)

Auricular neuromodulation (1)

Auto-questionnaires (patients co infected HIV Sras-CoV-2) (1)

Autologous Adipose MSC's (1)

Automated oxygen administration - FreeO2 (1)

Aviptadil (VIP) (1)

Aviptadil by intravenous infusion + maximal intensive care (1)

Awake Proning (1)

Azithromycin (Azithro) (1)

Azithromycin 500 mg (1)

Azithromycin 500 milligram (mg) oral Tablet (1)

Azithromycin 500Mg Oral Tablet (1)

Azithromycin with amoxicillin/clavulanate (1)

BAT + Calcifediol (1)

BIOMARKERS IN THE LONG TERM IMPACT OF CORONAVIRUS INFECTION IN THE CARDIORRESPIRATORY SYSTEM (1)

BVRS-GamVac (1)

BVRS-GamVac-Combi (1)

Bacterial species isolated (1)

Baricitinib (janus kinase inhibitor) (1)

Baricitinib 4 MG Oral Tablet (1)

Baricitinib Oral Tablet (1)

Berzosertib (1)

Best Available Therapy (1)

Best Practice (1)

Best Supportive Care (1)

Best standard of care (1)

Bevacizumab (1)

BioMedomics COVID-19 IgM-IgG Rapid Test (1)

Biological collection (patients co infected HIV Sras-CoV-2) (1)

Biological samples specific to research (1)

Biological test (1)

Biological: COVID-19 convalescent plasma (1)

Biomarkers expression (1)

Blood Transfusion (1)

Blood and derivatives. (1)

Blood donation from convalescent donor (1)

Blood plasma (1)

Blood samples (collection of 5 mL of blood in a dry tube) (1)

Blood sampling (1)

Breath test (1)

Brief Psychiatric Rating Scale (1)

Bromhexine Hydrochloride Tablets (1)

Bromhexine Oral Tablet and/or hydroxychloroquine tablet (1)

Budesonide Nasal (1)

CAG length <24 (1)

CAG length >=24 (1)

CELLECTRA® 2000 (1)

CHLORPROMAZINE (CPZ) (1)

COPAN swabbing and blood sample collection (1)

COVID 19 diagnostic test by PCR (1)

COVID-19 IgM/IgG Rapid Testing, mobile device image capture and telemedicine support (1)

COVID-19 Pandemic (1)

COVID-19 barrier box (1)

COVID-19 convalescent plasma (1)

COVID-19 diagnostic test (1)

COVID-19 exposure (1)

COVID-19 infection (1)

COVID-19 test, polymerase chain reaction for SARS-CoV-2 (1)

COVID-surgRES questionaire (1)

COVSurf Drug Delivery System (1)

Calcium Channel Blockers (1)

Cambridge Validated Viral Detection Method (1)

Canakinumab (1)

Canakinumab 150 MG/ML [Ilaris] (1)

Canakinumab Injection 300mg (1)

Canakinumab Injection 600mg (1)

Candesartan (1)

Carboplatin (1)

Ceftaroline (1)

Ceftriaxone (1)

Cell therapy protocol 1 (1)

Cell therapy protocol 2 (1)

Cellectra 2000 Electroporation (1)

Centricyte 1000 (1)

ChAdOx1 nCoV-19 (1)

ChAdOx1 nCoV-19 boost (1)

Chemotherapy (1)

Chest computed tomography (CT) (1)

Chlorhexidine Gluconate (1)

Chloroquine Diphosphate (1)

Chloroquine analog (GNS651) (1)

Chloroquine diphosphate (1)

Chlorpromazine Injection (1)

Ciclesonide Metered Dose Inhaler [Alvesco] (1)

Clazakizumab (1)

Clazakizumab 12.5 mg (1)

Clazakizumab 25 mg (1)

Clinical diagnosis of COVID-19 by a health care professional (1)

Clinical examination (1)

Clopidogrel (1)

Clopidogrel 75mg (1)

Colchicine Tablets (1)

ColdZyme® mouth spray (1)

Collection of samples (1)

Combination of Lopinavir /Ritonavir and Interferon beta-1b (1)

Combined use of a respiratory broad panel multiplex PCR and procalcitonin (1)

Complement dosage (1)

Comprehensive treatment (1)

Connor-Davidson Resilience Scale 10 items (CD-RISC 10) (1)

Continuation of ACEi/ARB (1)

Continuation of ARB/ACEI (1)

Continuous renal replacement therapy (1)

Control arm (1)

Control swab (1)

Convalescent COVID 19 Plasma (1)

Convalescent Plasma (anti-SARS-CoV-2 plasma) (1)

Convalescent Plasma Transfusion (1)

Convalescent Serum (1)

Convalescent anti-SARS-CoV-2 plasma (1)

Conventional medicines (Oxygen therapy, alfa interferon via aerosol inhalation, and lopinavir/ritonavir) (1)

Conventional medicines (Oxygen therapy, alfa interferon via aerosol inhalation, and lopinavir/ritonavir) and Traditional Chinese Medicines (TCMs) granules (1)

Conventional treatment (1)

Coping strategies video (1)

CoronaCideTM COVID-19 IgM/IgG Rapid Test and Premier Biotech COVID-19 IgM/IgG Rapid Test (1)

Covid-19 Antibody testing (IgG and IgM) (1)

Cross-sectional observational study (1)

Cytokine Adsorption (1)

Cytokine profile (1)

Cytokines dosage (1)

DAS181 COVID-19 (1)

Danoprevir+Ritonavir (1)

Dapagliflozin 10 MG (1)

Darunavir and Cobicistat (1)

Data collection and rhinopharyngeal swab (1)

Data record (1)

Defibrotide 25 mg/kg 24 hours continuous infusion for 15 days (1)

Defibrotide Injection (1)

Delayed diagnostics Anyplex TMII RV16 Detection (1)

Dental pulp mesenchymal stem cells (1)

Depression, Anxiety and Stress Scale (1)

Determination of physical activity, quality of life, stress levels of isolated people at home with the danger of coronavirus. (1)

Dexamethasone (1)

Dexamethasone and Hydroxychloroquine (1)

Dexmedetomidine Injectable Product (1)

Diagnostic test (1)

Digital intervention (1)

Discontinuation of ACEi/ARB (1)

Discontinuation of ARB/ACEI (1)

Doppler Echo (1)

Drug Isotretinoin (13 cis retinoic acid ) capsules+standard treatment (1)

Duodenal biopsy (1)

EUROIMMUN assay (1)

Eicosapentaenoic acid gastro-resistant capsules (1)

Electric pad for human external pain therapy (1)

Electrocardiogram, telemetry, echocardiogram, laboratory values (1)

Elisa-test for IgM and IgG to SARS-CoV-2 (1)

Emtricitabine/tenofovir disoproxil (1)

End tidal breath sample (1)

Enoxaparin Prefilled Syringe [Lovenox] (1)

Enoxaparin Prophylactic Dose (1)

Enoxaparin/Lovenox Intermediate Dose (1)

Environmental Decontamination (1)

Equipment with smartwatch throughout hospital stay on the general ward (1)

Evaluation of the epidemiological characteristics of coronavirus infection (SARS-CoV-2) (1)

Examine the impact of COVID-19 during pregnancy (1)

Exercise brochure (1)

Experimental drug (1)

Experimental: Questionnaire without precaution information (1)

Exposed to the novel coronavirus disease 2019 (1)

Exposure (not intervention) - SARS-CoV-2 infection (1)

Exposure to the SARS-CoV-2 and its consequences (1)

Extra blood sample (1)

Extracorporeal Membrane Oxygenation (1)

Favipiravir + Standard of Care (1)

Favipiravir tablets (1)

Fibrin generation markers assays (1)

Fingolimod 0.5 mg (1)

Five-days oseltamivir (1)

Fixed-duration Hydrocortisone (1)

Fixed-duration higher dose Hydrocortisone (1)

Fluvoxamine (1)

Follow-up at 14 days (1)

Fondaparinux (1)

GAD-7 (7-item Generalized Anxiety Disorder) (1)

GO2 PEEP MOUTHPIECE (1)

Galidesivir (1)

Ganovo+ritonavir+/-Interferon nebulization (1)

Gargle/Mouthwash (1)

General health education (1)

Global Longitudinal Strain (1)

Glucose tablets (1)

Group A HCQ (1)

Group B Control (1)

Guided online support program (1)

HCQ + Intravenous Famotidine (1)

