Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug4280 | Wait-list control Wiki | 1.00 |
| drug4761 | survey Wiki | 0.38 |
| Name (Synonyms) | Correlation |
|---|
Navigate: Correlations HPO
There is one clinical trial.
We are evaluating the effects of an online single-session mental health intervention (the Common Elements Toolbox; COMET). To evaluate COMET, we are conducting a randomized controlled trial with Indian college students. Students will be randomized to the COMET condition or to a wait-list control condition. Primary outcome measures (depressive symptoms, anxiety symptoms, and subjective well-being) will be measures at two weeks post-intervention, four weeks post-intervention, and twelve weeks post-intervention. We will evaluate COMET as a universal intervention (using the full sample) and as a targeted intervention (analyzing those who reported elevated depressive symptoms or anxiety symptoms at baseline).
Description: Depression questionnaire. Scores range from 0 to 27. Lower scores indicate less depression.
Measure: Change in Patient Health Questionnaire-9 (PHQ-9) Time: Up to 12 weeks post-interventionDescription: Anxiety questionnaire. Total scores range from 0-21. Lower scores indicate less anxiety.
Measure: Change in Generalized Anxiety Disorder Screener-7 (GAD-7) Time: Up to 12 weeks post-interventionDescription: Subjective Well-being questionnaire. Total scores range from 7 to 35. Higher values indicate higher well-being scores.
Measure: Change in the Short Warwick-Edinburgh Mental Well-being Scale (SWEMWBS) Time: Up to 12 weeks post-interventionDescription: Questionnaire measuring the acceptability of an intervention. Acceptability refers to the perception that a given treatment is agreeable or satisfactory. The total score ranges from 4 to 20. Higher scores indicate higher acceptability ratings.
Measure: Ratings on the Acceptability of Intervention Measure (AIM) Time: Immediately after the interventionDescription: Questionnaire measuring the appropriateness of an intervention. Appropriateness refers to the perceived fit or relevance of an intervention. The total score ranges from 4 to 20. Higher scores indicate higher appropriateness.
Measure: Ratings on the Intervention Appropriateness Measure (IAM) Time: Immediately after the interventionDescription: Participants answered questions relating to each module's mechanism of change on a 7-point Likert Scale, from "strongly disagree" to "strongly agree". Specifically, we asked participants: How capable they feel about managing negative thoughts If they will intentionally spend time doing activities they enjoy If they will notice and appreciate good things
Measure: Mechanisms of Change Time: Up to 12 weeks post-interventionDescription: 2 questions related to their ability to cope with stressors over the upcoming weeks (including challenges relating to COVID-19). Participants answered these questions on a 7-point Likert Scale, from "strongly disagree" to "strongly agree". Specifically, we asked participants: if they will be able to handle lifestyle changes due to the coronavirus, if the pandemic will have an extremely negative impact on their life.
Measure: Ability to Cope with COVID-19 Time: Up to 12 weeks post-interventionDescription: We asked participants three items to assess secondary control (Weisz et al., 2010). The items are scored on a 4-point Likert scale, ranging from 0 ("Very false") to 3 ("Very true"). The three items are: When something bad happens, I can find a way to think about it that makes me feel better. After a really hard day, I can make myself feel better by remembering some good things that happened. When bad things happen to me that I can't control, there are lots of things I can do to feel better. Higher scores indicate greater secondary control.
Measure: Secondary Control Time: Up to 12 weeks post-interventionDescription: Participants were asked to rate three items relating to the perceived utility of each module. Specifically, we asked participants: How helpful the module was How engaging the module was How much they will continue applying content from the module Higher scores indicate greater perceived utility.
Measure: Perceived Utility Time: Immediately after the interventionDescription: Questionnaire measuring positive affect and negative affect. Scores on the positive affect subscale range from 10-50, with higher scores representing higher levels of positive affect. Scores on the negative affect subscale range from 10-50, with lower scores representing lower levels of negative affect
Measure: Positive and Negative Affect Schedule Time: Up to 12 weeks post-interventionDescription: Questionnaire measuring perceived stress. Scores range from 0-16, with higher scores indicating greater stress.
Measure: Perceived Stress Scale-4 Time: Up to 12 weeks post-interventionDescription: Questionnaire measuring social connectedness. Scores range from 8 to 48, with higher scores indicating greater social connectedness.
Measure: The Social Connectedness Scale Time: Up to 12 weeks post-interventionAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports