Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
Name (Synonyms) | Correlation | |
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drug4422 | chiropractic team Wiki | 1.00 |
drug4427 | chronic pain team Wiki | 1.00 |
Navigate: Correlations HPO
There is one clinical trial.
Little is known about the physical function outcomes in patients with severe COVID-19 patients who are admitted to Intensive Care Unit (ICU) for invasive mechanical ventilation. The purpose of this study is to evaluate the short-term impact on physical function before hospital discharge in subjects with severe COVID-19 who have survived ICU admission for invasive mechanical ventilation.
Description: Physical examination will be performed to carry out manual muscle testing of strength in 6 different muscle groups of the upper limb and lower limb on both sides of the body.
Measure: Medical Research Council sum score (MRC- SS). Time: < 48 hours before ICU dischargeDescription: Physical examination will be performed to carry out manual muscle testing of strength in 6 different muscle groups of the upper limb and lower limb on both sides of the body.
Measure: Medical Research Council sum score (MRC- SS). Time: < 24 hours before hospital dischargeDescription: The Functional Status Score for the ICU (FSS-ICU) will be used to evaluate 5 functional tasks. Each task is evaluated using an 8-point ordinal scale ranging from 0 (not able to perform) to 7 (complete independence).The total FSS-ICU score ranges from 0 to 35, with higher scores indicating better physical functioning.
Measure: The Functional Status Score for the ICU (FSS-ICU) Time: < 24 hours before hospital dischargeDescription: Age in years
Measure: Age Time: Through study completion, up to 6 monthsDescription: Male vs Female
Measure: Sex Time: Throughout study completion , up to 6 monthDescription: kg/m2
Measure: Body Mass Index Time: Throughout study completion, up to 6 monthsDescription: Baseline mobility
Measure: Baseline mobility Time: First day the patient can cooperate with assessment according to the ' 5 Standard Questions' test.Description: Acute Physiology and Chronic Health Evaluation II score.The APACHE II score ranges from 0 to 71 points. Higher scores correspond to more severe disease and a higher risk of death.
Measure: APACHE II score Time: <24 hours after ICU admissionDescription: Number of days of stay in ICU
Measure: Length of stay in ICU Time: Throughout the study completion, up to 6 monthsDescription: Number of days on mechanical ventilation
Measure: Number of days on mechanical ventilation Time: Throughout the study completion, up to 6 monthsDescription: Clinical or EMG polyneuropathy diagnosis confirmation
Measure: Polyneuropathy diagnosis Time: Throughout the study completion, up to 6 monthsDescription: Number of days on NMB during mechanical ventilation
Measure: Number of days on Neuromuscular Blockers Time: Throughout the study completion, up to 6 monthsDescription: Number of prone positioning episodes during ICU stay
Measure: Episodes of prone positioning Time: Throughout the study completion, up to 6 monthsDescription: Total number of days admitted to hospital
Measure: Length of stay in hospital Time: Throughout the study completion, up to 6 monthsDescription: Home with no follow-up physiotherapy, home with domiciliary or out-patient physiotherapy, rehabilitation facility, care home, transfer to another acute hospital.
Measure: Continuation of care Time: Throughout the study completion, up to 6 monthsAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports