Correlated Drug Terms (0)

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	Name (Synonyms)	Correlation

Correlated MeSH Terms (1)

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	Name (Synonyms)	Correlation
D006258	Head and Neck Neoplasms NIH	0.50

Correlated HPO Terms (1)

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	Name (Synonyms)	Correlation
HP:0012288	Neoplasm of head and neck HPO	0.50

Primary Outcomes

Description: Change in number of participants meeting Guidelines for Physical Activity of 150 minutes per week of moderate intensity exercise, based on accelerometer data from commercially-available activity tracker.

Measure: Physical Activity Minutes Per Week

Time: Baseline to one-year

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Secondary Outcomes

Description: Change in body mass index (BMI)

Measure: Body Composition

Time: Baseline to post 12-week exercise intervention

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Description: Change in 6-minute walk test (m) or 2 minute step test (steps) results

Measure: Aerobic Endurance

Time: Baseline to post 12-week exercise intervention

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Description: Change in hand-grip dynamometry (kg)

Measure: Upper extremity grip strength

Time: Baseline to post 12-week exercise intervention

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Description: Change in sit-to-stand (number of repetitions in 30 seconds)

Measure: Functional performance test

Time: Baseline to post 12-week exercise intervention

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Description: Change in active shoulder flexion range of motion (degrees)

Measure: Upper extremity flexibility

Time: Baseline to post 12-week exercise intervention

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Description: Change in sit-and-reach test (cm)

Measure: Lower extremity flexibility

Time: Baseline to post 12-week exercise intervention

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Description: Change in one legged stance test (seconds)

Measure: Balance

Time: Baseline to post 12-week exercise intervention

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Description: Change in fatigue, mood, and QOL, recorded via m-Health app

Measure: Symptom tracking

Time: Baseline to one year

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Description: Change in Edmonton Symptom Assessment Scale. - scale is from 0-10, where 0 means the symptom is absent and 10 means the worst possible severity of the symptom is being experienced.

Measure: Cancer related symptoms

Time: Baseline to one year

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Description: Change in Godin Leisure Time Exercise Questionnaire

Measure: Subjective reporting of average weekly physical activity

Time: Baseline to one year

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Description: Change in EuroQual - 5Dimensions (EQ-5D) tool - first section is a questionniare; last section uses a scale from 0-100, where 0 means the worst health imaginable and 100 means the best health imaginable.

Measure: General Health-related Quality of Life

Time: Baseline to one year

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Description: Change in Functional Assessment of Chronic Illness Therapy - Fatigue subscale - scale is from 0-4, where 0 means "not at all" and 4 means "very much".

Measure: Fatigue

Time: Baseline to one year

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Description: Change in Functional Assessment of Cancer Therapy - General subscale - scale is from 0-4, where 0 means "not at all" and 4 means "very much".

Measure: General well-being

Time: Baseline to one year

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Description: Change in Functional Assessment of Cancer Therapy - Cognitive subscale - scale is from 0-4, where 0 means "never" and 4 means "several times a day" (experiencing symptoms).

Measure: Cognition

Time: Baseline to one year

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Description: Change in Exercise Barriers and Facilitators questionnaire

Measure: Barriers and facilitators to exercise participation

Time: Baseline to one year

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Description: Adherence to exercise programming (attendance at sessions)

Measure: Exercise adherence

Time: Baseline to one year

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Description: RE-AIM: program reach, effectiveness, adoption, implementation and maintenance

Measure: Program implementation and evaluation

Time: Baseline to one year

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HP:0012288: Neoplasm of head and neck

Genes 25

FOXE1 RHBDF2 SDHB KIT HABP2 SDHA KIT MINPP1 FH CTHRC1 APC SDHC RHBDF2 RAD21 STK11 ASCC1 PDGFRA STAT1 RNF6 APC TGFBR2 WWOX MSR1 RSPRY1 DLEC1

Protein Mutations 2

E10A P13K

SNP 2

rs11045585 rs12762549