CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Extravascular Lung Water IndexWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (3)


Name (Synonyms) Correlation
drug2278 Pulmonary Vascular Permeability Index Wiki 1.00
drug323 Açaí palm berry extract - natural product Wiki 1.00
drug2122 Placebo Wiki 0.05

Correlated MeSH Terms (4)


Name (Synonyms) Correlation
D011654 Pulmonary Edema NIH 0.71
D055371 Acute Lung Injury NIH 0.10
D012127 Respiratory Distress Syndrome, Newborn NIH 0.09
D012128 Respiratory Distress Syndrome, Adult NIH 0.08

Correlated HPO Terms (1)


Name (Synonyms) Correlation
HP:0100598 Pulmonary edema HPO 0.71

There is one clinical trial.

Clinical Trials


1 Comparison of Extra Vascular Lung Water Index in Covid-19 ARDS and "Typical"ARDS Patients

Covid-19 also primarily affects endothelium that line up the alveoli. The resulting hypoxemia may differ from "typical" Acute Respiratory Distress Syndrome (ARDS) due to maldistribution of perfusion related to the ventilation. Thus, pathophysiology of Covid-19 ARDS is different, which requires different interventions than typical ARDS. The investigators will assess whether extravascular lung water index and permeability of the alveolar capillary differs from typical ARDS with transpulmonary thermodilution (TPTD) technique. Extravascular Lung Water Index (EVLWI) and Pulmonary Vascular Permeability Index (PVPI) will be compared.

NCT04508933 Respiratory Distress Syndrome, Adult Ventilation Perfusion Mismatch Pulmonary Edema Covid19 Device: Extravascular Lung Water Index Device: Pulmonary Vascular Permeability Index
MeSH:Respiratory Distress Syndrome, Newborn Respiratory Distress Syndrome, Adult Pulmonary Edema Acute Lung Injury
HPO:Pulmonary edema

Primary Outcomes

Description: The amount of fluid accumulated in the lung measured by transpulmonary thermodilution (ml/kg)

Measure: Extravascular Lung Water Index

Time: 1 day

Description: Integrity of the alveolocapillary barrier measured by transpulmonary thermodilution

Measure: Pulmonary vascular permeability index

Time: 1 day


Related HPO nodes (Using clinical trials)