CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Virtual Group ExerciseWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (3)


Name (Synonyms) Correlation
drug2652 Socialization Wiki 1.00
drug1933 Nutrition Consult and Protein Supplementation Wiki 1.00
drug1708 Medication Review Wiki 1.00

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D000073496 Frailty NIH 0.41

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 GERAS Frailty Rehabilitation at Home: Virtual Bundled Care for Seniors Who Are Frail to Build Strength and Resilience During COVID-19

The coronavirus disease 2019 (COVID-19) pandemic is keeping people apart, which can take a toll on physical and mental health. Many healthcare professionals are concerned vulnerable seniors may become deconditioned, which substantially increases risk of health complications and need for hospitalization. To address the immediate impact of COVID-19 policies (i.e., physical distancing, reduced access to care), the GERAS Frailty Rehabilitation model will be adapted to be delivered remotely in the homes of vulnerable seniors. The investigators' aim is to understand how to best build resilience among vulnerable seniors in the community through at-home rehabilitation services (socialization, exercise, nutrition, and medication support).

NCT04500366 Frailty Behavioral: Socialization Behavioral: Virtual Group Exercise Combination Product: Nutrition Consult and Protein Supplementation Behavioral: Medication Review
MeSH:Frailty

Primary Outcomes

Description: Assessed by the 5x Sit-to-Stand (time to complete). Faster times to complete indicate better performance.

Measure: Change in Physical Function

Time: Baseline and 12 Weeks Post-Intervention

Description: Assessed by the Depression Anxiety Stress Scale (DASS-21). Higher scores indicate greater risk of depression, anxiety and stress [depression, anxiety, stress subscores range 0-21].

Measure: Change in Mental Health

Time: Baseline and 12 Weeks Post-Intervention

Secondary Outcomes

Description: Assessed by the SARC-F - Self-reported strength, assistance with walking, rising from a chair, climbing stairs and falls. Higher scores indicate greater level of sarcopenia [range 0-10].

Measure: Change in Sarcopenia

Time: Baseline and 12 Weeks Post-Intervention

Description: Assessed by the Fit-Frailty Index. Higher scores indicate greater degree of frailty [range 0-1].

Measure: Change in Frailty

Time: Baseline and 12 Weeks Post-Intervention

Description: Balance confidence will be assessed using the Activities-specific Balance Confidence Scale (ABCs). Higher scores indicate greater balance confidence [range 0-100].

Measure: Change in Self-Efficacy

Time: Baseline and 12 Weeks Post-Intervention

Description: Assessed by the interRAI Community Rehab Assessment - Self-Report

Measure: Self-Reported Change in Function, Health and Well-Being

Time: Baseline and 12 Weeks Post-Intervention

Description: Assessed by the interRAI Community Rehab Assessment - Clinician-Completed

Measure: Clinician-Reported Change in Function, Health and Well-Being

Time: Baseline and 12 Weeks Post-Intervention

Description: Assessed by the Borg Rate of Perceived Exertion after exercise. Higher scores indicate greater level of exertion [range 6-20].

Measure: Change in Fitness

Time: Weekly up to 12 weeks

Description: Assessed using a program questionnaire in accordance with the Kirkpatrick 5-Level Evaluation Model. Scores will be on a 5-point Likert scale ranging from "Strongly Disagree" to "Strongly Agree".

Measure: Program Satisfaction

Time: 12 Weeks Post-Intervention

Description: Number of emergency room visits will be recorded. Higher number of emergency room visits indicates higher healthcare utilization.

Measure: Change in Emergency Room Visits

Time: Baseline and 12 Weeks Post-Intervention

Description: Number of hospitalizations will be recorded. Higher number of hospitalizations indicates higher healthcare utilization.

Measure: Change in Hospitalizations

Time: Baseline and 12 Weeks Post-Intervention

Description: Number of calls to 911 will be recorded. Higher number of calls indicates higher healthcare utilization.

Measure: Change in Number of Calls to 911

Time: Baseline and 12 Weeks Post-Intervention

Other Outcomes

Description: Assessed by the number of individuals who participated. Target reach is 70 participants.

Measure: Feasibility Outcome #1 - Reach of intervention

Time: 12 Weeks Post-Intervention

Description: Assessed by number of referral sites. Target is 5 referral sites.

Measure: Feasibility Outcome #2 - Adoption of the Intervention

Time: 12 Weeks Post-Intervention

Description: Assessed by the number of individuals who completed the intervention. Higher number of individuals completing the study indicates greater success in implementation.

Measure: Feasibility Outcome #3 - Implementation of the Intervention

Time: 12 Weeks Post-Intervention

Description: Assessed by the number of referral sites continuing with a second cohort. Greater number of referral sites continuing with a second cohort indicates greater maintenance.

Measure: Feasibility Outcome #4 - Maintenance of the Intervention

Time: 12 Weeks Post-Intervention


No related HPO nodes (Using clinical trials)