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drug1450 | Medical Mask Wiki | 1.00 |
drug1545 | N95 respirator Wiki | 1.00 |
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There is one clinical trial.
Coronavirus Disease 2019 (COVID-19) is spreading worldwide and has become a public health emergency of major international concern. Currently, no specific drugs or vaccines are available. For severe cases, it was found that aberrant pathogenic T cells and inflammatory monocytes are rapidly activated and then producing a large number of cytokines and inducing an inflammatory storm. Mesenchymal stem cells (MSCs) have been shown to possess a comprehensive powerful immunomodulatory function. This study aims to investigate the safety and efficacy of intravenous infusion of mesenchymal stem cells in severe patients with COVID-19.
Description: Assessment of Overall survival at 30 days post intervention
Measure: Overall survival Time: 60 daysDescription: To assess the anti-inflammatory effect of the proposed treatment with assessment of the levels of C-reactive protein (mg/dL)
Measure: Changes on inflammatory C-reactive protein Time: 60 daysDescription: days of the patients in hospital
Measure: Hospital stay Time: 60 daysDescription: Evaluation of functional respiratory changes: PaO2 / FiO2 ratio
Measure: Oxygenation index (PaO2/FiO2) Time: 60 daysDescription: Improvement in Liao's score (2020)
Measure: Improvement in Liao's score (2020) Time: 60 daysDescription: Computed tomography Chest assesment will be done to assess improvement in radiological findings of COVID-19
Measure: Radiological improvement Time: 60 daysDescription: PCR testing to check PCR negativity
Measure: Time of COVID19 PCR negativity Time: 28 days