Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
| Name (Synonyms) | Correlation |
|---|
| Name (Synonyms) | Correlation | |
|---|---|---|
| D007239 | Infection NIH | 0.05 |
| D045169 | Severe Acute Respiratory Syndrome NIH | 0.04 |
| D018352 | Coronavirus Infections NIH | 0.04 |
| Name (Synonyms) | Correlation |
|---|
Navigate: Correlations HPO
There is one clinical trial.
Personal protective equipment (PPE) is vital to ensuring staff safety during the COVID-19 pandemic. Properly designed, formal PPE (fPPE) is in increasingly short supply, and a series of improvised PPE (iPPE) designs have been widely circulated on the internet, particularly on social media. Groups have started to publicise these devices through websites and the lay press. Some are even using crowd-funding to finance the purchase of these systems with the intention of supplying NHS workers in place of approved systems. It is not clear what degree of testing these systems have undergone. The investigators are already planning trials formally investigating the quality of seal offered by these improvised systems. Currently the team are investigating a designed based on a modified snorkel mask (STRIPE-1). In the current study the investigators wish to extend this investigation to consider the atmosphere within the mask. This is an important question, as modifications to the snorkel design have changed the way gases mix within the system. This might increase the risk that the user will rebreathe expired gases, which will dilute the amount of oxygen available to them, and increase the carbon dioxide levels to which they are exposed. At extreme deviations, these might pose a potential health hazard over and above the risks posed by COVID-19 exposure via a poor mask seal. This study will therefore recruit a convenience sample of 10, and request they wear two masks sequentially. These masks will comprise: a formally designed and tested commercial FFP3 mask, and one design of improvised PPE, based on the snorkel design available on the internet. Each mask will be worn for a total of 40 minutes. In the first 20 minutes measurements will be taken with the user at rest. In the second 20 minutes measurements will be taken while the user undertakes light exercise.
Description: 5-minute measurement of oxygen concentration in inspired and expired gases
Measure: Oxygen concentration while wearing purpose-designed mask Time: 40 minutes starting from intervention (donning of mask)Description: 5-minute measurement of oxygen concentration in inspired and expired gases
Measure: Oxygen concentration while wearing improvised snorkel-based mask Time: 40 minutes starting from intervention (donning of mask)Description: 5 minute measurement of carbon dioxide concentration in inspired and expired gases
Measure: Carbon dioxide concentration while wearing purpose-designed mask Time: 40 minutes starting from intervention (donning of mask)Description: 5 minute measurement of carbon dioxide concentration in inspired and expired gases
Measure: Carbon dioxide concentration while wearing improvised snorkel-based mask Time: 40 minutes starting from intervention (donning of mask)Description: 5 minute measurement of heart rate
Measure: Heart rate while wearing purpose-designed mask Time: 40 minutes starting from intervention (donning of mask)Description: 5 minute measurement of heart rate
Measure: Heart rate while wearing improvised snorkel-based mask Time: 40 minutes starting from intervention (donning of mask)Description: 5 minute measurement of respiratory rate
Measure: Respiratory rate while wearing purpose-designed mask Time: 40 minutes starting from intervention (donning of mask)Description: 5 minute measurement of respiratory rate
Measure: Respiratory rate while wearing improvised snorkel-based mask Time: 40 minutes starting from intervention (donning of mask)Description: 5 minute measurement of oxygen saturation
Measure: Oxygen saturation while wearing purpose-designed mask Time: 40 minutes starting from intervention (donning of mask)Description: 5 minute measurement of oxygen saturation
Measure: Oxygen saturation while wearing improvised snorkel-based mask Time: 40 minutes starting from intervention (donning of mask)Alphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports