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Report for Clinical Trial NCT03211507
Developed by Shray Alag, 2020.
SNP Clinical Trial Gene
Idiopathic Pulmonary Fibrosis Job Exposures Study
A case-control study to investigate whether job exposures are an under-recognized cause of idiopathic pulmonary fibrosis (IPF) using an interview to collect information about previous jobs and a blood test to investigate genetic susceptibility.
NCT03211507 IPF Idiopathic Pulmonary Fibrosis MeSH:Pulmonary Fibrosis Idiopathic Pulmonary Fibrosis Fibrosis
HPO:Pulmonary fibrosis
2 Interventions
Name: Computer-assisted telephone interview
Name: Genetic analysis
Primary Outcomes
Description: estimated using logistic regression for any vs no asbestos exposure and adjusting for age and smoking status
Measure: Association between asbestos exposure and IPF Time: 2 yearsSecondary Outcomes
Description: estimated using logistic regression for categories of cumulative exposure and adjusting for age and smoking status
Measure: Dose-response relationship between asbestos exposure and IPF Time: 2 yearsDescription: MUC5B rs35705950 and asbestos exposure odds ratio.
Measure: Gene-environment interaction (for MUC5B rs35705950 and asbestos exposure) odds ratio. Time: 2 yearsTime Perspective: Prospective
Case-Control
There is one SNP
SNPs
1 rs35705950
Gene-environment interaction (for MUC5B rs35705950 and asbestos exposure) odds ratio.. MUC5B rs35705950 and asbestos exposure odds ratio..