Covid 19 Research Clinical Trials by Shray Alag

CytoSorb 300 mL device

Developed by Shray Alag, The Harker School
Sections: Correlations, Clinical Trials, and HPO

Correlations computed by analyzing all clinical trials.

Correlated Drug Terms (1)

	Name (Synonyms)	Correlation
drug1305	EHR-based Clinician Jumpstart Wiki	1.00

Correlated MeSH Terms (14)

	Name (Synonyms)	Correlation
D016491	Peripheral Vascular Diseases NIH	0.58
D058729	Peripheral Arterial Disease NIH	0.50
D014652	Vascular Diseases NIH	0.50

	Name (Synonyms)	Correlation
D008103	Liver Cirrhosis, NIH	0.50
D009362	Neoplasm Metastasis NIH	0.45
D051437	Renal Insufficiency, NIH	0.41
D007676	Kidney Failure, Chronic NIH	0.38
D006333	Heart Failure NIH	0.29
D008175	Lung Neoplasms NIH	0.29
D017563	Lung Diseases, Interstitial NIH	0.27
D002908	Chronic Disease NIH	0.27
D029424	Pulmonary Disease, Chronic Obstructive NIH	0.26
D008171	Lung Diseases, NIH	0.20
D009369	Neoplasms, NIH	0.17

Correlated HPO Terms (9)

	Name (Synonyms)	Correlation
HP:0001395	Hepatic fibrosis HPO	0.50
HP:0000083	Renal insufficiency HPO	0.41
HP:0004950	Peripheral arterial stenosis HPO	0.38

	Name (Synonyms)	Correlation
HP:0001635	Congestive heart failure HPO	0.29
HP:0100526	Neoplasm of the lung HPO	0.29
HP:0006515	Interstitial pneumonitis HPO	0.27
HP:0006510	Chronic pulmonary obstruction HPO	0.26
HP:0002088	Abnormal lung morphology HPO	0.20
HP:0002664	Neoplasm HPO	0.17

Clinical Trials

Navigate: Correlations HPO

There is one clinical trial.

1 Registry of CytoSorb Therapy in COVID-19 ICU Patients (CTC REGISTRY): Registry of Patient-level Clinical Data on CytoSorb Hemoadsorption Provided Via Integration of the CytoSorb Device Into Extracorporeal Membrane Oxygenation (ECMO), Continuous Renal Replacement Therapy (CRRT), or Hemoperfusion Extracorporeal Circuits in COVID-19 ICU Patients

The CTC Registry collects patient-level clinical data on CytoSorb hemoadsorption provided to COVID-19 ICU patients via integration of the CytoSorb device into ECMO, CRRT, or hemoperfusion extracorporeal circuits under the FDA Emergency Use Authorization for this CytoSorb device use. The intent of the registry is to gain understanding on how CytoSorb hemoadsorption provides clinical benefit to COVID-19 ICU patients.

NCT04391920

Conditions

COVID-19

Interventions

Device: CytoSorb 300 mL device

Primary Outcomes

Measure: ICU mortality

Time: From the date of start of CytoSorb use until the date of ICU discharge or date of death, whichever comes first, assessed up to 1 year

Secondary Outcomes

Measure: Duration of ECMO after start of CytoSorb

Time: From the date of start of CytoSorb use until the date of cessation of ECMO or date of death, which ever comes first, assessed up to 1 year

Measure: Duration of mechanical ventilatory support after start of CytoSorb

Time: From the date of start of CytoSorb use until the date of cessation of mechanical ventilatory support or date of death, which ever comes first, assessed up to 1 year

Measure: Duration of pharmacologic hemodynamic support after start of CytoSorb

Time: From the date of start of CytoSorb use until the date of cessation of pharmacologic hemodynamic support or date of death, which ever comes first, assessed up to 1 year

Measure: Change in serum concentrations of inflammatory biomarkers after start of CytoSorb

Time: From the day before start of CytoSorb use until the day after cessation of CytoSorb use

No related HPO nodes (Using clinical trials)

HPO

Alphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials

No related HPO nodes (Using clinical trials)

Reports

Data processed on September 26, 2020.

An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

Drug Reports MeSH Reports HPO Reports

CovidResearchTrials

Report Sections

See All Reports

CytoSorb 300 mL device

Correlations computed by analyzing all clinical trials.

Correlated Drug Terms (1)

Correlated MeSH Terms (14)

Correlated HPO Terms (9)

Clinical Trials

NCT04391920

Conditions

Interventions

Primary Outcomes

Secondary Outcomes

No related HPO nodes (Using clinical trials)

HPO

No related HPO nodes (Using clinical trials)

Reports

Interventions

MeSH

HPO

All Terms

Google Colab