CovidResearchTrials by Shray Alag

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Growth MindsetWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (2)

Name (Synonyms) Correlation
drug1299 Ketotifen 1 MG Wiki 1.00
drug636 Control Wiki 0.38

Correlated MeSH Terms (1)

Name (Synonyms) Correlation
D001943 Breast Neoplasms NIH 0.50

Correlated HPO Terms (1)

Name (Synonyms) Correlation
HP:0003002 Breast carcinoma HPO 0.50

There is one clinical trial.

Clinical Trials

1 Effect of Emotion Mindsets on Emotion Processing: A Multilevel Experimental Investigation

The guiding scientific premise for this research is that a growth emotion mindset will promote more adaptive emotion processing than a fixed emotion mindset. Because emotional sensitivity is particularly salient in adolescent girls, we will focus on this group. Using an experimental design, adolescent girls will be randomly assigned to either a mindset manipulation or a control group (brain education). Each group will complete a 25-minute computer-based lesson followed by a social stressor and a functional magnetic resonance imaging session. Two specific aims will be addressed: (1) to determine whether a growth mindset induction, relative to a control condition, predicts more adaptive emotion processing at the neural, behavioral, and psychological levels of processing; and (2) to determine whether neural processing of emotion accounts for the effect of a growth emotion mindset manipulation on behavioral and psychological processing of emotion. This study builds on a strong empirical database establishing the effect of mindsets on multiple domains of functioning but will be the first to examine the implications of a growth vs. fixed mindset about emotion for emotion processing in adolescent girls, thereby elucidating one specific youth attribute that can support or disrupt emotional development.

NCT03978871 Emotions Behavioral: Growth Mindset Behavioral: Control

Primary Outcomes

Description: Will compare mean change scores across the two conditions (mindset and control) Minimum=1 Maximum=6 High=worse outcome

Measure: Mean Change from Pre to Post Mindset Manipulation on Emotion Mindset Scale (measures beliefs about whether emotions are fixed or malleable)

Time: Pre vs. Post Mindset Manipulation: baseline

Description: Will compare mean change scores across the two conditions (mindset and control) Minimum=1 Maximum=5 High=better outcome

Measure: Mean Change from Pre to Post Mindset Manipulation on Emotional Self-efficacy Scale (measure beliefs about ability to control emotions)

Time: Pre vs. Post Mindset Manipulation: baseline

Description: Will compare mean change scores across the two conditions (mindset and control) Minimum=1 Maximum=5 High=better outcome

Measure: Mean Change from Pre to Post Mindset Manipulation on Emotional Self-efficacy Vignettes (measure beliefs about ability to control emotions in specific situations)

Time: Pre vs. Post Mindset Manipulation: baseline

Description: Will compare mean performance as reflected in reaction time and accuracy across the two conditions (mindset and control)

Measure: Mean Difference in Performance on Go/nogo Task

Time: Post Mindset Manipulation: baseline

Description: Will compare mean levels of self-reported emotion regulation strategies across the two conditions (mindset and control)

Measure: Mean Difference in Emotion Regulation Strategies

Time: Post Mindset Manipulation: baseline

Description: Will compare mean levels of amygdala activation during relevant trials of the Social Evaluation Task and Go/no go Task across the two conditions (mindset and control)

Measure: Mean Difference in Amygdala Activation

Time: Post Mindset Manipulation: baseline

Description: Will compare mean levels of frontal parietal network-amygdala connectivity during relevant trials of the Social Evaluation Task and Go/no go Task across the two conditions (mindset and control)

Measure: Mean Difference in Frontal Parietal Network-Amygdala Connectivity

Time: Post Mindset Manipulation: baseline

Description: Will compare mean change scores across the two conditions (mindset and control)

Measure: Mean Change on Self-Reported State Negative Affect

Time: Pre-Trier vs. Post-Trier: baseline

Secondary Outcomes

Description: Will compare mean change scores across the two conditions (mindset and control)

Measure: Mean Change from Baseline in Emotion Mindset Scores at 2 Months

Time: At baseline and in approximately 2 months

Description: Will compare mean change scores across the two conditions (mindset and control)

Measure: Mean Change from Baseline in Emotion Mindset Scores at 4 Months

Time: At baseline and in approximately 4 months

Description: Will compare mean change scores across the two conditions (mindset and control) Minimum=1 Maximum=5 High=better outcome

Measure: Mean Change from Baseline in Emotional Self-efficacy Scale Scores at 2 Months (measure beliefs about ability to control emotions)

Time: At baseline and in approximately 2 months

Description: Will compare mean change scores across the two conditions (mindset and control) Minimum=1 Maximum=5 High=better outcome

Measure: Mean Change from Baseline in Emotional Self-efficacy Scale Scores at 4 Months (measure beliefs about ability to control emotions)

Time: At baseline and in approximately 4 months

Description: Will compare mean change scores across the two conditions (mindset and control)

Measure: Mean Change from Baseline in Emotional Self-efficacy Vignettes Scores at 2 months

Time: At baseline and in approximately 2 months

Description: Will compare mean change scores across the two conditions (mindset and control)

Measure: Mean Change from Baseline in Emotional Self-efficacy Vignettes Scores at 4 months

Time: At baseline and in approximately 4 months

Description: Will compare mean change scores across the two conditions (mindset and control)

Measure: Mean Change from Baseline in Self-Reported Emotion Regulation Strategies Scores at 2 months

Time: At baseline and in approximately 2 months

Description: Will compare mean change scores across the two conditions (mindset and control)

Measure: Mean Change from Baseline in Self-Reported Emotion Regulation Strategies Scores at 4 months

Time: At baseline and in approximately 4 months

Description: Will compare mean scores during relevant trials of the Social Evaluation Task across the two conditions (mindset and control)

Measure: Mean Difference on Self-Reported State Negative Affect

Time: Post Mindset Manipulation: baseline

Other Outcomes

Description: Will compare mean levels of cingulo-opercular network activation during resting state and relevant trials of the Social Evaluation Task and Go/no go Task across the two conditions (mindset and control)

Measure: Mean Difference in Cingulo-Opercular Network Activation

Time: Post Mindset Manipulation: baseline

Description: Will compare mean levels of cingulo-opercular network-amygdala connectivity during resting state and relevant trials of the Social Evaluation Task and Go/no go Task across the two conditions (mindset and control)

Measure: Mean Difference in Cingulo-Opercular Network-Amygdala Connectivity

Time: Post Mindset Manipulation: baseline

Description: Will conduct exploratory whole-brain analyses comparing activation patterns during resting state and relevant trials of the Social Evaluation Task and Go/no go Task across the two conditions (mindset and control)

Measure: Group Differences for Whole-Brain Analyses

Time: Post Mindset Manipulation: baseline

Description: Will compare mean change scores across the two conditions (mindset and control)

Measure: Mean Change from Baseline in Depressive Symptoms Scores at 2 months

Time: At baseline and in approximately 2 months

Description: Will compare mean change scores across the two conditions (mindset and control)

Measure: Mean Change from Baseline in Depressive Symptoms Scores at 4 months

Time: At baseline and in approximately 4 months

Description: Will compare mean change scores across the two conditions (mindset and control)

Measure: Mean Change from Baseline in Anxiety Symptoms Scores at 2 months

Time: At baseline and in approximately 2 months

Description: Will compare mean change scores across the two conditions (mindset and control)

Measure: Mean Change from Baseline in Anxiety Symptoms Scores at 4 months

Time: At baseline and in approximately 4 months

No related HPO nodes (Using clinical trials)