HCQ + Placebo (1)

HOME-CoV rule implementation (1)

Halo Oral Spray (1)

Halo Placebo (1)

Health Care Worker Survey (1)

Helmet non-invasive ventilation (NIV) (1)

Heparin Infusion (1)

Hidroxicloroquina (1)

Hidroxicloroquina + Azitromicina o Lopinavir/ritonavir + Interferon β-1b + Hidroxicloroquina (1)

Hidroxicloroquine (1)

High does chloroquine or hydroxychloroquine (1)

High-Titer COVID-19 Convalescent Plasma (HT-CCP) (1)

Hospital anxiety and depression scale (1)

Huaier Granule (1)

Human Biological samples (1)

Human biological samples (1)

Human immunoglobulin (1)

Human umbilical cord derived CD362 enriched MSCs (1)

Humanistic Care (1)

Hydoxychloroquine or Chloroquine (1)

Hydroxychloroquine + Azithromycin (1)

Hydroxychloroquine + Placebo (1)

Hydroxychloroquine + azithromycin + / - tocilizumab (1)

Hydroxychloroquine + lopinavir/ritonavir (1)

Hydroxychloroquine + placebo (1)

Hydroxychloroquine - Daily Dosing (1)

Hydroxychloroquine - Daily dosing (1)

Hydroxychloroquine 200 Mg Oral Tablet (1)

Hydroxychloroquine Oral Product (1)

Hydroxychloroquine Pre-Exposure Prophylaxis (1)

Hydroxychloroquine SAR321068 (1)

Hydroxychloroquine Sulfate (HCQ) (1)

Hydroxychloroquine Sulfate + Azithromycin (1)

Hydroxychloroquine Sulfate + Azythromycin (1)

Hydroxychloroquine Sulfate 200 MG (1)

Hydroxychloroquine Sulfate 200 MG [Plaquenil] (1)

Hydroxychloroquine Sulfate 200 milligram (mg) Tab (1)

Hydroxychloroquine Sulfate 400 mg twice a day (1)

Hydroxychloroquine Sulfate 600 mg once a day (1)

Hydroxychloroquine Sulfate 600 mg twice a day (1)

Hydroxychloroquine Sulfate and Azithromycin (1)

Hydroxychloroquine Sulfate and Folic Acid (1)

Hydroxychloroquine and Azithromycin (1)

Hydroxychloroquine and azithromycin treatment (1)

Hydroxychloroquine and azithromycin treatment arm. (1)

Hydroxychloroquine as post exposure prophylaxis (1)

Hydroxychloroquine in combination of Azithromycin (1)

Hydroxychloroquine plus Nitazoxanide (1)

Hydroxychloroquine plus standard preventive measures (1)

Hydroxychloroquine, Azithromycin (1)

Hydroxychloroquine, Clindamycin (1)

Hydroxychloroquine, Clindamycin, Primaquine - high dose. (1)

Hydroxychloroquine, Clindamycin, Primaquine - low dose. (1)

Hydroxychloroquine, Doxycycline (1)

Hyperbaric oxygen (1)

Hyperbaric oxygen therapy (1)

Hyperbaric oxygen treatment (HBOT) i.e. inhalation of pressurized oxygen delivered by a hyperbaric chamber (drug/device) (1)

Hyperimmune plasma (1)

IC14, a monoclonal antibody against CD14 (1)

ICU treatment (1)

IV Deployment Of cSVF In Sterile Normal Saline IV Solution (1)

IgM and IgG diagnostic kits to SARS-CoV-2 (1)

Imatinib tablets (1)

Immunoglobulin of cured patients (1)

Immunological profiling (1)

Impact Event Score (1)

Impact of Event Scale-Revised (1)

Individualised Ayurveda (1)

Indomethacin (1)

Information-only intervention (1)

Inhaled Supplemental Oxygen (1)

Inhaled beclomethasone (1)

Inhaled budesonide (1)

Inhaled nitric oxide gas (1)

Injection and infusion of LV-SMENP-DC vaccine and antigen-specific CTLs (1)

Injective placebo (1)

Insulin regimen (1)

Interferon-Alpha2B (1)

Interferon-Beta (1)

Interferon-β 1a (1)

Interferon-β1a (1)

Intermediate dose thromboprophylaxis (1)

Intermittent prone positioning instructions (1)

Internet-delivered cognitive behavior therapy (ICBT) for dysfunctional worry related to the Covid-19 pandemic (1)

Intraosseous access (1)

Intravenous Immunoglobulin (1)

Intravenous access (1)

Intravenous drug (1)

Intravenous saline injection (Placebo) (1)

Isoprinosine (1)

Isotonic saline 0.9% (1)

Isotretinoin Only Product in Oral Dose Form (1)

Isotretinoin(Aerosolized 13 cis retinoic acid) +standard treatment (1)

Ivermectin plus Nitazoxanide (1)

Ivermectine (1)

JNJ-53718678 (1)

Kerecis Oral and Nasal Spray (1)

Ketogenic diet (1)

Laboratory Biomarker Analysis (1)

Lactated ringer's solution or sterile saline (1)

Leflunomide (1)

Levamisole and Isoprinosine (1)

Liberase Enzyme (Roche) (1)

Linagliptin (1)

Linagliptin 5 MG (1)

Liquid Peanut Extract (1)

Liver injury (1)

Loop mediated isothermal amplification COVID-19 (1)

Lopinavir / Ritonavir Pill (1)

Lopinavir / Ritonavir plus Ribavirin (1)

Lopinavir / ritonavir tablets combined with Xiyanping injection (1)

Lopinavir / ritonavir, alpha-interferon nebulization (1)

Lopinavir 200Mg/Ritonavir 50Mg Tab (1)

Lopinavir and Ritonavir Tablets (1)

Lopinavir and ritonavir (1)

Lopinavir/Ritonavir (1)

Lopinavir/ritonavir treatment (1)

Low Dose Radiation Therapy (1)

Low dose CT (1)

Low-dose chloroquine/hydroxychloroquine (1)

MRx-4DP0004 (1)

MSCs-derived exosomes (1)

MVA-MERS-S_DF1 - High Dose (1)

MVA-MERS-S_DF1 - Low Dose (1)

Machine learning model (1)

Macrolide administered for 3-5 days (1)

Macrolide administered for up to 14 days (1)

Matched Placebo (1)

Matched Placebo Hydroxychloroquine (1)

Matrix-M Adjuvant (1)

Measles-Mumps-Rubella Vaccine (1)

Medical Mask (1)

Medical/surgical mask (1)

Mefloquine + azithromycin + / - tocilizumab (1)

Melatonin 2mg (1)

Meplazumab for Injection (1)

Mesenchymal cells (1)

Methylprednisolone Sodium Succinate (1)

Microcannula Harvest Adipose Derived tissue stromal vascular fraction (tSVF) (1)

Mid dose chloroquine or hydroxychloroquine (1)

Mindfulness session(s) (1)

Mindfulness-based "STOP touching your face" practice (1)

Minocycline (1)

Monitoring Visit - Baseline (1)

Monitoring Visit - Week 4 (1)

Monitoring Visit - Week 8 (1)

Montelukast Oral Granules (1)

Moxifloxacin or Levofloxacin (1)

Multifrequency Bioimpedance Spectroscopy (1)

Multiple Doses of Anti-SARS-CoV-2 convalescent plasma (1)

MuscleSound Ultrasound (1)

N-acetylcysteine+ Fuzheng Huayu Tablet (1)

N-acetylcysteine+Placebo (1)

N95 Respirator (1)

N95 respirator (1)

NA (no intervention) (1)

NIO® (Intraosseous access) (1)

NK cells,IL15-NK cells,NKG2D CAR-NK cells,ACE2 CAR-NK cells,NKG2D-ACE2 CAR-NK cells (1)

NO intervention planned due to the observational study design only a diagnostic testing (1)

NSS Saline Placebo (1)

Nafamostat Mesilate (1)

Naso pharyngeal swab (1)

Natural Honey (1)

New QIAstat-Dx fully automatic multiple PCR detection platform (1)

New screening strategy (1)

Next generation Sequencing (NGS) analysis (1)

Niclosamide (1)

Nigella Sativa / Black Cumin (1)

Nintedanib 150 MG (1)

Nitazoxanide 500 MG (1)

Nitazoxanide Tablets (1)

Nitric Oxide 0.5 % / Nitrogen 99.5 % Gas for Inhalation (1)

Nivolumab Injection (1)

No intervention (survey study for medical doctors). (1)

No intervention, observational study (1)

No special intervention (1)

Non Extracorporeal Membrane Oxygenation (1)

Non-Interventional (1)

Non-convalescent Plasma (control plasma) (1)

Normal (9%) Saline (1)

Normal Saline Infusion + Maximal intensive care (1)

Normal saline (1)

Normobaric oxygen therapy (1)

Nutrition support (1)

Observation of behavior and COVID-19 infection will be conducted. (1)

Observation of patients with known, suspected, or at risk for COVID-19 infection (1)

Observational (registry) (1)

Observational Study (1)

Observational only (1)

Odd/Even birth year intervention groups (1)

Omeprazole 20mg (1)

Online Questionnaire (1)

Online Survey (1)

Oral placebo (1)

Other drugs (1)

Others(No intervention) (1)

Outpatient MRI (1)

Oxygen Therapy (1)

Oxygen-ozone therapy, probiotic supplementation and Standard of care (1)

Ozone auto-hemotherapy (1)

PD-1 blocking antibody+standard treatment (1)

PHQ-9 (9-item Patient Health Questionnaire) (1)

PROTECTIVE VENTILATION (1)

PSS (Perceived Stress Scale) (1)

Pacebo: Calcium citrate (1)

Pathogen-specific aAPC (1)

Patient management suffering of coronavirus infection (1)

Patient sampling (1)

Patients with the treatment agains COVID19 (1)

Peginterferon Lambda-1A (1)

Peginterferon Lambda-1a (1)

Peginterferon lambda alfa-1a subcutaneous injection (1)

Pegylated interferon lambda (1)

Pembrolizumab (MK-3475) (1)

Peripheral blood draw (1)

Personalized health education (1)

Phosphate buffered saline Placebo (1)

Physical Exam (1)

Physical Therapy (1)

Physiological serum (1)

Piclidenoson (1)

Piperacillin-tazobactam (1)

Placebo (Plasma-Lyte 148) (1)

Placebo + Placebo (1)

Placebo 250 cc 24 hours continuous infusion for 15 days (1)

Placebo Glycerin SLIT (1)

Placebo Vaccine (1)

Placebo for Azithromycin (1)

Placebo for Hydroxychloroquine (1)

Placebo of Hydroxychloroquine (1)

Placebo of LPV/r Tablets (1)

Placebo oral capsule (1)

Placebo plus standard preventive measures (1)

Placebo solution (1)

Placebo: Emtricitabine/tenofovir disoproxil Placebo (1)

Placebo: Hydroxychloroquine (1)

Plaquenil 200Mg Tablet (1)

Plasma Adsorption Cartridge (1)

Plasma Donation (1)

Point-of-Care Ultrasonography (POCUS) (1)

Polysomnography (1)

Postpartum women under investigation for Coronavirus or diagnosed with COVID-19 (1)

Postural Positioning (1)

Povidone-Iodine (1)

Povidone-Iodine 0.5% (1)

Povidone-Iodine 2% (1)

Powered Air purifying respirator (1)

Practice details (1)

Pregnant women under investigation for Coronavirus or diagnosed with COVID-19 (1)

Presatovir placebo (1)

Prone Positioning (1)

Prone position (1)

Prone positioning (PP) (1)

Prospective oberservational registry (1)

Prototype swab (1)

Psychological and physical rehabilitation based humanistic care (1)

Public Health England Gold Standard (1)

Pulmonary Physiotherapy Techniques (1)

Pulmonary ultrasound (1)

Pyridostigmine Bromide (1)

Q-NRG Metobolic Cart Device (1)

Qualitative interviews (in 40 patients : 20 with COVID-19 and 20 without COVID-19) (1)

Quality of Life (1)

Questionnaire by phone call (1)

Questionnaire with precaution information (1)

Questionnaires, spirometry (1)

Quick Defense (1)

Radiological Detection (1)

Ramipril 2.5 MG Oral Capsule (1)

Random Donor Plasma (1)

Rapid diagnostics using Anyplex TMII RV16 Detection (1)

Rapid molecular test (1)

Ravulizumab (1)

Recombinant Human Interferon α2b Spray (1)

Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) (1)

Recombinant S protein SARS vaccine (1)

Recombinant human angiotensin-converting enzyme 2 (rhACE2) (1)

Recombinant human interferon α1β (1)

Recombinant novel coronavirus vaccine (Adenovirus type 5 vector) (1)

Recombinase aided amplification (RAA) assay (1)

Registery Data Collection (1)

Remestemcel-L (1)

Remestemcel-L® (1)

Remote consultation (1)

Retrospective data collection (1)

Reverse-transcription polymerase chain reaction (RT-PCR) (1)

Risk of MERS infection (1)

Ritonavir+Oseltamivir (1)

Rivaroxaban (1)

Rivaroxaban 2.5 MG (1)

RoActemra iv (1)

RoActemra sc (1)

Routine care for COVID-19 patients (1)

Ruxolitinib administration (1)

Ruxolitinib plus simvastatin (1)

SAMBA II (Diagnostic for the Real World) (1)

SARS-CoV-2 IgG Antibody Testing Kit (1)

SARS-CoV-2 non-immune Plasma (1)

SARS-CoV-2 rS (1)

SARS-CoV-2 viral composition (1)

SARS-Cov-2 infection (1)

SARS-Cov2 testing (1)

SLEDD with a L-MOD (1)

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Covid 19 Research using Clinical Trials (Home Page)

Non-convalescent Plasma (control plasma)Wiki

Developed by Shray Alag

Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation

Correlated Drug Terms (1)

	Name (Synonyms)	Correlation
drug226	Convalescent Plasma (anti-SARS-CoV-2 plasma) Wiki	1.00

Correlated MeSH Terms (2)

	Name (Synonyms)	Correlation
D045169	Severe Acute Respiratory Syndrome NIH	0.07
D018352	Coronavirus Infections NIH	0.06

Correlated HPO Terms (0)

	Name (Synonyms)	Correlation

There is one clinical trial.

Clinical Trials

1 A Phase 2, Randomized Clinical Trial to Evaluate the Efficacy and Safety of Human Anti-SARS-CoV-2 Convalescent Plasma in Severely Ill Adults With COVID-19

This randomized blinded phase 2 trial will assess the efficacy and safety of Anti-SARS-CoV-2 convalescent plasma among adults with severe COVID-19. Adults ≥18 years of age may participate. A total of 105 eligible subjects will be randomized in a 2:1 ratio to receive either high-titer anti-SARS-CoV-2 plasma or non-convalescent fresh frozen plasma (control plasma).

NCT04359810 SARS-CoV Infection Biological: Convalescent Plasma (anti-SARS-CoV-2 plasma) Biological: Non-convalescent Plasma (control plasma)

MeSH:Coronavirus Infections Severe Acute Respiratory Syndrome

Primary Outcomes

Description: The efficacy of treatment will be determined by determining the time-to-clinical improvement, defined as the time from randomization to either an improvement of one point on a seven-category ordinal scale or alive discharge from the hospital, whichever comes first.

Measure: Time to Improvement

Time: Up to 28 days

Secondary Outcomes

Description: Compare the rates of SARS-CoV-2 PCR positivity (RT PCR) amongst the anti-SARS-CoV-2 convalescent plasma and non-convalescent plasma groups.

Measure: Rate of SARS-CoV-2 PCR Positivity

Time: Up to 14 days

Description: Compare the duration of SARS-CoV-2 PCR positivity (RT PCR) amongst the anti-SARS-CoV-2 convalescent plasma and non-convalescent plasma groups.

Measure: Duration of SARS-CoV-2 PCR Positivity

Time: Up to 14 days

Description: Compare duration of need for supplemental oxygen and/or mechanical ventilation amongst the anti-SARS-CoV-2 convalescent plasma and non-convalescent plasma groups.

Measure: Duration of Need for Supplemental Oxygen

Time: Up to 28 days

Description: Compare duration of hospitalization amongst the anti-SARS-CoV-2 convalescent plasma and non-convalescent plasma groups.

Measure: Duration of Hospitalization

Time: Up to 28 days

Description: Compare in-hospital and 28-day mortality amongst the anti-SARS-CoV-2 convalescent plasma and non-convalescent plasma groups.

Measure: In-hospital 28-day Mortality Rate

Time: Up to 28 days

No related HPO nodes (Using clinical trials)