Name (Synonyms) | Correlation | |
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drug251 | Argatroban Wiki | 1.00 |
drug1132 | Fondapariniux Wiki | 1.00 |
drug3481 | stem cells Wiki | 1.00 |
drug3009 | Unfractionated heparin Wiki | 0.71 |
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There is one clinical trial.
The purpose of this study is to determine if therapeutic dose anticoagulation (experimental group) improves 30-day mortality in participants with COVID-19 compared to those patients receiving the intermediate dose prophylaxis (control group). Following screening, subjects will be randomized 1:1 to intermediate dose prophylaxis or therapeutic dose anticoagulation treatment arms.Treatment will continue for 28 days, followed by a 6 month follow-up period.
Description: Comparison of number of COVID-19 positive patients who have died within 30 days of starting treatment on each treatment arm
Measure: 30-day mortality Time: 30 daysDescription: Comparison of length of ICU stay in days between each treatment arm.
Measure: Length of Intensive Care Unit (ICU) Stay in Days Time: 6 monthsDescription: Comparison of number of documented VTE, arterial thrombosis and microthrombosis events on each treatment arm
Measure: Number of documented venous thromboembolism (VTE), arterial thrombosis (stroke, myocardial infarction, other) and microthrombosis events Time: 6 monthsDescription: Comparison of major and clinically-relevant non-major bleeding events on each treatment arm, as defined by the International Society of Thrombosis and Haemostasis (ISTH) criteria.
Measure: Number of major and clinically relevant non-major bleeding events Time: 6 months