CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Placebo GroupWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (3)


Name (Synonyms) Correlation
drug1043 Experimental Group Wiki 1.00
drug2223 Presatovir Wiki 0.50
drug2122 Placebo Wiki 0.05

Correlated MeSH Terms (3)


Name (Synonyms) Correlation
D018357 Respiratory Syncytial Virus Infections NIH 0.41
D003141 Communicable Diseases NIH 0.08
D007239 Infection NIH 0.05

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Atovaquone for Treatment of COVID-19

The purpose of the current study is to accelerate the use of a clinically available therapeutic already FDA-approved for other indications in the setting of pandemic COVID-19 addressing a serious and emergent unmet medical need. This is a randomized, double-blind study of atovaquone therapy in adult participants hospitalized with COVID-19. Approximately 60 participants who meet all eligibility criteria may be randomized in a 2:1 atovaquone/placebo ratio into one of the following treatment groups: Treatment Group 1: continued standard of care therapy together with an oral dose of 1500 mg atovaquone twice daily (administered with a meal or snack) for up to 10 days Treatment Group 2: continued standard of care therapy together with matching placebo

NCT04456153 COVID-19 Drug: Experimental Group Drug: Placebo Group

Primary Outcomes

Description: Log copy number/ml by RT-PCR) from saliva collection at Day 8 from trial entry, or at hospital discharge

Measure: Viral Load

Time: Up to 16 days


No related HPO nodes (Using clinical trials)