Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug3751 | Standard smoking cessation therapy for TUD plus Chess-based cognitive treatment Wiki | 1.00 |
| drug3756 | Standard therapy for AUD plus Chess-based cognitive treatment Wiki | 1.00 |
| drug3755 | Standard therapy for AUD Wiki | 1.00 |
| Name (Synonyms) | Correlation |
|---|
Navigate: Correlations HPO
There is one clinical trial.
Neurobiological and neuropsychological approaches to investigate the potential mechanism of action of chess as an add-on therapy (chess based - cognitive remediation treatment, CB-CRT) to reduce cognitive deficits in individuals with alcohol use disorder (AUD).
Description: fMRI cue-reactivity task (Vollstädt-Klein et al. 2010)
Measure: change in neural cue-reactivity Time: 2 time points: before and after 6 weeks chess-based cognitive trainingDescription: fMRI sequential reinforcement-based task (Huys et al. 2012)
Measure: change in sequential reinforcement-based neural mechanisms Time: 2 time points: before and after 6 weeks chess-based cognitive trainingDescription: fMRI stop-signal task (Whelan et al. 2012)
Measure: change in neural correlates of inhibition Time: 2 time points: before and after 6 weeks chess-based cognitive trainingDescription: self-report
Measure: substance use (alcohol consumption and tabacco use) Time: 3 months follow-up after the end of treatmentDescription: fMRI spatial working memory task (Vollstädt-Klein et al. 2010)
Measure: change in neural working memory processes Time: 2 time points: before and after 6 weeks chess-based cognitive trainingDescription: working memory capacity measured by letter-number sequencing task of the [Wechsler Memory Scale (Kent 2013)]; raw values will be transformed to IQ-like scales (mean 100, SD 15); the higher the value, the higher the working memory capacity
Measure: Change in working memory capacity Time: 3 time points: before and after 6 weeks SCP plus after 3 monthsDescription: One Touch Stockings of Cambridge task from the Cambridge Automated Neuropsychological Test Automated Battery (Robbins et al. 1994)
Measure: Change in planning ability Time: 3 time points: before and after 6 weeks SCP plus after 3 monthsDescription: Internal-External Set Shifting task from the Cambridge Automated Neuropsychological Test Automated Battery (Robbins et al. 1994)
Measure: Change in cognitive flexibility Time: 3 time points: before and after 6 weeks SCP plus after 3 monthsDescription: impulsivity measured with BIS scale [Barratt impulsiveness scale (Patton et al. 1995)];range 15-60; total score will be used; high values represent high impulsivity
Measure: Change in impulsivity Time: 3 time points: before and after 6 weeks SCP plus after 3 monthsDescription: [Iowa Gambling Task (Bechara et al. 1994)]
Measure: Change in decision-making Time: 3 time points: before and after 6 weeks SCP plus after 3 monthsDescription: [Reversal learning task (Vanes et al. 2014)]
Measure: Change in mental flexibility Time: 3 time points: before and after 6 weeks SCP plus after 3 monthsDescription: [d2 Test of Attention (Brickenkamp 2002)].
Measure: Change in attentional capacity Time: 3 time points: before and after 6 weeks SCP plus after 3 monthsDescription: [measured with fMRI]
Measure: change in functional connectivity within the salience network (SN) and executive control network (ECN) Time: 2 time points: before and after 6 weeks therapy and chess-based cognitive trainingAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports