CovidResearchTrials by Shray Alag

CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)

FisetinWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (7)

Name (Synonyms) Correlation
drug303 Avdoralimab Wiki 1.00
drug658 Chloroquine analog (GNS651) Wiki 1.00
drug1773 Monalizumab Wiki 1.00
drug1883 Nivolumab Wiki 0.58
drug2707 Standard of care Wiki 0.23
drug2928 Tocilizumab Wiki 0.17
drug2122 Placebo Wiki 0.05

Correlated MeSH Terms (3)

Name (Synonyms) Correlation
D009362 Neoplasm Metastasis NIH 0.50
D003141 Communicable Diseases NIH 0.08
D007239 Infection NIH 0.05

Correlated HPO Terms (0)

Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials

1 COVID-FISETIN: A Phase 2 Placebo-Controlled Pilot Study in Covid-19 of Fisetin to Alleviate Dysfunction and Excessive Inflammatory Response in Hospitalized Adults

The purpose of this study is to test whether Fisetin, a senolytic drug, can assist in preventing an increase in the disease's progression and alleviate complications of coronavirus due to an excessive inflammatory reaction.

NCT04476953 COVID-19 Drug: Placebo Drug: Fisetin

Primary Outcomes

Description: Number of participants to experience serious adverse events and hypersensitivity reactions.

Measure: Serious Adverse Events

Time: 6 months

Description: change in oxygenation levels as measured by S/F ratio (SPO2/FiO2)

Measure: Change in oxygenation status

Time: baseline, Day 3, 7, 10, 14, 17 and 30; Months 3 and 6

Secondary Outcomes

Description: Number of participants to progress to severe or critical classification measure by the WHO/ NIH Baseline Severity Classification criteria descriptions of SARS-CoV-2 infection without symptoms, Mild COVID-19 (CoV), Moderate CoV, Severe CoV and Critical CoV

Measure: COVID-19 Severity Category

Time: 6 months

No related HPO nodes (Using clinical trials)