There is one clinical trial.
To capture the natural history of COVID-19 associated olfactory dysfunction as measured by two patient reported outcome measures (SNOT-22, QOD-NS) and a 6-week BSIT with a comparison to an intervention arm receiving daily omega-3 supplements.
Description: Brief Smell Identification Test (BSIT) is a 12-item instrument, full range score from 0 to 12, higher score indicates better olfactory performances.
Measure: Brief Smell Identification Test (BSIT) Time: Week 0Description: Brief Smell Identification Test (BSIT) is a 12-item instrument, full range score from 0 to 12, higher score indicates better olfactory performances.
Measure: Brief Smell Identification Test (BSIT) Time: 6 weeks after beginning to take supplementsDescription: The modified Brief Questionnaire of Olfactory Dysfunction - Negative Statements (QOD-NS) survey is a 17-item instrument, each item graded on a scale from 0 to 3, with total scale range from 0 to 51. Higher score indicates better olfactory-specific quality of life (QOL).
Measure: Modified Brief Questionnaire of Olfactory Dysfunction (mQOD-NS) Time: 1 week after softgel initiationDescription: The modified Brief Questionnaire of Olfactory Dysfunction - Negative Statements (QOD-NS) survey is a 17-item instrument, each item graded on a scale from 0 to 3, with total scale range from 0 to 51. Higher score indicates better olfactory-specific quality of life (QOL).
Measure: Modified Brief Questionnaire of Olfactory Dysfunction (mQOD-NS) Time: 2 weeks after softgel initiationDescription: The modified Brief Questionnaire of Olfactory Dysfunction - Negative Statements (QOD-NS) survey is a 17-item instrument, each item graded on a scale from 0 to 3, with total scale range from 0 to 51. Higher score indicates better olfactory-specific quality of life (QOL).
Measure: Modified Brief Questionnaire of Olfactory Dysfunction (mQOD-NS) Time: 4 weeks after softgel initiationDescription: The modified Brief Questionnaire of Olfactory Dysfunction - Negative Statements (QOD-NS) survey is a 17-item instrument, each item graded on a scale from 0 to 3, with total scale range from 0 to 51. Higher score indicates better olfactory-specific quality of life (QOL).
Measure: Modified Brief Questionnaire of Olfactory Dysfunction (mQOD-NS) Time: 6 weeks after softgel initiationDescription: Sino-Nasal Outcome Test (SNOT-22) is a 22-item instrument, total scale range from 0 to 110, higher score indicates more severe QOL impact.
Measure: Sinonasal Outcomes Test (SNOT-22) Time: 1 week after softgel initiationDescription: Sino-Nasal Outcome Test (SNOT-22) is a 22-item instrument, total scale range from 0 to 110, higher score indicates more severe QOL impact.
Measure: Sinonasal Outcomes Test (SNOT-22) Time: 2 weeks after softgel initiationDescription: Sino-Nasal Outcome Test (SNOT-22) is a 22-item instrument, total scale range from 0 to 110, higher score indicates more severe QOL impact.
Measure: Sinonasal Outcomes Test (SNOT-22) Time: 4 weeks after softgel initiationDescription: Sino-Nasal Outcome Test (SNOT-22) is a 22-item instrument, total scale range from 0 to 110, higher score indicates more severe QOL impact.
Measure: Sinonasal Outcomes Test (SNOT-22) Time: 6 weeks after softgel initiation