Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug2908 | Pilot a rapid SARS-CoV-2 testing strategy Wiki | 0.26 |
| drug4522 | imPulse™ Una e-stethoscope Wiki | 0.26 |
| drug3427 | SARS-CoV-2 antibody test Wiki | 0.26 |
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug2885 | Philips Lumify Ultrasound System Wiki | 0.26 |
| drug997 | Community-driven messages to promote COVID-19 testing Wiki | 0.26 |
| drug570 | Biological/Vaccine: Angiotensin peptide (1-7) derived plasma Wiki | 0.26 |
| drug3624 | Simulation Airway Coaching Wiki | 0.26 |
| drug4503 | home spirometry Wiki | 0.26 |
| drug3275 | Rayaldee 30Mcg Extended-Release (ER) Capsule Wiki | 0.26 |
| drug725 | COVID 19 Convalescent Plasma Wiki | 0.26 |
| drug4725 | serology Wiki | 0.18 |
| drug2848 | Peginterferon beta-1a Wiki | 0.13 |
| drug2359 | Methotrexate Wiki | 0.13 |
| drug3516 | Saliva collection Wiki | 0.10 |
| drug2552 | Nitazoxanide Wiki | 0.07 |
| drug2916 | Placebo Wiki | 0.02 |
| Name (Synonyms) | Correlation | |
|---|---|---|
| D012004 | Rectal Neoplasms NIH | 0.26 |
| D018352 | Coronavirus Infections NIH | 0.11 |
| D003680 | Deglutition Disorders NIH | 0.11 |
| Name (Synonyms) | Correlation | |
|---|---|---|
| HP:0100743 | Neoplasm of the rectum HPO | 0.26 |
| HP:0002015 | Dysphagia HPO | 0.11 |
| HP:0000716 | Depressivity HPO | 0.05 |
Navigate: Correlations HPO
There are 15 clinical trials
We hypothesized: During the COVID-19 pandemic, the sleep quality of pregnant women decreases. During the COVID-19 epidemic, the stress level of pregnant women increases. During the COVID-19 epidemic, the level of physical activity of pregnant women decreases. Aims: The aim of the study is to determine the sleep quality, stress level and physical activity level of pregnant women who maintain the home quarantine during the COVID-19 pandemic.
Description: This measure assesses the types of intensity of physical activity and sitting time that people do as part of their daily lives are considered to estimate total physical activity in MET-min/week and time spent sitting. Walking = 3.3 METs Moderate Intensity = 4.0 METs Vigorous Intensity = 8.0 METs Total MET-minutes/week = Walk (METs*min*days) + Mod (METs*min*days) + Vig (METs*min*days) 1. Low: • No activity is reported OR • Some activity is reported but not enough to meet Categories 2 or 3. 2. Moderate: • 3 or more days of vigorous activity of at least 20 minutes per day OR • 5 or more days of moderate-intensity activity and/or walking of at least 30 minutes per day OR • 5 or more days of any combination of walking, moderate-intensity or vigorous intensity activities achieving a minimum of at least 600 MET-minutes/week. 3. High: • Vigorous-intensity activity on at least 3 days and accumulating at least 1500 MET-minutes/week
Measure: International Physical Activity Questionnaire Time: Baseline of the studyDescription: The Pittsburgh Sleep Quality Index (PSQI) is an effective instrument used to measure the quality and patterns of sleep. It differentiates "poor" from "good" sleep by measuring seven domains: subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, use of sleep medication, and daytime dysfunction over the last month.The client self rates each of these seven areas of sleep. Scoring of the answers is based on a 0 to 3 scale, whereby 3 reflects the negative extreme on the Likert Scale. A global sum of "5"or greater indicates a "poor" sleeper.
Measure: Pittsburgh Sleep Quality Index Time: Baseline of the studyDescription: The Perceived Stress Scale (PSS) is a 14-item self-report measure designed to assess "the degree to which situations in one's life are appraised as stressful. Each item is rated on a 5-point scale (0 = Never, 1 = Almost Never, 2 = Sometimes, 3 = Fairly Often, 4 = Very Often) and summed to create a total score. PSS-14 has strong internal consistency (α = .84 to .86) and good test-retest reliability (r = .85 over a 2-day period, r = .55 over a 6-week period.
Measure: Perceived Stress Scale Time: Baseline of the studyDescription: The Numeric Rating Scale (NRS) is the simplest and most commonly used numeric scale rates the pain from 0 (no pain) to 10 (worst pain).
Measure: Numerical Pain Rating Scale Time: Baseline of the studyThe investigators want to study how the exposure to the covid-19 pandemic affects attitudes towards science and vaccination, and how other general attitudes and values are affected.
Description: Survey
Measure: How vaccination and other attitudes are affected by COVID Time: Over last six monthsUse lay language. The Covid-19 pandemic hit France in March 2020 and stage 3 of the epidemic justified the introduction of national and unprecedented containment measures from March 17, 2020. The Montpellier CHU experienced peak hospitalizations of Covid-19 infections in late March. The estimate of the proportion of infected people in Occitania, South of France, for the 11th of May 2020 is 3.1% (95% CI: 1.9-5.9) for the Occitania region, to which Montpellier belongs. In the context of the Covid-19 epidemic, notably due to the absence of pharmacological or vaccine prophylaxis, barrier measures were of crucial importance, especially for exposed caregivers. These measures include an adaptation of individual behavior, the creation of a so-called "Covid" hospital, the wearing of specific equipment in all departments, the use in the rooms of Covid-19 patients of a gown, an apron, gloves, and a FFP2 type mask in the event of contact and sampling, protocolized and standardized bio-cleaning measures, a reorganization of the premises and the definition of specific circuits. In view of the second wave of the epidemic, estimating the effectiveness of the barrier measures is of major importance. The investigators therefore propose an evaluation of the effectiveness of these measures, by comparing the serological prevalence of infection among caregivers working directly in COVID units compared to caregivers working in services excluding the management of Covid-19 patients. Systematic evaluation in COVID-19 units of Sarc-Co-V2 infection will also be assessed, with naso-pharyngeal swabs.
Description: Proportion of caregivers and agents with a positive serodiagnosis in COVID units versus non-COVID units
Measure: Proportion of caregivers and agents with a positive serodiagnosis Time: 1 dayDescription: Proportion of caregivers and agents with a positive RT-PCR in COVID units versus non-COVID units
Measure: Proportion of caregivers and agents with a positive RT-PCR Time: 1 dayThis study will collect data on physical activity, food consumption, stress, sleep, and alcohol consumption habits both before and after the national emergency for COVID-19 was put into place. This will help identify the health behavior changes taking place due to the COVID-19 pandemic in the United States. Data on past and current health behaviors will be self-reported by participants via a single online survey. The retrospective health behavior questions will be the same quantitative questions as the current health behavior questions so a direct comparison can be made. There will be a couple qualitative questions to assess what each participant feels are the greatest barriers or impacts to their current health behaviors. Participants will be recruited via convenient sampling. Data collected in this study will show a decline in at least one healthy behavior after the United States national emergency for COVID-19.
Description: A negative shift in health behaviors when comparing individual health behavior before COVID-19 and the last 7-30 days. This behavior change may be in one or multiple health behaviors measured. A negative shift is indicated by overall decrease in physical activity time or intensity, increase in sitting time, increase in alcohol consumption days or drinks on drinking occasions, a decrease in fruit/vegetable consumption, or indication of consuming more food.
Measure: Health Behavior Change Regression Questionnaire Time: 1-3 monthsDentist exposed to coronavirus (COVID-19) may not have adequate access to personal protective equipment (PPE), safety procedures, and diagnostic protocols. Our objective will be to evaluate the reality and perceptions about personal safety among dentist in Egypt
Description: measure the personal protection measures used among dentist during Covid-19 pandemic through online Survey
Measure: Personal protection measures Time: one weekDescription: measure the personal protection measures used among dentist during Covid-19 pandemic through online Survey
Measure: impact of Covid-19 pandemic on type of face masks used in dental clinic Time: one weekThis study aims to identify the preference of the class modalities (classroom or online) in undergraduate and graduate students. Additionally, to explore if the presence of any mental state alterations such as depression or anxiety due to the COVID-19 pandemic can alter their perception of academic performance.
Description: This scale will explore the effort and confidence of the participants. The minimum score for each facet is 10, and the maximum score is 70.
Measure: Academic Self-Concept Scale Score Time: up to 3 monthsDescription: This inventory will be used to identify the presence and intensity of depressive disorders. The minimum score is 0, and the maximum score is 27.
Measure: PHQ-9 Score Time: up to 3 monthsDescription: This questionnaire will be used to evaluate the presence and intensity of anxiety disorders. The minimum score is 0, and the maximum score is 21.
Measure: GAD-7 Score Time: up to 3 monthsDescription: Students' preference of classroom or online classes.
Measure: Preference of teaching method Time: up to 3 monthsDescription: Students' perception of changes in their academic performance: got better, worse, or stayed the same.
Measure: Self perceived academic performance Time: up to 3 monthsDescription: Students' perception of changes in their grades: got better, worse, or stayed the same.
Measure: Academic grades changes Time: up to 3 monthsThe recent COVID-19 outbreak has put the health care workers on the frontline to interact and provide support to the patients. Based on previous disease outbreak-associated studies, it is evident that these individuals are at a high-risk of developing psychological distress such as burnout, anxiety, depression, and stress (BADS). Thus, the current study aims to evaluate the mental health outcomes of healthcare workers dealing with COVID-19 patients within Qatar and internationally, during and after the COVID-19 crisis. The participants will be divided into two groups: those working with COVID-19 patients and those not working with COVID-19 patients. The magnitude of symptoms of BADS will be assessed using electronic versions of the standardized questionnaires: Maslach Burnout Inventory (MBI-HSS), Hospital Anxiety and Depression Scale (HADS), Depression, Anxiety and Stress Scale (DASS-21), and Conditions for Work Effectiveness (CWEQ). A follow-up survey will be sent to both groups after the COVID-19 crisis to assess their vulnerability to develop post-trauma stress disorder (PTSD) using a PDS-5 survey.
The objectives of this study are to analyze the best device for intubation in patients infected by SARS-CoV2 virus during COVID-19 pandemics and to review the optimal methods for airway management in such patients for elective surgery and in the Critical Care environment. Also, the safest methods for airway management in thoracic surgery will be analyzed. This study has a descriptive design with no hypothesis contrast, and it will explore the current picture in airway management in Spain. It is a multicentric international study, for all the centers where intubations of tracheostomies have been performed in patients diagnosed with SARS-CoV2 with positive PCR, either in the Critical Care setting or the operating room. A survey will be distributed among professionals who have been involved in airway management in COVID-19 patients in the following specialties: Anesthesiology and Critical Care Medicine, Emergency Medicine, Prehospital Medicine, Cardiology and Pulmonology. The study started on april 2020 after receiving approval from the Ethics Committee (General University Hospital of Valencia) COVID-19 infection causes respiratory failure needing ventilatory support, which required endotracheal intubation or tracheostomy. This situation poses a significant risk of transmission due to its usual urgent nature, and it often happens in the context of respiratory claudication. For this reason, studying the safest and useful methods for airway management in this kind of patients, using data based on the clinical experience, may be of great interest in the future. Statistical analysis will be performed using Statistical Software R, . Technical characteristics will be described using frequencies and percentages for categorical variables, and means and standard deviations or medians and interquartile ranges for continuous variables, depending on normality tests. Base characteristics, center and years of experience will be compared. A sample size calculation is not necessary, since it is an explorative and voluntary study, trying to establish which are the regular routines in airway management in COVID-19 patients in Spain and Latin America.
Description: Preferred device for intubation in COVID-19 patients infected by SARS-CoV2
Measure: Preferred device Time: During COVID-19 pandemics in each country, since the release of the survey until its closure, approximately 4 monthsTo understand and analyse the global impact of COVID-19 on outpatient services, inpatient care, elective surgery, and perioperative colorectal cancer care, a DElayed COloRectal cancer surgery (DECOR-19) survey was conducted in collaboration with numerous international colorectal societies with the objective of obtaining several learning points from the impact of the COVID-19 outbreak on our colorectal cancer patients which will assist us in the ongoing management of our colorectal cancer patients and to provide us safe oncological pathways for future outbreaks.
