Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
| Name (Synonyms) | Correlation | |
|---|---|---|
| D055959 | Intervertebral Disc Degeneration NIH | 0.71 |
| Name (Synonyms) | Correlation | |
|---|---|---|
| HP:0008419 | Intervertebral disc degeneration HPO | 0.71 |
Navigate: Correlations HPO
There is one clinical trial.
The purpose of this study is to evaluate the safety and efficacy of KUR-113 Bone Graft (TGplPTH1-34 in fibrin) compared to local autograft for the treatment of Degenerative Disk Disease (DDD).
Description: Evidence of bridging trabeculae or continuous bony connection between superior and inferior vertebral body on CT-scan as determined by an independent radiology expert panel (IREP).
Measure: Radiographic interbody fusion Time: Month 12 post-surgeryDescription: Radiographic interbody fusion using CT-scans, functional outcome (decrease of 15 points or more on Oswestry Disability Index (ODI)) and no post-surgical intervention to aid fusion or replace any of the spinal implants.
Measure: Composite Endpoint Time: Month 6 and Month 12 post-surgeryDescription: Determined by IREP using CT-scans
Measure: Radiographic interbody fusion Time: Month 6 post-surgeryDescription: Determined by IREP using CT-scans
Measure: Radiographic posterolateral fusion Time: Month 6 and Month 12 post-surgeryDescription: Change from baseline
Measure: ODI Time: Week 6, Month 3, Month 6, Month 12, and Month 24 post-surgeryDescription: Change from baseline using Visual Analogue Scale (VAS). VAS is scored from 0 to 100 with higher numbers being a worse outcome than a lower number.
Measure: Leg Pain Time: Initial discharge from hospital (on average 3 days post-surgery), Week 6, Month 3, Month 6, Month 12, and Month 24 post-surgeryDescription: Change from baseline using Visual Analogue Scale (VAS). VAS is scored from 0 to 100 with higher numbers being a worse outcome than a lower number.
Measure: Back Pain Time: Initial discharge from hospital (on average 3 days post-surgery), Week 6, Month 3, Month 6, Month 12, and Month 24 post-surgeryDescription: Revisions, re-operations, removals, supplemental fixations, or any other procedure that adjusts or in any way removes part of the original implant configuration with or without replacement of the components
Measure: Number of Secondary Interventions Time: Up to Month 24 post-surgeryAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports