Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug4551 | life questionnaires Wiki | 1.00 |
| drug4687 | questionnaire Wiki | 0.38 |
Navigate: Correlations HPO
There is one clinical trial.
This prospective randomized single Center study investigates to what extent the physical elimination of the inflammatory mediators using the CytoSorb adsorber reduces the morbidity of severely and critically ill patients with Covid-19.
Description: Percentage of patients with a significant stabilization of hemodynamics ("shock reversal"), defined as a significant reduction of the noradrenaline dose (≤ 0.05 µg/kg/min) while maintaining mean arterial pressure ≥ 65 mmHg for at least 24 hours compared to control group
Measure: Percentage of patients with a significant stabilization of hemodynamics for at least 24 hours Time: 24 hoursDescription: Change in organ dysfunction based on "Sequential Organ Failure Assessment" (SOFA) Score The SOFA score is made of 6 variables, each representing an organ system. Each organ system is assigned a point value from 0 (normal) to 4 (high degree of dysfunction/failure) The worst physiological variables were collected serially every 24 hours of a patient's ICU admission. The "worst" measurement was defined as the measure that correlated to the highest number of points. The SOFA score ranges from 0 to 24.
Measure: Change in organ dysfunction Time: 10 daysDescription: Improving lactate clearance by lowering serum lactate levels
Measure: Lactate clearance Time: 10 daysDescription: Time with need for renal replacement therapy
Measure: Renal replacement therapy Time: 10 daysDescription: Time with Need for Extracorporeal Membrane Oxygenation
Measure: Extracorporeal Membrane Oxygenation Time: 10 daysDescription: ICU length of stay
Measure: ICU length of stay Time: 90 daysDescription: Time on mechanical ventilation
Measure: Time on mechanical ventilation Time: 10 daysDescription: Cumulative catecholamine dose
Measure: Cumulative catecholamine dose Time: 10 daysDescription: Overall and ICU mortality
Measure: Overall and ICU mortality Time: 90 daysDescription: Change of plasma Interleukin-6 (IL6) level
Measure: Change of plasma Interleukin-6 (IL6) level Time: 10 daysDescription: Change of plasma Interleukin-10 (IL10) level
Measure: Change of plasma Interleukin-10 (IL10) level Time: 10 daysDescription: Change of plasma Procalcitonin (PCT) level
Measure: Change of plasma Procalcitonin (PCT) level Time: 10 daysDescription: Change of HLA-DR (Human Leukocyte Antigen - DR isotype) level of monocytes
Measure: Change of HLA-DR level Time: 10 daysDescription: Change of TNF-alfa level (Tumor Necrosis Factor alpha) level after LPS (Lipopolysaccharides) stimulation as sign of monocytic immunocompetence
Measure: Change of TNF alpha level after ex-vivo stimulation Time: 10 daysAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports