Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
Name (Synonyms) | Correlation | |
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drug4308 | Withings ScanWatch Wiki | 0.71 |
drug4367 | alpha one antitrypsin inhalation Wiki | 0.71 |
Name (Synonyms) | Correlation | |
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D016638 | Critical Illness NIH | 0.09 |
D045169 | Severe Acute Respiratory Syndrome NIH | 0.03 |
D018352 | Coronavirus Infections NIH | 0.03 |
Name (Synonyms) | Correlation |
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Navigate: Correlations HPO
There are 2 clinical trials
This is an observational study exploring the levels of mobility and rehabilitation in patients admitted to critical care with a confirmed diagnosis of COVID-19
Description: Highest level of mobility achieved at the point of ICU discharge
Measure: Mobility level Time: At ICU discharge, an average of 3 weeksDescription: Time taken to first mobilise, defined as sitting on the edge of the bed or higher
Measure: Time taken to first mobilise Time: during ICU admission, up to 3 weeksDescription: Discharged to home, home with rehab, or a community rehab facility
Measure: Discharge location Time: Hospital discharge, up to 2 monthsProblems such as breathlessness, exercise intolerance and loss of peripheral muscle strength can be observed in individuals who have been diagnosed with COVID19 and have been discharged. In our study, it was aimed to investigate the effect of telerehabilitation physical therapy intervention to these cases by using videoconferencing method on the physical condition of the cases.
Description: The mMRC Dyspnea Scale is best used to establish baseline functional impairment due to dyspnea attributable to respiratory disease; tracking the mMRC over time or with therapeutic interventions is of less certain clinical utility.The severity of dyspnea is rated on a scale of 0 to 4. "O" means no dyspnea perception, "4" means severe dyspnea perception.
Measure: Modified Medical Research Council Dyspnea Score Time: Baseline to 6 weeksDescription: The Timed "Up and Go" (TUG) Test measures, in seconds, the time taken by an individual to stand up from a standard arm chair (approximate seat height of 46 cm, arm height 65 cm), walk a distance of 3 meters (approximately 10 feet), turn, walk back to the chair, and sit down. Normal healthy elderly usually complete the task in 10 seconds or less. Very frail or weak elderly with poor mobility may take 2 minutes or more. Clinical guide: <10 seconds = normal <20 seconds = good mobility, can go out alone, mobile without a gait aid <30 seconds = problems, cannot go outside alone, requires a gait aid A score of more than or equal to 14 seconds has been shown to indicate high risk of falls.
Measure: Timed up and go test Time: Baseline to 6 weeksDescription: Visual analog scale to assess the pain on a horizontal, non-calibrated line of 100 mm, ranging from very low (0) to very high (100) score.
Measure: Visual analog scale to assess the pain severity Time: Baseline to 6 weeksDescription: The Short Physical Performance Battery (SPPB) is comprised of 3 tasks: a standing balance test (side by side, semi-tandem and tandem), a 4-m habitual gait speed, and 5 sit to stand from a chair. Each task is scored (based on time) from 0-4 points. The total score is 12 points and this represents the highest performance. It can be easily performed at home via video conferencing
Measure: The Short Physical Performance Battery (SPPB) Time: Baseline to 6 weeksDescription: Visual analog scale to assess the fatigue severity on a horizontal, non-calibrated line of 100 mm, ranging from very low (0) to very high (100) score.
Measure: Visual analog scale to assess the fatigue severity Time: Baseline to 6 weeksDescription: This is a 21-item self-assessment scale designed by Aaron Beck in 1961 to measure the risk and level of depression.
Measure: BECK depression inventory Time: Baseline to 6 weeksDescription: The SGRQ ranges from 0 (no impairment of quality of life) to 100 (highest impairment of quality of life)
Measure: Saint George Respiratory Questionnaire Time: Baseline to 6 weeksAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports