Name (Synonyms) | Correlation |
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There is one clinical trial.
To date there is no brain imaging and olfactory data available in COVID-19 positive patients with anosmia. By describing the pathophysiological characteristics underlying the olfactory symptoms and clinical characteristics of COVID-19 infection, the study investigators wish to compare the MRI aspects obtained in COVID-19 patients with and without anosmia, in the absence of other underlying neurological disorders.
Description: MRI; Voxels
Measure: Brain regional homogeneity between COVID-19 patients with and without anosmia Time: Day 0Description: MRI; Voxels
Measure: Brain regional homogeneity between COVID-19 patients with and without anosmia Time: Month 3Description: MRI; Voxels
Measure: Topography of supra- or sub-tentorial lesions between COVID-19 patients with and without anosmia Time: Day 0Description: MRI; voxels, value between 0-1
Measure: Fractional anisotropy between COVID-19 patients with and without anosmia Time: Day 0Description: MRI; voxels, value between 0-1
Measure: Fractional anisotropy between COVID-19 patients with and without anosmia Time: Month 3Description: MRI; mm2/s
Measure: Mean diffusivity between COVID-19 patients with and without anosmia Time: Day 0Description: MRI; mm2/s
Measure: Mean diffusivity between COVID-19 patients with and without anosmia Time: Month 3Description: MRI; mm2/s
Measure: Radial diffusivity between COVID-19 patients with and without anosmia Time: Day 0Description: MRI; mm2/s
Measure: Radial diffusivity between COVID-19 patients with and without anosmia Time: Month 3Description: Four questions measured by 0-100 visual analogue scale: how do you rate the quality of your sense of smell/taste normally/today
Measure: Self-assessed olfactory and gustatory test Time: Day 0Description: Four questions measured by 0-100 visual analogue scale: how do you rate the quality of your sense of smell/taste normally/today
Measure: Self-assessed olfactory and gustatory test Time: Day 8Description: Four questions measured by 0-100 visual analogue scale: how do you rate the quality of your sense of smell/taste normally/today
Measure: Self-assessed olfactory and gustatory test Time: Month 1Description: Four questions measured by 0-100 visual analogue scale: how do you rate the quality of your sense of smell/taste normally/today
Measure: Self-assessed olfactory and gustatory test Time: Month 2Description: Ability to smell 1.5ml air freshner on a 0-100 VAS scale (cut-offs: strang (>80), moderate (40-80), attenuated (<40)
Measure: Ability to detect odor Time: Day 0Description: Patient asked to describe whether a pinch of sugar on their tongue taste sweet or salty
Measure: Ability to taste a pinch of sugar Time: Day 0Description: MRI: absence/presence
Measure: Presence of thrombotic and hemorrhagic lesions Time: Day 0Description: MRI: absence/presence
Measure: Presence of thrombotic and hemorrhagic lesions Time: Month 3Description: Short Ti Inversion Recovery (STIR); presence/absence
Measure: Presence of lesions with hyperintensity Time: Day 0Description: Short Ti Inversion Recovery (STIR); presence/absence
Measure: Presence of lesions with hyperintensity Time: Month 3Description: beta voxels
Measure: Projection network analysis of all patients Time: Day 0Description: beta voxels
Measure: Projection network analysis of all patients Time: Month 3Description: beta voxels
Measure: Blinded independent component analysis of all patients Time: Day 0Description: beta voxels
Measure: Blinded independent component analysis of all patients Time: Month 3Description: beta voxels
Measure: default mode network analysis of all patients Time: Day 0Description: beta voxels
Measure: default mode network analysis of all patients Time: Month 3Description: beta voxels
Measure: executive control network analysis of all patients Time: Day 0Description: beta voxels
Measure: executive control network analysis of all patients Time: Month 3