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Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug1351 | Elaborative Reminiscence (ER) Wiki | 1.00 |
| drug3078 | Present Tense Talk (PTT) Wiki | 1.00 |
| Name (Synonyms) | Correlation | |
|---|---|---|
| D001321 | Autistic Disorder NIH | 0.30 |
| D000067877 | Autism Spectrum Disorder NIH | 0.27 |
| Name (Synonyms) | Correlation | |
|---|---|---|
| HP:0000717 | Autism HPO | 0.30 |
| HP:0000729 | Autistic behavior HPO | 0.27 |
Navigate: Correlations HPO
There is one clinical trial.
The trial will be done to determine the impact of a barrier enclosure, COVID (coronavirus disease -19) barrier box on endotracheal intubation attempts, and duration. This study will be a prospective, open-label, randomized controlled trial. A total of 100 patients scheduled for elective surgery will be randomly assigned in two groups (intervention group and control group). Participating attending anesthesiologists will intubate the intervention group patients with COVID barrier box and the control group patients without the box. The anesthesiologists and the intervention group patients will be surveyed about their perception after the surgery. The result of this study will help in decision making about using COVID barrier box to minimize the viral transmission from patients to healthcare workers during the pandemic.
Description: TTI is the time from when the laryngoscope blade passes between the patient's lips until the first upstroke of the capnograph trace. TTI will be measured by a third party observer outside of the operating room.
Measure: Time to tracheal intubation (TTI) Time: This will be measured at the time of intubation for an elective surgical patient. It will take approximately 5 minutes.Description: A first pass success refers to successful insertion of the McGRATH™ videolaryngoscope or endotracheal tube by an anesthesiologist on the first-attempt without withdrawing from the mouth in no longer than 150 seconds.
Measure: First pass success rate Time: This will be measured at the time of intubation for an elective surgical patient within 150 seconds of initiating the first attempt to intubate.Description: This refers to the time from the face mask seal being lifted to the first upstroke of the capnograph trace.
Measure: Total time of airway manipulation Time: This will be measured at the time of intubation for an elective surgical patient. It will take approximately 5 minutes.Description: Participant anesthesiologists will report the number of intubation attempts that were needed to achieve successful intubation.
Measure: Number of intubation attempts Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..Description: Participant anesthesiologists will report the number of operators needed to assist in successfully intubating the participant.
Measure: Number of Operators needed for intubation Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..Description: Participant anesthesiologists will report the number of alternative techniques used for intubation (if any) i.e. repositioning of patient, change of materials (blade, endotracheal (ET) tube, addition of stylette), change in approach (nasotracheal vs orotracheal), use of another technique (Fibreoptic bronchoscopy, intubating laryngeal mask airway (LMA)
Measure: Number of alternative techniques used for intubation Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..Description: Participant anesthesiologists will report the Cormack-Lehane Grade for the first attempt of intubation.
Measure: Cormack-Lehane Grade for the first attempt of intubation Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..Description: Participant anesthesiologists will report if the lifting force applied on laryngoscope blade was normal or increased.
Measure: Lifting force applied on laryngoscope blade Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..Description: Participant anesthesiologists will report if laryngeal pressure, such as Backward Upward Rightward Pressure (BURP) not inclusive of cricoid pressure was applied or not.
Measure: Laryngeal pressure application Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..Description: Participant anesthesiologists will report the vocal cord position (either abduction or adduction).
Measure: Vocal cord position Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..Description: Participant anesthesiologists will report the difficulty experienced during the intubation from a scale of 0 to 10 with 0 being without difficulty and 10 being maximum difficulty.
Measure: Anesthesiologist perception of intubation difficulty Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..Description: Participant anesthesiologists will report any contributors to difficulties in intubation, or state "none", if no difficulties were experienced.
Measure: Anesthesiologist perception of contributors to difficulty in intubation, if any Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..Description: Patients from the intervention group will report the acceptability of COVID barrier box. They will be asked "How acceptable did you find the use of the COVID barrier box?" and respond on a five-point scale (acceptable, slightly acceptable, neutral, slightly unacceptable, unacceptable).
Measure: Patient acceptability of the COVID Barrier Box Time: This question will be asked as part of a short questionnaire administered to patients when they meet the Post Anesthesia Care Unit (PACU) discharge criteria (usually 2 to 5 hours after surgery). It will take about 10 minutes to complete.Description: Patients from the intervention group will report their level of comfort experienced with the use of the COVID barrier box. They will be asked "How comfortable did you find the use of the COVID barrier box?" and will respond on a five-point scale (comfortable, slightly comfortable, neither, slightly uncomfortable, uncomfortable).
Measure: Patient comfort with the COVID Barrier Box Time: This question will be asked as part of a short questionnaire administered to patients when they meet the Post Anesthesia Care Unit (PACU) discharge criteria (usually 2 to 5 hours after surgery). It will take about 10 minutes to complete.Description: Patients from the intervention group will report any comments that they have on the COVID barrier box.
Measure: Patient comments on the COVID Barrier Box Time: This question will be asked as part of a short questionnaire administered to patients when they meet the Post Anesthesia Care Unit (PACU) discharge criteria (usually 2 to 5 hours after surgery). It will take about 10 minutes to complete.Alphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on September 26, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports