Name (Synonyms) | Correlation | |
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drug687 | Clofazimine Wiki | 0.71 |
drug892 | Dietary intake, body composition, lifestyle, and CVD risk factors Wiki | 0.71 |
drug1784 | Moxibustion plus Cupping Wiki | 0.71 |
drug2443 | Ribavirin Wiki | 0.35 |
Name (Synonyms) | Correlation | |
---|---|---|
D001835 | Body Weight NIH | 0.50 |
D003289 | Convalescence NIH | 0.32 |
Name (Synonyms) | Correlation |
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There are 2 clinical trials
To conduct an open-label randomized controlled trial on a short course of interferon β-1b and clofazimine combination treatment for patients hospitalized for COVID-19 infection. To assess its safety and clinical efficacy.
Description: Time to complete alleviation of symptoms as defined by NEWS of 0 maintained for 24 hours
Measure: Clinical alleviation of symptoms Time: 7 daysDescription: Length of hospitalisation
Measure: Hospitalisation Time: 14 daysDescription: Time to negative nasopharyngeal swab, throat saliva and sputum viral load by RT-PCR
Measure: Time to negative viral load Time: 7 daysDescription: Cytokine/ chemokine changes
Measure: Inflammatory changes Time: 7 daysDescription: One month mortality rate
Measure: Mortality Time: 30 daysDescription: Adverse events during and shortly after treatment
Measure: Adverse events Time: 30 daysAs of 1 July 2020, more than 10 million people been confirmed to have infected by SARS-CoV-2, resulting in more than 500,000 deaths. No specific antiviral treatment for the SARS-CoV-2 is currently available, but existing medication could be repurposed. The investigators therefore propose to conduct an open-label randomized controlled trial on a short course of interferon β-1b and ribavirin combination treatment for patients hospitalized for COVID-19 infection.
Description: Time to complete alleviation of symptoms as defined by NEWS2 of 0 maintained for 24 hours
Measure: Clinical symptoms alleviation Time: 7 daysDescription: Length of hospitalisation
Measure: Hospitalisation Time: 14 daysDescription: Time to negative nasopharyngeal swab and throat saliva viral load by RT-PCR
Measure: Time to negative viral load Time: 7 daysDescription: Cytokine/ chemokine changes
Measure: Inflammatory changes Time: 7 daysDescription: One month mortality rate
Measure: Mortality Time: 30 daysDescription: Adverse events and serious adverse events within 30 days of treatment
Measure: Adverse events and serious adverse events Time: 30 days