CovidResearchTrials by Shray Alag

CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)

Zinc gluconateWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (3)

Name (Synonyms) Correlation
drug2851 Telemedicine FU Wiki 1.00
drug29 25-OH cholecalciferol Wiki 1.00
drug1962 Office FU Wiki 1.00

Correlated MeSH Terms (2)

Name (Synonyms) Correlation
D054058 Acute Coronary Syndrome NIH 0.45
D013577 Syndrome NIH 0.10

Correlated HPO Terms (0)

Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials

1 Impact of Zinc and Vitamin D3 Supplementation on the Survival of Institutionalized Aged Patients Infected With COVID-19

Mortality from Covid-19 increases with age, reaching 14.8% from the age of 80. The severity of the infection is linked to the acute respiratory distress syndrome (ARDS) which requires intensive care. ARDS is the consequence of the reactional inflammatory storm that damages the lungs. Aged subjects are particularly prone to zinc and vitamin D deficiency. These two micronutrients are able to modulate the immune response by reducing the inflammatory storm. The hypothesis is that supplementation with zinc and vitamin D would reduce the inflammatory reaction which worsens ARDS and leads to the death of subjects infected with Covid-19.

NCT04351490 SARS-CoV 2 Dietary Supplement: Zinc gluconate Dietary Supplement: 25-OH cholecalciferol

Primary Outcomes

Measure: Survival rate in asymptomatic subjects at inclusion

Time: Two months after inclusion

Secondary Outcomes

Measure: Survival rate in symptomatic subjects at inclusion

Time: Two months after inclusion

Description: symptomatic subjects and asymptomatic subjects

Measure: Survival rate in overall subjects

Time: Two months after inclusion

Measure: Cumulative incidence of Covid-19 infection in asymptomatic subjects at inclusion

Time: Within two months after inclusion

No related HPO nodes (Using clinical trials)