Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
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drug3124 | Prospective study with two measurement points investigating the impact of viral mitigation protocols on parental burnout Wiki | 1.00 |
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Navigate: Correlations HPO
There is one clinical trial.
Prospective multicenter observational no-profit study evaluating the impact of ERAS program items adherence rates on patient-reported outcomes (PRO) and return to intendend oncologic therapy (RIOT) after colorectal resection. Prospective enrollment from November 2020 to October 2021 in 60 Italian surgical centers. All patients undergoing elective colorectal surgery with anastomosis will be included in a prospective database after written informed consent. A total of 3,000 patients is expected based on a mean of 50 cases per center.
Description: Quality of life questionnaire based on five dimensions: mobility, self-care, usual activities, pain/discomfort and anxiety/depression. Each dimension has 5 levels: no problems, slight problems, moderate problems, severe problems and extreme problems. Scores ranging from 5 (worst) to 125 (best)
Measure: Change in patient-reported outcome measure #1; Health Questionnaire; Euro-QoL Group EQ-5D-5L™; Time: Before the operation, postoperative day 5, 4 to 6 weeks after the operationDescription: Specific quality of life questionnaire for patients submitted to GI surgery: based on 24 questions with scores ranging from 0 (best) to 10 (worst); total score from 0 (best) to 240 (worst)
Measure: Change in patient-reported outcome measure #2; Health Questionnaire: MD Anderson Symptom Inventory for gastrointestinal surgery patients (MDASI-GI) Time: Before the operation, postoperative day 5, 4 to 6 weeks after the operationDescription: Specific quality of life questionnaire for patients with colorectal cancer. Scores ranging form 0 (worst) to 144 (best).
Measure: Change in patient-reported outcome measure #3; Health Questionnaire Functional Assessment of Cancer Therapy - Colorectal® (FACT-C) Time: Before the operation, postoperative day 5, 4 to 6 weeks after the operationDescription: Number of patients eligible for adjuvant therapy after surgery for colorectal cancer that receive appropriate treatment starting within 8 weeks after the operation
Measure: Return to intended oncologic therapy (RIOT) Time: 8 weeks after the operationDescription: number of anastomotic leakage
Measure: Anastomotic leakage rate Time: within 8 weeks from operationDescription: number of any perioperative adverse event graded according to Clavien-Dindo
Measure: Overall morbidity rate Time: within 8 weeks from operationDescription: number of Clavien-Dindo grade >II perioperative adverse events
Measure: Major morbidity rate Time: within 8 weeks from operationDescription: Total number of days spent in the hospital (including any readmission)
Measure: Length of hospital stay (LOS) Time: within 8 weeks from operationAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports