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| Name (Synonyms) | Correlation | |
|---|---|---|
| drug246 | Alcohol brief intervention Wiki | 1.00 |
| drug3308 | Regular messages through Instant Messaging (IM) Wiki | 1.00 |
| drug27 | 12-page health warning leaflet Wiki | 1.00 |
| Name (Synonyms) | Correlation |
|---|
Navigate: Correlations HPO
There is one clinical trial.
This study aims to assess the effect of personalized support using instant messaging application on alcohol drinking reduction in university students proactively recruited from universities in Hong Kong.
Description: Assessed by unit in gram and compare the alcohol consumption between intervention and control group at 6-month after baseline.
Measure: Amount of alcohol consumption per week (gram/week) at 6-month follow-up Time: 6-month after baselineDescription: To estimate large, moderate and null (same as the control) treatment effects and check whether ITT, AP and PP analysis estimates are biased compared with CACE estimates (alcohol consumption per week at 6-month follow-up)
Measure: Compare the primary outcome using intention-to-treat (ITT), per-protocol (PP) and as-treated (AP) analysis with Compliance Average Causal Effect (CACE) analysis Time: 6-month after baselineDescription: Assessed by unit in gram and compare the alcohol consumption between intervention and control group at 12-month after baseline.
Measure: Amount of alcohol consumption per week (gram/week) at 12-month follow-up Time: 12-month after baselineDescription: Assessed by Alcohol Use Disorders Identification Test (ranged 0-40 with higher score indicating problematic alcohol use) and compare the AUDIT between intervention and control group at 6-month after baseline.
Measure: AUDIT scores at 6-month follow-up Time: 6-month after baselineDescription: Assessed by Alcohol Use Disorders Identification Test (ranged 0-40 with higher score indicating problematic alcohol use) and compare the AUDIT between intervention and control group at 12-month after baseline.
Measure: AUDIT scores at 12-month follow-up Time: 12-month after baselineDescription: Assessed by either increase or decrease in standard drinks number and compared between intervention and control group at 6-month
Measure: Number of standard drinks (10g of alcohol) per week at 6-month follow-up Time: 6-month after baselineDescription: Assessed by either increase or decrease in standard drinks number and compared between intervention and control group at 12-month
Measure: Number of standard drinks (10g of alcohol) per week at 12-month follow-up Time: 12-month after baselineDescription: Defined by 5 standard drink [male] or 4 standard drink [female] in one occasion for binge drinking and compare the episode of binge drinking between intervention group and control at baseline and 6-month follow-up questionnaires
Measure: Episode of binge drinking in the past 30-day at 6-month follow up Time: at 6-month after baselineDescription: Defined by 5 standard drink [male] or 4 standard drink [female] in one occasion for binge drinking and compare the episode of binge drinking between intervention group and control at baseline and 12-month follow-up questionnaires
Measure: Episode of binge drinking in the past 30-day at 12-month follow up Time: at 12-month after baselineDescription: Defined by 15 standard drink [male] or 8 standard drink[female] in a week for heavy drinking and compare the episode of heavy drinking between intervention group and control at baseline and 6-month follow-up questionnaires
Measure: Episode of heavy drinking in the past 30-day at 6-month follow up Time: at 6 -month after baselineDescription: Defined by 15 standard drink [male] or 8 standard drink [female] in a week for heavy drinking and compare the episode of heavy drinking between intervention group and control at baseline and 12-month follow-up questionnaires
Measure: Episode of heavy drinking in the past 30-day at 12-month follow up Time: at 12-month after baselineDescription: Compare the number of planned drinking (yes or no) between intervention group and control group at baseline and 6-month follow-up questionnaires
Measure: Planned drinking measured in the coming 30-day at 6-month follow up Time: at 6-month after baselineDescription: Compare the number of planned drinking (yes or no) between intervention group and control group at baseline and 12-month follow-up questionnaires
Measure: Planned drinking measured in the coming 30-day at 12-month follow up Time: at 12-month after baselineDescription: The four items in this scale addressed the number of times the student had been 'late to class', 'missed class', was 'unable to concentrate' and 'failed to complete assignment' (score range 0-16). The responses included 'not at all', 'once', 'twice', 'three times' and 'four times or more'. The score will be compared between intervention group and control group at baseline and 6-month follow-up questionnaires
Measure: Academic Role Expectation and Alcohol Scale at 6-month follow-up Time: at 6-month after baselineDescription: The four items in this scale addressed the number of times the student had been 'late to class', 'missed class', was 'unable to concentrate' and 'failed to complete assignment' (score range 0-16). The responses included 'not at all', 'once', 'twice', 'three times' and 'four times or more'. The score will be compared between intervention group and control group at baseline and 12-month follow-up questionnaires
Measure: Academic Role Expectation and Alcohol Scale at 12-month follow-up Time: at 12-month after baselineDescription: The 14-item measure of alcohol-related personal, social, sexual, and legal problems (eg, being physically aggressive toward someone while under the influence of alcohol).The score will be compared between intervention group and control group at baseline and 6-month follow-up questionnaires
Measure: Alcohol Problems Scale at 6-month follow-up Time: at 6-month after baselineDescription: The 14-item measure of alcohol-related personal, social, sexual, and legal problems (eg, being physically aggressive toward someone while under the influence of alcohol).The score will be compared between intervention group and control group at baseline and 12-month follow-up questionnaires
Measure: Alcohol Problems Scale at 12-month follow-up Time: at 12- month after baselineDescription: Mediation analysis of 6-month factors (knowledge of alcohol drinking, perception of alcohol drinking, intention to quit drinking, mental health) on weekly amount of alcohol consumption at 12-month
Measure: Mediation analysis of variables at 6-month on weekly amount of alcohol consumption at 12-month Time: at 12- month after baselineDescription: Subgroup analysis to check whether the intervention is more effective with participants with intention to quit/reduce drinking on outcomes
Measure: Subgroup analysis of baseline intention to quit/reduce drinking Time: at 12- month after baselineDescription: The conversations between the participants and the nurse will be analyzed and categorized into different sub-type of BCT taxonomy
Measure: Content analysis of IM Apps conversation using alcohol BCT taxonomy Time: at 12- month after baselineDescription: Total score is determined by adding together the scores of each of the 4 items. Scores are rated as normal (0-2), mild (3-5), moderate (6-8), and severe (9-12). Total score ≥3 for first 2 questions suggests anxiety. Total score ≥3 for last 2 questions suggests depression. The score will be compared between intervention group and control group at baseline and 6-month follow-up questionnaires
Measure: Patient Health Questionnaire 4-item (PHQ-4) at 6-month Time: at 6-month after baselineDescription: Total score is determined by adding together the scores of each of the 4 items. Scores are rated as normal (0-2), mild (3-5), moderate (6-8), and severe (9-12). Total score ≥3 for first 2 questions suggests anxiety. Total score ≥3 for last 2 questions suggests depression. The score will be compared between intervention group and control group at baseline and 12-month follow-up questionnaires
Measure: Patient Health Questionnaire 4-item (PHQ-4) at 12-month Time: at 12-month after baselineDescription: Subjects' responses are measured on a five-point scale (0 = never, 1 = almost never, 2 =sometimes, 3 = fairly often, 4 = very often). Scoring: PSS-4 scores are obtained by summing across all four items. Scoring items 2 and 3 require reverse coding. This involves assigning the opposite score. For example, a score of 0=4, 1=3, 2=2, 3=1, and 4=0. The higher the score, the more perceived stress. The score will be compared between intervention group and control group at baseline and 6-month follow-up questionnaires
Measure: Perceived Stress Scale 4-item (PSS-4) at 6-month Time: at 6-month after baselineDescription: Subjects' responses are measured on a five-point scale (0 = never, 1 = almost never, 2 =sometimes, 3 = fairly often, 4 = very often). Scoring: PSS-4 scores are obtained by summing across all four items. Scoring items 2 and 3 require reverse coding. This involves assigning the opposite score. For example, a score of 0=4, 1=3, 2=2, 3=1, and 4=0. The higher the score, the more perceived stress. The score will be compared between intervention group and control group at baseline and 12-month follow-up questionnaires
Measure: Perceived Stress Scale 4-item (PSS-4) at 12-month Time: at 12-month after baselineDescription: Score ranges from 0 to 10 with higher score indicates a higher level of usefulness of our intervention.
Measure: Perceived usefulness of IM app intervention at 12-month Time: at 12-month after baselineDescription: Ask for intention to use (yes/no) IM app intervention to reduce/quit drinking at 12-month
Measure: Intention to continue using IM app intervention at 12-month Time: at 12-month after baselineDescription: Perceived difficulty, confidence and importance of quitting/reducing to drink will be asked. Score ranges from 0 to 10 with higher score indicates a high level. The score will be compared between intervention group and control group at baseline and 6-month follow-up questionnaires
Measure: Self-efficacy to reduce/quit drinking at 6-month Time: at 6-month after baselineDescription: Perceived difficulty, confidence and importance of quitting/reducing to drink will be asked. Score ranges from 0 to 10 with higher score indicates a high level. The score will be compared between intervention group and control group at baseline and 12-month follow-up questionnaires
Measure: Self-efficacy to reduce/quit drinking at 12-month Time: at 12-month after baselineDescription: Assessed by stop drinking, increase (+50%), slight increase, decrease (-50%), slight decrease or no change of drinking after the start of pandemic
Measure: Covid-19 related drinking behavioral changes at baseline Time: at baselineDescription: Assessed by stop drinking, increase (+50%), slight increase, decrease (-50%), slight decrease or no change of drinking after the start of pandemic. The changes will be compared between the intervention group and control group at 6-month
Measure: Covid-19 related drinking behavioral changes at 6-month Time: at 6-monthDescription: Assessed by stop drinking, increase (+50%), slight increase, decrease (-50%), slight decrease or no change of drinking after the start of pandemic. The changes will be compared between the intervention group and control group at 12-month
Measure: Covid-19 related drinking behavioral changes at 12-month Time: at 12-monthAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
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