Name (Synonyms) | Correlation |
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Name (Synonyms) | Correlation | |
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D007154 | Immune System Diseases NIH | 0.41 |
D012128 | Respiratory Distress Syndrome, Adult NIH | 0.08 |
Name (Synonyms) | Correlation |
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There is one clinical trial.
DESIGN Longitudinal prospective observational multicentre study. Primary objective: Understand the immune mechanisms driving COVID-19 disease in patients with a history of lung disease
Description: Anti-viral cytokine protein concentration in blood samples by ELISA
Measure: Anti-viral cytokine levels in blood samples in chronic respiratory disease associated with susceptibility to severe COVID-19 infection Time: Through study completion an average of 1 yearDescription: Inflammatory cytokine protein concentration in sputum samples by ELISA
Measure: Anti-viral cytokines profiles within sputum samples in chronic respiratory disease associated with susceptibility to severe COVID-19 infection Time: Through study completion an average of 1 yearDescription: Inflammatory cytokine protein concentration in nasal lavage samples by ELISA
Measure: Anti-viral cytokine profiles within nasal lavage samples in chronic respiratory disease associated with susceptibility to severe COVID-19 infection associated with susceptibility to severe COVID-19 infection Time: Through study completion an average of 1 yearDescription: Inflammatory gene expression in upper airway respiratory epithelial cells by RNA sequencing.
Measure: Expression of inflammatory gene expression in upper respiratory epithelial airway cells using nasal brush specimens in chronic respiratory disease associated with susceptibility to severe COVID-19 infection Time: Through study completion an average of 1 yearDescription: Analysis of viral components recognized by the adaptive immune system
Measure: Identify the T cell antigens and B cell epitopes in chronic respiratory disease associated with susceptibility to severe COVID-19 infection Time: Through study completion an average of 1 yearDescription: Cytokine protein concentration following PBMC stimulation to pathogen recognition receptor agonists by Elispot
Measure: Peripheral blood mononuclear cell (PBMC) interferon mediated immune responses to pathogen recognition receptor agonists in chronic respiratory disease associated with susceptibility to severe COVID-19 infection Time: Through study completion an average of 1 yearDescription: Analysis of endothelial function
Measure: Identify endothelial function in chronic respiratory disease associated with susceptibility to severe COVID-19 infection using EndoPAT testing Time: Through study completion an average of 1 yearDescription: Serum and plasma protein concentration of endothelial cell inflammation biomarkers by ELISA
Measure: Endothelial cell inflammation biomarkers in chronic respiratory disease associated with susceptibility to severe COVID-19 infection Time: Through study completion an average of 1 yearDescription: Analysis of sputum microbiome
Measure: Identify sputum 16S rRNA and ITS sequences in chronic respiratory disease associated with susceptibility to severe COVID-19 infection Time: Through study completion an average of 1 yearDescription: Analysis of nasal microbiome
Measure: Identify nasal lavage 16S rRNA and ITS sequences in chronic respiratory disease associated with susceptibility to severe COVID-19 infection Time: Through study completion an average of 1 yearDescription: Study participant survey
Measure: Identify quality of life markers in chronic respiratory disease associated with susceptibility to severe COVID-19 infection Time: Through study completion an average of 1 year