CovidResearchTrials by Shray Alag

CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)

GAMUNEX-CWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (2)

Name (Synonyms) Correlation
drug3282 home spirometry Wiki 1.00
drug2683 Standard Medical Treatment Wiki 0.58

Correlated MeSH Terms (1)

Name (Synonyms) Correlation
D018352 Coronavirus Infections NIH 0.04

Correlated HPO Terms (0)

Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials

1 A Multicenter, Randomized, Open-label Parallel Group Pilot Study to Evaluate Safety and Efficacy of High Dose Intravenous Immune Globulin (IVIG) Plus Standard Medical Treatment (SMT) Versus SMT Alone in Subjects With COVID-19 Requiring Admission to the Intensive Care Unit

The purpose of the study is to determine if a high dose of IVIG plus SMT can reduce all-cause mortality versus SMT alone in hospitalized participants with COVID-19 requiring admission to the ICU through Day 29.

NCT04480424 COVID-19 Biological: GAMUNEX-C Drug: Standard Medical Treatment
MeSH:Coronavirus Infections

Primary Outcomes

Measure: All-Cause Mortality Rate Through Day 29

Time: Up to Day 29

Secondary Outcomes

Measure: Time to Actual ICU Discharge

Time: Day 1 through Day 29

Measure: Duration of Mechanical Ventilation

Time: Day 1 through Day 29

Measure: Time to Actual Hospital Discharge

Time: Day 1 through Day 29

Measure: Duration of Any Oxygen Use

Time: Day 1 through Day 29

Measure: Absolute Value and Mean Change from Baseline in Ordinal Scale

Time: Day 1 through Day 29

Measure: Percentage of Participants in Each Severity Category of the 7-Point Ordinal Scale

Time: Day 15, Day 29

Measure: Overall Number of Participants who Develop Acute Respiratory Distress Syndrome (ARDS)

Time: Up to Day 29

Measure: Number of Participants who Develop ARDS Distributed by Severity

Time: Up to Day 29

Measure: Change from Baseline in Sequential Organ Failure Assessment (SOFA) Score

Time: Days 5, 15, and 29

Measure: Change from Baseline in National Early Warning Score (NEWS)

Time: Day 1 through Day 29

Measure: Time to Clinical Response as Assessed by: NEWS ≤ 2 Maintained for 24 hours

Time: Day 1 through Day 29

No related HPO nodes (Using clinical trials)