CovidResearchTrials by Shray Alag


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Susceptibility to infectionWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (0)


Name (Synonyms) Correlation

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D004198 Disease Susceptibility NIH 0.45

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Differences in Susceptibility to SARS CoV-2 Infection According to ACE2 and CD26 Receptors, Specific CD4/CD8 T Cell Response to Viral Peptides, and KIR Receptors Among Health Care Workers Highly Exposed to Patients With COVID-19 Diagnosis.

The primary objective of this study is to establish differences in susceptibility to SARS CoV-2 infection among health care workers (HCW) highly exposed to patients with COVID-19 diagnosis. To ascertain this issue, we evaluated: - Changes in receptor polymorphism (ACE2 and CD26 receptor study. - SARS-CoV-2 CD4/CD8 T cell response (CTL) - Different KIR phenotypes

NCT04402827 Health Care Worker Patient Transmission Receptor Site Alteration Susceptibility, Disease Immune Response Diagnostic Test: Susceptibility to infection
MeSH:Disease Susceptibility

Primary Outcomes

Description: ACE2 analysis

Measure: Susceptibility to SARS CoV-2 infection according to ACE2 receptor

Time: 1 month

Description: Activation of CD4-CD8 by viral peptides

Measure: Cellular immune response to SARS CoV-2 infection

Time: 1 month

Description: Analysis of KIR in NK cells

Measure: Susceptibility to infections according to KIR phenoytpes

Time: 2 months

Secondary Outcomes

Description: Survey

Measure: Characteristics of exposure in time and intensity of HCW with SARS CoV-2 infection

Time: 1 month

Description: Activation of CD4-CD8 by viral peptides

Measure: Cellular immune response in HCW with positive IgG against SARS CoV-2

Time: 1 month


No related HPO nodes (Using clinical trials)