Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
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drug2637 | Nutrition Wiki | 1.00 |
drug1436 | Exercise Wiki | 0.58 |
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D003141 | Communicable Diseases NIH | 0.07 |
D007239 | Infection NIH | 0.05 |
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Navigate: Correlations HPO
There is one clinical trial.
Trial Phase: Phase III: Interventional Trial: Virtual clinics to deliver universal interventions to maintain and improve physical health, nutritional state and psychological wellbeing in people with cancer who are following social distancing guidance: A COVID-19 targeted trial. Indication: Male or female participants, aged over 18 years old with suspicion or confirmed diagnosis of cancer (does not require histological confirmation) Objective: To investigate the efficacy of remote multimodal universal interventions delivered via virtual clinics to improve physical function as measured by the EORTC-QLQ-C30. Secondary Objective: To investigate the efficacy of remote multimodal universal interventions delivered via virtual clinics to improve emotional function, quality of life, participant activation (PAM), behaviour change and the effect it has on health economics (EQ-5D-5L). Exploratory Objective: Overall Survival and adherence to the intervention/advice using validated tools or development of a web-based toolkit.
Description: Physical function will be measured using the EORTC-QLQ-C30. Participants will choose from the choices 1 = Not at all; 2 = A little, 3 = Quite a bit, 4 = Very much
Measure: Physical Function Time: Baseline up to 1 year post enrolmentDescription: Emotional function will be measured using the EORTC-QLQ-C30. Participants will choose from the choices 1 = Not at all; 2 = A little, 3 = Quite a bit, 4 = Very much
Measure: Emotional Function Time: Baseline up to 1 year post enrolmentDescription: EQ-5D-5L is a standardised measure of health status developed by the EuroQol Group. Applicable to a wide range of health conditions and treatments, it provides a simple descriptive profile and a single index value for health status that can be used in the clinical evaluation of health care
Measure: Health related quality of life Time: Baseline up to 1 year post enrolmentDescription: EQ-5D-5L is a standardised measure of health status developed by the EuroQol Group. Applicable to a wide range of health conditions and treatments, it provides a simple descriptive profile and a single index value for health status that can be used in the economic evaluation of health care
Measure: Health economics analysis Time: Baseline up to 1 year post enrolmentDescription: Patients knowledge skills and confidence to manage their own health and care will be measured using the Patient Activation Measure (PAM) Agreement or disagreement with statements. Choice between disagree strongly, disagree, agree, agree strongly and not applicable
Measure: Patient activation Time: Baseline up to 1 year post enrolmentDescription: Measured using the Godin Leisure Time Exercise Questionnaire, a 7-day physical activity recall
Measure: Self-reported physical activity Time: Baseline up to 1 year post enrolmentDescription: In the oncology population where malnutrition prevalence is high, the Patient-Generated Subjective Global Assessment Short Form (PG-SGA SF) is a descriptive screening tool that can provide further information to assist triaging and capture acute change in nutritional state
Measure: Nutrition assessment Time: Baseline up to 1 year post enrolmentDescription: Self-efficacy (confidence) to self-manage chronic disease (SEMCD), measured using the Lorig SEMCD scale A confidence scale that represents the patients confidence that a regular task can be achieved. 1 = Not confident at all and 10= totally confident.
Measure: Self-efficacy for self-management of chronic disease Time: Baseline up to 1 year post enrolmentDescription: Levels of distress as measured by the Emotions Thermometers. Participants will score on a scale where 0 = None and 10 = Extreme
Measure: Distress levels Time: Baseline up to 1 year post enrolmentDescription: The Dukes Activity Status Index is a 12 item self-report measure of functional capacity that can be used to estimate peak oxygen uptake
Measure: Functional capacity Time: Baseline up to 1 year post enrolmentDescription: As measured by the Impact of Event Scale - a 22-item self-report measure of the imapact of a specific traumatic event against the DSM criteria for Post Traumatic Stress Disorder. 0 = Not at all and 4 = Extremely.
Measure: The impact of COVID-19 pandemic on psychological functioning Time: Baseline up to 1 year post enrolmentDescription: Semi-structured interviews with participants and professionals to explore acceptability, usefulness and barriers to delivery/engagement
Measure: Process Evaluation Time: Through study completion, an average of 12 monthsDescription: Overall survival at 1 year following date of enrolment
Measure: Exploratory: Overall survival Time: 1 year post enrolmentDescription: Adherence to intervention advice is defined as number of sessions the participants attends divided by the total number of sessions.
Measure: Exploratory: Adherence to the interventions/advice Time: Baseline up to 1 year post enrolmentAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports