Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug4705 | retrospective metagenomics on clinical samples collected during hospitalization Wiki | 1.00 |
| drug371 | Assigned Strategies: Enhanced Active Choice Wiki | 1.00 |
| drug915 | Choice of Assignment: Enhanced Active Choice Wiki | 1.00 |
| Name (Synonyms) | Correlation | |
|---|---|---|
| D012127 | Respiratory Distress Syndrome, Newborn NIH | 0.08 |
| D055371 | Acute Lung Injury NIH | 0.08 |
| D012128 | Respiratory Distress Syndrome, Adult NIH | 0.07 |
| Name (Synonyms) | Correlation |
|---|
Navigate: Correlations HPO
There is one clinical trial.
In COVID-19 times, there has been a large increase in number of people working from home; with limited places to go, an abrupt change to people's lives and lack of knowledge about the dangers of sedentary behaviour (SB), it is important to help workers develop and effortlessly incorporate healthy movement routines to optimize daily productivity and health. The combined lack of knowledge on literature on SB profiles of full time, home-based workers, effects of framing of SB reduction strategies, and strategy preference uncertainty makes for a novel study. This will be a 4-week intervention that looks at whether telling a full time, home-based office worker to do pre-selected strategies using different framing structures to break up their sedentary behaviour (SB) (i.e. sitting) will change their SB profiles. Investigators are looking to see whether having the choice (or not) to choose strategies in an unfamiliar health related selection (preference uncertainty) will create greater changes in SBs. As well, the researchers are incorporating behavioural economics' by altering choice structure in relation to behaviour change and program engagement. Workers' work-related SB will be measured by a device at baseline and on the last week of the intervention. Workers will be provided with an SB educational video to increase knowledge and motivation for change. Any SB changes in relation to productivity, mental wellness, behaviour intentions etc. will also be measured.
Description: measured via ActivPAL
Measure: Change in sedentary behaviour break frequency Time: change from baseline to 4 weeksDescription: measured via ActivPAL
Measure: Change in sedentary behaviour break duration Time: change from baseline to 4 weeksDescription: Short form 36 health survey (SF-36) measured on a 5-point Likert scale from 1 "all of the time" to 5 "None of the time".
Measure: Change in work-related quality of life Time: change from baseline to 6 weeksDescription: Questions regarding work productivity, concentration and focus will be measured with questions adapted from The Health and Work Questionnaire (HWQ). The HWQ is a multidimensional tool used to measure various aspects of productivity. The HWQ consists of 24 questions, several items being multi-part questions with internal consistency scores ranging from alpha = 0.72 to 0.96. The questions are designed to assess work quality, quantity, and efficiency, as well as impatience, concentration/focus, work satisfaction and non-work satisfaction. For the current study, 15 items were chosen from this questionnaire that were relevant to "home-based" office workers. Items will be assessed with a ten-point response scale, tailored to each question (e.g., "my worst ever" to "my best ever").
Measure: Change in Health outcomes Time: change from baseline to 6 weeksDescription: measured with the ActivPAL4
Measure: Change in sitting time Time: change in baseline to 4 weeksDescription: measured with the ActivPAL4
Measure: Change in standing time Time: change in baseline to 4 weeksDescription: measured with the ActivPAL4
Measure: Change in moving time Time: change in baseline to 4 weeksDescription: measured with the ActivPAL4
Measure: Change in prolonged sitting bouts Time: change in baseline to 4 weeksDescription: The validated three-item modified Occupational Sitting and Physical activity questionnaire (OSPAQ). The OSPAQ is a brief instrument reported to have excellent test-retest reliability (intraclass correlation coefficients = 0.73-0.90), moderate criterion validity for time spent sitting and standing (r = 0.65 and 0.49, respectively), and lower validity for time spent walking (r = 0.29). At each assessment period (baseline, week 1, week 2, week 3, week 4 and follow-up), participants will be asked to record both the number of days they were at work and total number of hours they worked in the last 7 days. Participants will then be asked to record a percentage of time spent sitting, standing, and moving (i.e. walking) (cumulative total of 100%) during work hours on a typical workday in the last 7 days.
Measure: Change in percentage of time spent sitting Time: change from baseline to 6 weeksDescription: The validated three-item modified Occupational Sitting and Physical activity questionnaire (OSPAQ). The OSPAQ is a brief instrument reported to have excellent test-retest reliability (intraclass correlation coefficients = 0.73-0.90), moderate criterion validity for time spent sitting and standing (r = 0.65 and 0.49, respectively), and lower validity for time spent walking (r = 0.29). At each assessment period (baseline, week 1, week 2, week 3, week 4 and follow-up), participants will be asked to record both the number of days they were at work and total number of hours they worked in the last 7 days. Participants will then be asked to record a percentage of time spent sitting, standing, and moving (i.e. walking) (cumulative total of 100%) during work hours on a typical workday in the last 7 days.
Measure: Change in percentage of time spent standing Time: change from baseline to 6 weeksDescription: The validated three-item modified Occupational Sitting and Physical activity questionnaire (OSPAQ). The OSPAQ is a brief instrument reported to have excellent test-retest reliability (intraclass correlation coefficients = 0.73-0.90), moderate criterion validity for time spent sitting and standing (r = 0.65 and 0.49, respectively), and lower validity for time spent walking (r = 0.29). At each assessment period (baseline, week 1, week 2, week 3, week 4 and follow-up), participants will be asked to record both the number of days they were at work and total number of hours they worked in the last 7 days. Participants will then be asked to record a percentage of time spent sitting, standing, and moving (i.e. walking) (cumulative total of 100%) during work hours on a typical workday in the last 7 days.
Measure: Change in percentage of time spent moving Time: change from baseline to 6 weeksDescription: measured using a modified version of the SIT-Q 7d;modified the base questionnaire to include domain-specific (work-related) break frequency and duration scores, which were the only items assessed for purposes of this study
Measure: Change in sedentary break frequency Time: change from baseline to 6 weeksDescription: measured using a modified version of the SIT-Q 7d;modified the base questionnaire to include domain-specific (work-related) break frequency and duration scores, which were the only items assessed for purposes of this study
Measure: Change in sedentary break duration Time: change from baseline to 6 weeksAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports