Name (Synonyms) | Correlation | |
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drug1248 | High PEEP with end inspiratory pause Wiki | 1.00 |
drug1249 | High PEEP without end inspiratory pause Wiki | 1.00 |
drug1615 | Low PEEP - FiO2 low Wiki | 1.00 |
Name (Synonyms) | Correlation | |
---|---|---|
D012128 | Respiratory Distress Syndrome, Adult NIH | 0.08 |
Name (Synonyms) | Correlation |
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There is one clinical trial.
The combination of different ventilatory strategies and its effects on respiratory mechanics and gas exchange in patients under mechanical ventilation with acute respiratory distress syndrome secondary to coronavirus-19 has been scarcely described.
Description: The driving transpulmonary pressure will be evaluated between the high and low PEEP condition using the formula: driving transpulmonary pressure = driving airway pressure - driving esophageal pressure (cmH2O).
Measure: Driving transpulmonary pressure (cmH2O) Time: 10 minutesDescription: The Bohr dead space fraction will be evaluated with high PEEP between the condition with end inspiratory pause and with no end inspiratory pause application using the formula: Bohr dead space fraction = Alveolar pressure of CO2 (PACO2) - Expired pressure of CO2 (PECO2) / PACO2
Measure: Bohr dead space fraction (%) Time: 10 minutesDescription: The shunt fraction will be evaluated with low PEEP between the condition with high fraction of oxygen to achieve a saturation goal of 96-98% and the condition with low fraction of oxygen to achieve a saturation goal of 88-92%. The shunt fraction will be calculated using the formula: Qs/Qt = (capillary oxygen content - arterial oxygen content)/(capillary oxygen content - venous oxygen content)
Measure: Shunt fraction (%) Time: 10 minutes