CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Written Summary of RoundsWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (0)


Name (Synonyms) Correlation

Correlated MeSH Terms (2)


Name (Synonyms) Correlation
D040921 Stress Disorders, Traumatic NIH 0.19
D013313 Stress Disorders, Post-Traumatic NIH 0.18

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Relieving the Burden of Psychological Symptoms Among Families of Critically Ill Patients With COVID-19

Families of patients in Intensive Care Units (ICUs) are at increased risk for developing psychological symptoms that can last for months after the patient is discharged. These symptoms can have significant impact on both the patient and family member's quality of life. The investigators have found that families of patients admitted to the Rush University Medical Center ICU during to the COVID-19 pandemic were more likely to develop clinically significant psychological symptoms than families of patients admitted prior to the COVID-19 pandemic. The investigators suspect that this finding is due in part to the hospital-wide no visitation policy that altered our standard communication practices and may have prevented families from being active participants in the patient's medical care. The goals of this project are 1) to determine the prevalence of psychological disorders among families of COVID-19 patients after ICU discharge 2) to determine the characteristics of ICU care that were associated with the development of psychological disorders among family members and 3) to pilot a program in which families with psychological disorders after ICU discharge receive therapy from mental health professionals.

NCT04501445 Family Members Post Intensive Care Unit Syndrome Post Traumatic Stress Disorder Behavioral: Written Summary of Rounds
MeSH:Stress Disorders, Traumatic Stress Disorders, Post-Traumatic

Primary Outcomes

Description: Score on Impact of Events Scale Revised (IES-R) questionnaire. 22 questions. Score 0-88 with higher scores indicating more stress.

Measure: Symptoms of Post-Traumatic Stress Disorder (PTSD) initial

Time: Measured once upon enrollment

Description: Score on Hospital Anxiety and Depression Scale (HADS). Total score 0-21 for anxiety (7 questions) and 0-21 for depression (7 questions). Higher scores indicate greater symptom burden.

Measure: Symptoms of Anxiety and Depression initial

Time: Measured once upon enrollment

Secondary Outcomes

Description: Score on the Critical Care Family Needs Inventory (CCFNI) questionnaire. 14 questions. Total score range 14-56 with lower scores indicating better satisfaction.

Measure: Surrogate Satisfaction with the Patient's ICU Care:

Time: Measured once upon enrollment

Description: Score on Hospital Anxiety and Depression Scale (HADS). Total score 0-21 for anxiety (7 questions) and 0-21 for depression (7 questions). Higher scores indicate greater symptom burden.

Measure: Symptoms of Post-Traumatic Stress Disorder (PTSD) final

Time: Measured after behavioral intervention (6-12 weeks after enrollment)

Description: Score on Hospital Anxiety and Depression Scale (HADS). Total score 0-21 for anxiety (7 questions) and 0-21 for depression (7 questions). Higher scores indicate greater symptom burden.

Measure: Symptoms of Anxiety and Depression final

Time: Measured after behavioral intervention (6-12 weeks after enrollment)

Description: Qualitative analysis of phone interview to determine the presence and reason(s) for psychological symptoms

Measure: Interview initial

Time: Measured once upon enrollment

Description: Qualitative analysis of phone interview to determine the presence and reason(s) for psychological symptoms

Measure: Interview final

Time: Measured after behavioral intervention (6-12 weeks after enrollment)


No related HPO nodes (Using clinical trials)