Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
| Name (Synonyms) | Correlation | |
|---|---|---|
| D014652 | Vascular Diseases NIH | 0.50 |
| D006331 | Heart Diseases NIH | 0.27 |
| D012120 | Respiration Disorders NIH | 0.23 |
| Name (Synonyms) | Correlation |
|---|
Navigate: Correlations HPO
There is one clinical trial.
Contactless and widely available health monitoring technologies are of growing interest in the context of the worldwide COVID-19 pandemic. Remote photoplethysmography (rPPG) is a well-studied technology that interprets variations in skin colour related to blood flow which, when analysed with complex mathematical algorithm, generates vital sign readings. This technology has been refined and embedded in a smartphone app designed to acquire heart rate, respiratory rate and oxygen saturation using a front-facing smartphone camera. Preliminary data comparing the accuracy of smartphone rPPG readings with conventional vital sign monitor readings are promising; however, less than 5% of the population studied in the app development phase had oxygen saturation levels below 95% making it impossible to ensure reliability in these populations. The goal of this study is to compare readings acquired using this rPPG app with the readings from hospital grade, Health Canada approved vital signs monitors used in healthcare settings with a focus on subject with low oxygen saturations. We will also study other sociodemographic and clinical features that may influence the accuracy of the readings. This will be achieved by recruiting consenting adults presenting to care in acute care settings and a designated COVID outpatient clinic. Vital signs will be acquired using the rPPG app and conventional hospital vital sign monitors simultaneously. Readings will be repeated within 2-5 minutes when time permits. Statistical analysis will be performed to analyze the findings and determine the accuracy and precision of the rPPG app readings. It is expected that the vital sign readings acquired with the rPPG app will be almost identical to those acquired using hospital-grade monitors for all subjects regardless of age, gender, skin colour, COVID status and relevant comorbidities.
Description: Accuracy of rPPG heart rate compared to conventional vital sign monitor heart rate readings. Comparison of each paired reading.
Measure: Accuracy of rPPG heart rate Time: immediate; paired readingDescription: Accuracy of rPPG oxygen saturation compared to conventional vital sign monitor oxygen saturation readings. Comparison of discrepancy within each paired reading set.
Measure: Accuracy of rPPG oxygen saturation Time: immediate; paired readingDescription: Accuracy of rPPG respiratory rate compared to manual counting of respiratory rate over 60 seconds. Comparison of discrepancy within each paired reading set.
Measure: Accuracy of rPPG respiratory rate Time: immediate; paired readingDescription: Comparison of rPPG heart rate results obtained on a given patient on serial readings within 2 minutes of each other.
Measure: Reproducibility of rPPG heart rate readings Time: 2-5 minutesDescription: Comparison of rPPG oxygen saturation results obtained on a given patient on serial readings within 2 minutes of each other.
Measure: Reproducibility of rPPG oxygen saturation readings Time: 2-5 minutesDescription: Comparison of rPPG respiratory rate results obtained on a given patient on serial readings within 2 minutes of each other.
Measure: Reproducibility of rPPG respiratory rate readings Time: 2-5 minutesDescription: Analysis of accuracy of rPPG vital sign readings when stratified by oxygen saturation per conventional monitors stratified as follows: 95-100%; 90-94%; 85-89%; Less than 85%
Measure: Accuracy of rPPG readings by oxygen saturation level Time: immediate; stratified analysisDescription: Analysis of accuracy of rPPG vital sign readings when stratified by skin colour per the Fitzpatrick scale
Measure: Accuracy of rPPG readings by skin colour Time: immediate; stratified analysisDescription: Analysis of accuracy of rPPG vital sign readings when stratified for gender
Measure: Accuracy of rPPG readings by gender Time: immediate; stratified analysisDescription: Analysis of accuracy of rPPG vital sign readings when stratified by age group
Measure: Accuracy of rPPG readings by age Time: immediate; stratified analysisDescription: Analysis of accuracy of rPPG vital sign readings when stratified for COVID, respiratory conditions, cardiac conditions and vascular conditions.
Measure: Accuracy of rPPG readings by comorbidity Time: immediate; stratified analysisAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports