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CTUS examinationWiki

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Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


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Name (Synonyms) Correlation

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D012128 Respiratory Distress Syndrome, Adult NIH 0.09

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Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 WeanINg From Mechanical Ventilation for ARDS CovId-19 Patients Guided by Combined Thoracic UltraSound: a Prospective, Multicenter, Randomized, Open-label, Parallel-group Clinical Trial

The most feared complication of COVID-19 infection is the occurrence of an acute respiratory distress syndrome (ARDS) that requires ICU admission and prolonged mechanical ventilation in more than 2% of the affected patients. Establishing the correct time to extubate mechanically ventilated patients is a crucial issue in the critical care practice. Delayed extubation has several consequences such as patient's mortality, health-care-related complications, neuropsychological adverse events. The aim of the INVICTUS study is to evaluate whether a CTUS-based MV weaning strategy could reduce the duration of mechanical ventilation of ARDS COVID-19 ICU patients by 72 hours, compared with usual medical care.

NCT04372680 COVID-19 ARDS, Human Mechanical Ventilation Diagnostic Test: CTUS examination
MeSH:Respiratory Distress Syndrome, Adult

Primary Outcomes

Description: Delay from the start of MV weaning process (day of the switch from volume control mode to pressure support ventilation) to extubation (or spontaneously breathing through tracheostomy cannula) for at least 48h, as previously defined.

Measure: Delay from the start of Mechanical Ventilation weaning process to extubation

Time: day 28

Secondary Outcomes

Description: delay from intubation to extubation

Measure: delay from intubation to extubation

Time: day 28

Description: Successful of extubation if patient is not reintubated after 48 hours of extubation

Measure: Successful of extubation

Time: day 28

Description: mortality rate

Measure: mortality rate

Time: day 28


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