Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
| Name (Synonyms) | Correlation |
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| Name (Synonyms) | Correlation |
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Navigate: Correlations HPO
There is one clinical trial.
This is an observational study, in which people recovering from COVID-19 infection will attend an outpatient clinic for a comprehensive swallowing assessment. The assessment will include a videofluoroscopy, measurement of respiratory-swallow coordination using a digital stethoscope, measures of tongue and cough strength and patient reported measures that will help us to understand the presence and impact of swallowing impairment (dysphagia) in this population.
Description: Frequency of boluses (per consistency) demonstrating airway invasion, defined as Penetration-Aspiration Scale score of 3 and higher (Rosenbek et al., 1996)
Measure: Swallowing safety Time: Videofluoroscopy session (single timepoint only)Description: Frequency of boluses (per consistency) demonstrating pharyngeal residue measured to fill more than 1% of an anatomical reference scalar [%(C2-4)squared] (Steele et al., 2019)
Measure: Swallowing efficiency Time: Videofluoroscopy session (single timepoint only)Description: Frequency of boluses (per consistency) on which the participant displays prolonged time to airway closure (i.e. Laryngeal Vestibule Closure), defined as values falling more than 1 standard deviation above the healthy reference mean (Steele et al., 2019)
Measure: Time-to-Laryngeal-Vestibule-Closure Time: Videofluoroscopy session (single timepoint only)Description: Frequency of boluses (per consistency) on which the participant displays short airway closure (i.e. laryngeal vestibule closure), defined as a duration more than 1 standard deviation below the healthy reference mean (Steele et al., 2019)
Measure: Laryngeal Vestibule Closure duration Time: Videofluoroscopy session (single timepoint only)Description: Frequency of boluses (per consistency) on which the participant displays pharyngeal area above the 75th percentile healthy reference value on the frame of maximum constriction (Steele et al., 2019)
Measure: Pharyngeal Constriction Time: Videofluoroscopy session (single timepoint only)Alphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports