Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
Navigate: Correlations HPO
There is one clinical trial.
Obesity is a major risk factor for mobility problems in older adults and many older adults use a walking aid to help with their mobility. The use of a walking aid changes normal walking patterns and makes walking harder, leading people to have more functional problems. The purpose of this study is to test the effects of 12 months of a multi-modal balance intervention (MMBI) with supervised weight loss compared to MMBI only on fitness, functional performance, balance, and economy of gait. Participants will be one of 120 participants in the VAMHCS. Participation in this study is voluntary. The research will be conducted at the VAMHCS. The entire study will take approximately 4 years to complete. Subjects' participation in the study will last 24 months.
Description: Distance walked during the 6 minute walking test
Measure: Change in 6 minute walk distance Time: baseline, 3 months, 6 months, 12 months, 24 monthsDescription: VO2peak measured during graded exercise treadmill test to volitional fatigue
Measure: Change in VO2peak Time: baseline, 6 months, 12 months, 24 monthsDescription: 6 minute walk with submaximal assessment of oxygen uptake.
Measure: Change in 6 minute walk with VO2 measurement Time: baseline, 3 months, 6 months, 12 months, 24 monthsDescription: DXA scan
Measure: Change in Muscle mass/body composition as assessed by DXA scan Time: baseline, 6 months, 12 months, 24 monthsDescription: LLDFI Questionnaires
Measure: Change in Quality of Life, LLDFI Time: baseline, 3 months, 6 months, 12 months, 24 monthsDescription: Gait biomechanics as assessed by walking mechanics on the GAITmat
Measure: Change in gait biomechanics Time: baseline, 3 months, 6 months, 12 months, 24 monthsDescription: Component scores of the standing balance battery, usual gait speed, and repeated chair stands (which make up the short physical performance battery test); as well as overall short physical performance battery score
Measure: Change in short physical performance battery Time: baseline, 3 months, 6 months, 12 months, 24 monthsDescription: Dynamic test of balance involving change in stepping direction.
Measure: Change in four square step test Time: baseline, 3 months, 6 months, 12 months, 24 monthsDescription: Time to get up from a chair and walk around a cone 8 feet away and sit back down, representing agility.
Measure: Change in 8 foot up and go Time: baseline, 3 months, 6 months, 12 months, 24 monthsDescription: CT scan
Measure: Change in Muscle mass/body composition as assessed by CT scan Time: baseline, 6 months, 12 months, 24 monthsDescription: Self-reported ability to complete activities of daily living and independent activities of daily living.
Measure: Change in ADL/IADL questionnaire Time: baseline, 3 months, 6 months, 12 months, 24 monthsDescription: Self-reported physical activities questionnaire.
Measure: Change in CHAMPS questionnaire Time: baseline, 3 months, 6 months, 12 months, 24 monthsDescription: Questionnaire assessing global cognitive function
Measure: Change in MoCA Time: baseline, 3 months, 6 months, 12 months, 24 monthsAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports