Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
Name (Synonyms) | Correlation | |
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drug4249 | Vitamin C Wiki | 0.27 |
drug1775 | Hydroxychloroquine Wiki | 0.10 |
Name (Synonyms) | Correlation | |
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D045169 | Severe Acute Respiratory Syndrome NIH | 0.04 |
D018352 | Coronavirus Infections NIH | 0.04 |
Name (Synonyms) | Correlation |
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Navigate: Correlations HPO
There is one clinical trial.
Coronavirus Disease 2019 (COVID-19) is spreading worldwide and has become a public health emergency of major international concern. Currently, no specific drugs or vaccines are available. For severe cases, it was found that aberrant pathogenic T cells and inflammatory monocytes are rapidly activated and then producing a large number of cytokines and inducing an inflammatory storm. Mesenchymal stem cells (MSCs) have been shown to possess a comprehensive powerful immunomodulatory function. This study aims to investigate the safety and efficacy of intravenous infusion of mesenchymal stem cells in severe patients with COVID-19.
Description: Assessment of Overall survival at 30 days post intervention
Measure: Overall survival Time: 60 daysDescription: To assess the anti-inflammatory effect of the proposed treatment with assessment of the levels of C-reactive protein (mg/dL)
Measure: Changes on inflammatory C-reactive protein Time: 60 daysDescription: days of the patients in hospital
Measure: Hospital stay Time: 60 daysDescription: Evaluation of functional respiratory changes: PaO2 / FiO2 ratio
Measure: Oxygenation index (PaO2/FiO2) Time: 60 daysDescription: Improvement in Liao's score (2020)
Measure: Improvement in Liao's score (2020) Time: 60 daysDescription: Computed tomography Chest assesment will be done to assess improvement in radiological findings of COVID-19
Measure: Radiological improvement Time: 60 daysDescription: PCR testing to check PCR negativity
Measure: Time of COVID19 PCR negativity Time: 28 daysAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports