Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug3091 | Probiotic and LC-PUFA Wiki | 1.00 |
| drug2916 | Placebo Wiki | 0.04 |
| Name (Synonyms) | Correlation | |
|---|---|---|
| D009461 | Neurologic Manifestations NIH | 0.41 |
| D018352 | Coronavirus Infections NIH | 0.04 |
| Name (Synonyms) | Correlation |
|---|
Navigate: Correlations HPO
There is one clinical trial.
Probiotics is suggested to play several roles in promoting health, including alleviating disease symptoms, protection against atopic disease, and modulating the immune system by improving the beneficial gut microbiota colonization. The discovery of the gut microbiota-brain axis suggested that there is a reciprocal influence between the brain and the gut through a constant communication. This bi-directional axis enables signals to be transferred from brain to influence sensory, motor, and secretory modalities of the GI tract, also permits signal from the gut to influence brain function. The establishment of intestinal microbiota during early neurodevelopmental period suggests the colonization and maturation of gut microbiota may influence brain development. Several studies have shown there is an association between shifts in the gut microbiota composition in children with neurodevelopmental disorders. This study aims to investigate how maternal probiotic + LC-PUFA supported with government program supplements, healthy eating, and psychosocial stimulation could affect fetal brain development and later child brain functions and cognitive development. Intervention would be delivered to pregnant women for 9 months, starting at the end of second trimester of gestational period.
Description: measured in parenchymal and cortical regions
Measure: Total brain volume Time: 1 yearDescription: Myelination index
Measure: Fetal brain development Time: 1 yearDescription: Looking time (s) as a response to stimuli differentiation at 4 months of age
Measure: Child cognitive and brain function at 4 months of age Time: 1 yearDescription: BSID-III
Measure: Child cognitive at 6 months of age Time: 1 monthDescription: BERA
Measure: Brain function at 6 months of age Time: 1 monthDescription: Edinburgh Postnatal Depression Scale (EPDS)
Measure: Mother depression scale Time: 1 yearDescription: Visual acuity
Measure: Cognitive development and brain function at 4-months of age Time: 1 yearDescription: Baby weighing scale
Measure: Birth weight Time: 1 monthDescription: Change in weight-for-age z-score
Measure: Child's Growth Time: 6 monthsDescription: Change in Length-for-age z-score
Measure: Child's linear growth Time: 6 monthsDescription: Change in Head-circumference-for-age
Measure: Head circumference Time: 6 monthsDescription: Change in weight-for-length z score
Measure: Child nutritional status Time: 6 monthsDescription: Maternal involvement using HOME inventory questionnaires
Measure: Quality of interaction with parents Time: 1 yearDescription: Zinc, iron, folate blood level
Measure: Maternal micronutrient status Time: 1 yearDescription: Blood glucose
Measure: Gestational diabetes Time: 1 yearDescription: Diagnosed by doctor
Measure: Pre-eclampsia Time: 1 yearDescription: Gestational age
Measure: Preterm birth Time: 1 yearDescription: actual dietary intake, dietary pattern and quality
Measure: Mother's dietary quality Time: 1 yearDescription: Microbiota composition by S16rRNA analysis
Measure: Fecal microbiota composition Time: 1 yearAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports