Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug4556 | lopinavir/ritonavir tablets or Arbidol or chloroquine phosphate Wiki | 1.00 |
| drug858 | Carrimycin Wiki | 1.00 |
| drug4389 | basic treatment Wiki | 0.71 |
| Name (Synonyms) | Correlation | |
|---|---|---|
| D003141 | Communicable Diseases NIH | 0.07 |
| D007239 | Infection NIH | 0.05 |
| D018352 | Coronavirus Infections NIH | 0.04 |
| Name (Synonyms) | Correlation |
|---|
Navigate: Correlations HPO
There is one clinical trial.
The aim is to develop a wearable-based ICU (intensive care unit) prediction algorithm for inpatients contracted with SARS-CoV-2. Inpatients with suspicion of COVID-19 or with confirmed SARS-CoV-2 infection will be included. The participants will be equipped with a smartwatch, which gathers physiological data throughout hospitalisation.
Description: Accuracy of the WAVE-model will be assessed using physiological data recorded by the smartwatch (Garmin vivoactive 4) during hospitalization complemented by demographic and health-related patient-information and will be analysed using applied machine learning technology for ICU prediction.
Measure: Diagnostic accuracy of smartwatch data in predicting ICU requirement in COVID-19 contracted inpatients quantified as the area under the receiver operator characteristics curve (AUC ROC > 0.85). Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Accuracy of the model will be assessed using physiological data routinely recorded during hospitalization and will be analysed using applied machine learning technology for ICU prediction.
Measure: Diagnostic accuracy of routine physiological data in predicting ICU requirement in COVID-19 contracted in-patients quantified as the area under the receiver operator characteristics curve (AUC ROC > 0.85). Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Accuracy of the model will be assessed using data on comorbidities, medication treatment during hospitalization and physiological data and will be analysed using casual machine-learning approaches
Measure: Diagnostic accuracy of predicting hospital discharge without ICU admission in COVID-19 contracted in-patients quantified as area under the receiver operator characteristics curve Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Heart rate will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S) and using routine medical monitors.
Measure: Change of heart rate from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Heart rate variability will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)
Measure: Change of heart rate variability from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Skin temperature will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)
Measure: Change of skin temperature from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Blood oxygen saturation will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S) and using routine medical monitors
Measure: Change of blood oxygen saturation from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Respiration rate will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S) and using routine medical monitors
Measure: Change of respiration rate from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Physical activity will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)
Measure: Change of physical activity from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Stress level will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)
Measure: Change of stress level from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Sleep will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)
Measure: Change of sleep pattern from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Steps per day will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)
Measure: Change of steps per day from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Systolic blood pressure will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S) and using routine medical monitors
Measure: Change of systolic blood pressure from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Diastolic blood pressure will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S) and using routine medical monitors
Measure: Change of diastolic blood pressure from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Body temperature will be recorded throughout the hospitalization using a routine medical thermometer
Measure: Change of body temperature from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Oxygen partial pressure (pO2) will be routinely assessed during the hospitalization in arterial or venous blood gas analyses
Measure: Change of oxygen partial pressure (pO2) from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: CO2 partial pressure (pCO2) will be routinely assessed during the hospitalization in arterial or venous blood gas analyses
Measure: Change of CO2 partial pressure (pCO2) from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Blood pH will be routinely assessed during the hospitalization in arterial or venous blood gas analyses
Measure: Change of blood pH from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Bicarbonate will be routinely assessed during the hospitalization in arterial or venous blood gas analyses
Measure: Change of bicarbonate from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Base excess will be routinely assessed during the hospitalization in arterial or venous blood gas analyses
Measure: Change of base excess from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Oxygen flow rate will be routinely assessed during the hospitalization
Measure: Change of oxygen flow rate from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Alphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports