Correlated Drug Terms (2)

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	Name (Synonyms)	Correlation
drug3273	fsfi survey Wiki	1.00
drug2122	Placebo Wiki	0.05

Correlated MeSH Terms (5)

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	Name (Synonyms)	Correlation
D012120	Respiration Disorders NIH	0.26
D012140	Respiratory Tract Diseases NIH	0.21
D013577	Syndrome NIH	0.10
D045169	Severe Acute Respiratory Syndrome NIH	0.05
D018352	Coronavirus Infections NIH	0.04

Correlated HPO Terms (0)

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	Name (Synonyms)	Correlation

Primary Outcomes

Measure: A composite outcome of death or ICU admission or mechanical ventilation at day 14.

Time: 14 days

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Secondary Outcomes

Measure: A composite outcome of death or ICU admission or mechanical ventilation at day 28

Time: 28 days

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Description: ICU admission, mechanical ventilation, death or consent withdrawal

Measure: Time to treatment failure

Time: 28 days

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Measure: Overall survival at days 14 and 28

Time: 14 and 28 days

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Measure: Cumulative incidence of ICU admission rate at days 14 and 28

Time: 14 and 28 days

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Measure: Cumulative incidence of mechanical ventilation at days 14 and 28

Time: 14 and 28 days

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Measure: Duration of hospital stay

Time: 28 days

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Measure: Duration of ICU stay

Time: 28 days

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Measure: Duration of mechanical ventilation

Time: 28 days

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Measure: Duration of non-invasive ventilation

Time: 28 days

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Measure: Secondary hemophagocytic syndrome rate

Time: 28 days

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Measure: Cumulative incidence nosocomial infection rate at days 14 and 28

Time: 14 and 28 days

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Measure: Incidence of discontinuation of oxygen supplementation at days 14 and 28

Time: 14 and 28 days

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Measure: Rate of grade 1-2 and 3-5 emerging adverse events at day 28

Time: 28 days

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Measure: Cumulative dose of methylprednisolone at days 14 and 28

Time: 14 and 28 days

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Measure: Change in PaO2/FiO2 ratio from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in interleukin 6 levels [pg/mL] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in d-dimer levels [ng/mL] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in fibrinogen levels [mg/dL] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in ferritin levels [ng/mL] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in C reactive protein levels [mg/L] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in alanine aminotransferase [U/L] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in aspartate aminotransferase [U/L] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in creatinine levels [mg/dL] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in glucose levels [mg/dL] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in hemoglobin levels [g/dL] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in platelet count [x10ˆ3/mmˆ3] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in absolute neutrophil count [x10ˆ3/mmˆ3] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in absolute neutrophil count [/mmˆ3] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in absolute lymphocyte count [/mmˆ3] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in prothrombin time ratio from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in partial thromboplastin time ratio from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in bilirubin [mg/dl] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in lactate dehydrogenase [U/L] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in CPK-MB [ng/mL] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in troponin [ng/mL] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in von Willebrand factor antigen level (VWF:Ag) [%] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in von Willebrand factor activity (ristocetin cofactor) [%] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in ADAMTS-13 [%] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in von Willebrand multimeters from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in plasminogen activator inhibitor-1 levels [ng/mL] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in E-selectin levels [ng/mL] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in P-selectin levels [ng/mL] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in endothelin [fmol/mL] from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in circulating microparticles from baseline to days 14 and 28

Time: 14 and 28 days

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Measure: Change in thromboelastography from baseline to days 14 and 28

Time: 14 and 28 days

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