CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Canakinumab Injection 600mgWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (3)


Name (Synonyms) Correlation
drug1519 Montelukast Oral Granules Wiki 1.00
drug516 Canakinumab Injection 300mg Wiki 1.00
drug1860 Placebos Wiki 0.24

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D001249 Asthma NIH 0.50

Correlated HPO Terms (1)


Name (Synonyms) Correlation
HP:0002099 Asthma HPO 0.50

There is one clinical trial.

Clinical Trials


1 Canakinumab to Reduce Deterioration of Cardiac and Respiratory Function in SARSCoV2 Associated Acute Myocardial Injury With Heightened Inflammation

TThe purpose of this prospective, Phase 2, single center, blinded, randomized controlled study is to demonstrate as a proof of concept that early treatment with canakinumab prevents progressive heart and respiratory failure in patients with COVID-19 infection. These results will lead to and inform a Phase III randomized placebo-controlled trial.

NCT04365153 COVID-19 SARS-CoV 2 Drug: Canakinumab Injection 600mg Drug: Canakinumab Injection 300mg Drug: Placebos

Primary Outcomes

Description: Number of days

Measure: Time to clinical improvement up to day 14, defined as the time in days from randomization to either an improvement of two points on a seven-category ordinal scale or discharge from the hospital, whichever occurs first.

Time: Up to day 14

Secondary Outcomes

Description: Number of days

Measure: Mortality at day 28

Time: Up to day 28


No related HPO nodes (Using clinical trials)