Description: Respondents' and hospitals' demographics include: gender, country of origin, type of hospital (i.e. academic or not), type of unit (general surgery vs. colorectal), no. hospital beds, no. yearly surgeries for colon and rectal cancer, hospital preparedness to the emergency (i.e. fully or partially dedicated or not involved in COVID-19 care), readily availability of external facilities for colorectal cancer surgery, cancer care coordinator, personal protective equipment, status of elective surgery, no. elective colorectal cancer patients needing urgent surgery, any change in the original management plan, no. colorectal cancer patients refusing surgery or being COVID-19 + on surgery or becoming COVID-19 + post-operatively, no. staff members quarantined or relocated in COVID-19 units, MDT meeting suspension, any delay in endoscopy, radiology, oncology, surgery, histopathology.
Measure: Predictive power of respondents' and hospitals' demographics on delaying colorectal cancer care across 6 geographical regions Time: 20 daysThe aim of this study is to evaluate the knowledge level of healthcare professionals such as physicians, nurses, physiotherapists and nutritionist about published COVID-19 guidelines. The listed healthcare workers are take part in the primary treatment of the Corona virus infected patients in hospitals. Therefore the knowledge of the world wide spreading Corona Virus and its effects for the human being is should be known for the effective treatment and for raising public awareness.
Description: The purpose of the knowledge, attitude and practise questionnaire; to measure the knowledge, attitude and skill levels of healthcare professionals against the COVID-19 virus. In addition, this study will demonstrate the change in the knowledge, attitudes and practise of different healthcare professionals regarding COVID-19. This questionnaire was developed by Istinye University Faculty of Health Science, Physiotherapy and Rehabilitation Department.
Measure: Questionnaire for the Evaluation of Knowledge, Attitude and Practise Levels of Healthcare Professionals for COVID-19 Time: 4 weeksDescription: This questionnaire has been used to evaluate the knowledge and guidance of healthcare professionals about which best approaches can be used to support patients who have had COVID-19 diagnosis and recovered. This questionnaire was developed by Istinye University Faculty of Health Science, Physiotherapy and Rehabilitation Department.
Measure: Support Approach Survey for Patients in Recovery Stage after COVID-19 Diagnosis Time: 4 weeksDescription: The emergence of the COVID-19 and its consequences has led to fears, worries, and anxiety among individuals and health professionals worldwide. The Fear of COVID-19 Scale (FCV-19S) was developed to complement the clinical efforts in preventing the spread and treating of COVID-19 cases. We are going to evaluate the fear of COVID-19 in health professionals.
Measure: Fear of COVID-19 Scale Time: 4 weeksThe current study is aimed to determine the procedures applied in the dysphagia clinics during the COVID-19 pandemic period. A questionnaire consisting of 30 questions will be implemented. Each participant will be asked to answer the questions.
Description: An online survey will be designed to understand the current clinical conditions and current practice regarding dysphagia management during the pandemic period/normalization period
Measure: Online survey Time: 3 monthsThe COVID-19 (coronavirus) pandemic has had a huge impact on healthcare resources and staff in the UK. Understanding the key risk factors associated with infection amongst healthcare workers is essential for future pandemic response plans. Currently there are scarce data relating to the infection rates and associated factors amongst healthcare workers in the United Kingdom (UK). Studies of infection rates in healthcare workers have largely relied on the real-time reverse transcriptase-polymerase chain reaction (RT-PCR) test to date and it appears that Healthcare workers are twice as likely to succumb to Coronavirus infection, when compared to the general population and those from Black and minority ethnic (BAME) backgrounds appear to be particularly at risk. Currently there is no evidence that the presence of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) antibodies provides seasonal or long term immunity to future infection. Therefore, this study aims to understand the current level of SARS-CoV-2 antibody positivity and try to determine the likely risk to healthcare workers in the UK to COVID-19 infection. This study hopes to find out whether certain individual characteristics will have an impact on likelihood of infection susceptibility and antibody response and determine the impact of the presence of antibodies on the likelihood of future clinical infection over a 12 month period. The study involves an initial online survey and linkage to the recent antibody test, then a further online survey in 6 and 12 months' time. The data obtained will be linked to data that the Human Resources Department (HR) holds. Participants also have the option to partake in another antibody test at 6 and 12 months' time and linked to the data collected.
Description: evidence of SARS-CoV-2 antibodies
Measure: The number of employees tested who have evidence of SARS-CoV-2 antibodies Time: 12 monthsDescription: Survey to establish Type of healthcare role Ethnicity Age Index of multiple deprivation Previous RT-PCR test status Previous clinical COVID infection Previous period of self isolation Level of COVID-19 related anxiety Presence of one or more high risk factors for COVID 19 Presence or absence of self-reported COVID 19 symptoms
Measure: Factors associated with a positive test Time: 12 monthsDescription: Infection compared to antibody presence
Measure: Likelihood of clinically relevant (causing illness) infection with SARS-CoV-2 in subjects with both positive and negative SARS-CoV-2 antibody tests Time: 12 monthsThe objectives of this study are to report the response strategy to prevent COVID-19 spread implemented at a Korean medicine hospital, and the satisfaction survey results regarding its preventive measures.
Description: Multiple choice question on satisfactory service regarding hospital response to COVID-19, if any
Measure: Satisfactory service regarding hospital response to COVID-19 Time: Baseline (time of current visit)Description: Likert scale question on level of feelings of apprehension before hospital visits due to COVID-19
Measure: Feelings of apprehension regarding hospital visits Time: Baseline (time of current visit)Description: Likert scale question on level of maintenance of wearing of facial masks and hand hygiene in medical staff
Measure: Medical staff wearing of facial masks and hand hygiene Time: Baseline (time of current visit)Description: Likert scale question on level of cleanliness and sterilization of hospital facilities with regard to COVID-19 spread prevention
Measure: Cleanliness and sterilization of hospital facilities Time: Baseline (time of current visit)Description: Likert scale question on level of convenience and accessibility of hand sanitizers
Measure: Convenience and accessibility of hand sanitizers Time: Baseline (time of current visit)Description: Likert scale question on level of helpfulness and readability of posters and stand-up banners with COVID-19 information in the hospital
Measure: Helpfulness and readability of posters and stand-up banners Time: Baseline (time of current visit)Description: Likert scale question on level of satisfaction with hospital safety measures for COVID-19
Measure: Satisfaction with hospital safety measures for COVID-19 Time: Baseline (time of current visit)Description: Likert scale question on level of recommendation of this hospital to friends and family concerned with visiting hospitals due to COVID-19
Measure: Recommendation of hospital to friends and family Time: Baseline (time of current visit)In late 2019, a novel coronavirus, SARS-CoV-2, was identified as the causative agent of a cluster of pneumonia cases (COVID-19) in Wuhan, China. Clinical symptoms of COVID-19 may be mild or severe. The location where a person will self-isolate will be determined by their healthcare provider and their health authority. When determining the location, several factors to determine the suitability of the home setting are described as the case should stay in a room of their own so that they can be isolated from other household members. The rapid increase and evolution of modern mobile applications for communication and messaging for personal purposes have proved great benefit in healthcare management
The COVID-19 pandemic is having a profound impact on the world. As of May 18, 2020, there were 4,889,287 confirmed cases and 322,683 deaths globally. The healthcare system is wrestling with a virus that threatens to overwhelm hospital capacity, while simultaneously confronting an unprecedented reduction in elective and non-essential care. A survey by the American Cancer Society showed that 50% of cancer patients and survivors reported some impact to their healthcare due to the COVID-19 epidemic. A recent survey was conducted by Forbes et al to evaluate the changes in GI and endoscopy practices in North America. However, the impact of this epidemic on Pulmonology units ( bronchoscopy, thoracoscopy, ultrsonography and sleep lab) globally has not been studied.
Description: number of patients and procedures before and after pandemic
Measure: global impact of COVID-19 on baseline patients number Time: 6 monthsDescription: use of PPE
Measure: measure the changes in practice in each unit Time: 6 monthsDescription: SARS-CoC-2 infection
Measure: frequency of SARS-CoV-2 infection in healthcare workers Time: 6 monthsAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports