Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug4806 | vitamin d Wiki | 0.71 |
| drug832 | Camostat Mesilate Wiki | 0.25 |
| drug2916 | Placebo Wiki | 0.03 |
| Name (Synonyms) | Correlation | |
|---|---|---|
| D001714 | Bipolar Disorder NIH | 0.50 |
| D003865 | Depressive Disorder, Major NIH | 0.32 |
| D003866 | Depressive Disorder NIH | 0.26 |
| Name (Synonyms) | Correlation | |
|---|---|---|
| HP:0100754 | Mania HPO | 0.50 |
| HP:0000716 | Depressivity HPO | 0.26 |
Navigate: Correlations HPO
There are 2 clinical trials
The current study aims to assess the feasibility, acceptance and clinical outcomes of a practical high-dose aiTBS protocol, including tapering treatments and symptom-based relapse prevention treatments, in patients with unipolar depression previously responsive to ECT and patients needing urgent treatment due to symptom severity during the COVID-19 pandemic.
Description: Less than or equal to 10
Measure: Proportion achieving remission on Hamilton Rating Scale for Depresion 24-it (HRSD-24) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: changes in scores
Measure: Change in HRSD-24 Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: 50% Reduction in score
Measure: Response on HRSD-24 Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: Less than or equal to 4
Measure: Remission on Patient Health Questionnaire (PHQ-9) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: 50% Reduction in score
Measure: Response on PHQ-9 Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: changes in scores
Measure: Change in PHQ-9 Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: Less than or equal to 4
Measure: Remission on General Anxiety Disorder 7 item (GAD-7) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: 50% Reduction in score
Measure: Response on GAD-7 Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: changes in scores
Measure: Change in GAD-7 Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: Less than or equal to 12
Measure: Remission on Beck Depression Inventory (BDI-II) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: 50% Reduction in Score
Measure: Response on BDI-II Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: changes in scores
Measure: Change on BDI-II Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: Score of 0
Measure: Remission on Beck Scale for Suicidal Ideation (SSI) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: changes in scores
Measure: Change on SSI Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: changes in scores
Measure: Change in WHO Disability Assessment Schedule (WHODAS) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: Includes number of treatment days needed and number going on to receive ECT
Measure: Proportion of Patients Maintaining Response During Relapse Prevention Time: 24 weeks (Tapering and Relapse prevention phase)The current study aims to assess the feasibility, acceptance and clinical outcomes of a practical high-dose LFR protocol, including tapering treatments and symptom-based relapse prevention treatments, in patients with bipolar depression previously responsive to ECT and patients needing urgent treatment due to symptom severity during the COVID-19 pandemic.
Description: Less than or equal to 10 This scale is used to quantify the severity of symptoms of depression Scale range: 0-76 (total score) Lower scores indicate lower severity of depressive symptoms (i.e., better outcome) Higher scores indicate higher severity of depressive symptoms (i.e., worse outcome)
Measure: Proportion achieving remission on Hamilton Rating Scale for Depresion 24-it (HRSD-24) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: changes in scores This scale is used to quantify the severity of symptoms of depression Scale range: 0-76 (total score) Lower scores indicate lower severity of depressive symptoms (i.e., better outcome) Higher scores indicate higher severity of depressive symptoms (i.e., worse outcome)
Measure: Change in Hamilton Rating Scale for Depresion 24-it (HRSD-24) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: 50% Reduction in score This scale is used to quantify the severity of symptoms of depression Scale range: 0-76 (total score) Lower scores indicate lower severity of depressive symptoms (i.e., better outcome) Higher scores indicate higher severity of depressive symptoms (i.e., worse outcome)
Measure: Response on Hamilton Rating Scale for Depresion 24-it (HRSD-24) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: changes in scores This scale is used to quantify the severity of symptoms of mania Scale range: 0-60 (total score) Lower scores indicate lower severity of manic symptoms (i.e., better outcome) Higher scores indicate higher severity of manic symptoms (i.e., worse outcome)
Measure: Change in Young Mania Rating Scale (YMRS) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: Less than or equal to 4 This scale is used to quantify the severity of symptoms of depression Scale range: 0-27 (total score) Lower scores indicate lower severity of depressive symptoms (i.e., better outcome) Higher scores indicate higher severity of depressive symptoms (i.e., worse outcome)
Measure: Remission on Patient Health Questionnaire (PHQ-9) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: 50% Reduction in score This scale is used to quantify the severity of symptoms of depression Scale range: 0-27 (total score) Lower scores indicate lower severity of depressive symptoms (i.e., better outcome) Higher scores indicate higher severity of depressive symptoms (i.e., worse outcome)
Measure: Response on Patient Health Questionnaire (PHQ-9) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: changes in scores This scale is used to quantify the severity of symptoms of depression Scale range: 0-27 (total score) Lower scores indicate lower severity of depressive symptoms (i.e., better outcome) Higher scores indicate higher severity of depressive symptoms (i.e., worse outcome)
Measure: Change in Patient Health Questionnaire (PHQ-9) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: Less than or equal to 4 This scale is used to quantify the severity of symptoms of anxiety Scale range: 0-21 (total score) Lower scores indicate lower severity of anxiety symptoms (i.e., better outcome) Higher scores indicate higher severity of anxiety symptoms (i.e., worse outcome)
Measure: Remission on General Anxiety Disorder 7 item (GAD-7) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: 50% Reduction in score This scale is used to quantify the severity of symptoms of anxiety Scale range: 0-21 (total score) Lower scores indicate lower severity of anxiety symptoms (i.e., better outcome) Higher scores indicate higher severity of anxiety symptoms (i.e., worse outcome)
Measure: Response on General Anxiety Disorder 7 item (GAD-7) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: changes in scores This scale is used to quantify the severity of symptoms of anxiety Scale range: 0-21 (total score) Lower scores indicate lower severity of anxiety symptoms (i.e., better outcome) Higher scores indicate higher severity of anxiety symptoms (i.e., worse outcome)
Measure: Change in General Anxiety Disorder 7 item (GAD-7) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: Less than or equal to 12 This scale is used to quantify the severity of symptoms of depression Scale range: 0-63 (total score) Lower scores indicate lower severity of depressive symptoms (i.e., better outcome) Higher scores indicate higher severity of depressive symptoms (i.e., worse outcome)
Measure: Remission on Beck Depression Inventory (BDI-II) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: 50% Reduction in Score This scale is used to quantify the severity of symptoms of depression Scale range: 0-63 (total score) Lower scores indicate lower severity of depressive symptoms (i.e., better outcome) Higher scores indicate higher severity of depressive symptoms (i.e., worse outcome)
Measure: Response on Beck Depression Inventory (BDI-II) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: changes in scores This scale is used to quantify the severity of symptoms of depression Scale range: 0-63 (total score) Lower scores indicate lower severity of depressive symptoms (i.e., better outcome) Higher scores indicate higher severity of depressive symptoms (i.e., worse outcome)
Measure: Change on Beck Depression Inventory (BDI-II) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: Score of 0 This scale is used to assess the presence or absence of suicidal ideation and the degree of severity of suicidal ideas Scale range: 0 - 38 (total score) Lower scores indicate lower severity of suicidal ideation (i.e., better outcome) Higher scores indicate higher severity of suicidal ideation (i.e., worse outcome)
Measure: Remission on Beck Scale for Suicidal Ideation (SSI) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: changes in scores This scale is used to assess the presence or absence of suicidal ideation and the degree of severity of suicidal ideas Scale range: 0 - 38 (total score) Lower scores indicate lower severity of suicidal ideation (i.e., better outcome) Higher scores indicate higher severity of suicidal ideation (i.e., worse outcome)
Measure: Change on Beck Scale for Suicidal Ideation (SSI) Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: changes in scores
Measure: Change in WHO Disability Assessment Schedule (WHODAS) Range 0-38 Time: Up to 10 days (From screening/baseline to end of the acute treatment)Description: Includes number of treatment days needed and number going on to receive ECT
Measure: Proportion of Patients Maintaining Response During Relapse Prevention Time: 24 weeks (Tapering and Relapse prevention phase)Alphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports