CovidResearchTrials by Shray Alag

CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)

1DWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)

Name (Synonyms) Correlation
drug40 3D Wiki 1.00

Correlated MeSH Terms (1)

Name (Synonyms) Correlation
D020521 Stroke NIH 0.32

Correlated HPO Terms (1)

Name (Synonyms) Correlation
HP:0001297 Stroke HPO 0.32

There is one clinical trial.

Clinical Trials

1 Novel Training Environment to Normalize Altered Finger Force Direction Post Stroke

Despite the functional importance, fingertip forces are rarely explicitly addressed with feedback in therapy. This gap in treatment is due to a lack of tools to provide explicit feedback on patients' volitional finger force generation. To address this unmet need, the investigators developed a novel tool for practice of volitional three-dimensional (3D) force generation with explicit feedback. The objective of this project is to determine if 3D finger force training is an effective tool in restoring hand function post stroke.

NCT03995069 Stroke Behavioral: 3D Behavioral: 1D
MeSH:Stroke
HPO:Stroke

Primary Outcomes

Description: a clinical assessment for upper extremity function

Measure: Action Research Arm Test (ARAT)

Time: 3rd baseline to within 1 week post intervention

Other Outcomes

Description: a clinical assessment for upper extremity function.

Measure: Box and Block Test

Time: 3rd baseline to within 1 week post intervention

Description: Angular deviation of the grip force vector from the target direction

Measure: Force Direction

Time: 3rd baseline to within 1 week post intervention

Description: a clinical assessment for upper extremity function

Measure: Action Research Arm Test

Time: 3rd baseline to 1 month post intervention

Description: a clinical assessment for upper extremity function.

Measure: Box and Block Test

Time: 3rd baseline to 1 month post intervention

Related HPO nodes (Using clinical trials)

HP:0001297: Stroke
Genes 174
TANGO2 JAG1 SMARCAL1 LIMK1 MMUT RFC2 VHL TREX1 PCNT ENG JAK2 TTR CCM2 COX2 COX1 TRNF GTF2I KRAS CPS1 GDF2 SMAD3 TET2 TRNW ABCC6 MFAP5 TGFBR3 APP ELN ADA2 TRNF OTC LMNA LOX FLNA GATA6 CLIP2 ELN XYLT1 APP PNP THPO GNAQ ADA2 SH2B3 TRNC GYS1 F2 SCN5A GATA4 TGFB3 SNAP29 HBB GLA SMAD4 NPPA TRNS2 COL4A1 ACVRL1 TRNK TRNL1 ND1 ND4 TNNT2 KCNQ1 FBN1 COX1 ACVRL1 AGXT COL3A1 TGFBR1 MYPN TGFB2 TRNW APP ALOX5AP PRNP COX3 TRNQ ND5 RFT1 TP53 XYLT2 MYH11 MPL CALR MYBPC3 MECP2 ND6 CST3 CYTB ACTA2 MYD88 ND5 F5 ENG ELN CYTB SMAD4 TRNV SLC2A10 PRKG1 MLXIPL GUCY1A1 HTRA1 TBL2 COX3 MTHFR PRKCH PRKAG2 NR3C1 TREX1 SLC19A2 PIK3C2A APP NR2F2 ZAP70 TGFBR2 WFS1 GLA MYLK APP NOTCH3 TRNS1 COX2 TPP2 COL4A1 KIF20A CBS BAZ1B TRNS2 ANGPTL6 TNXB TRNQ MPL ENG MAT2A JAK2 ZMPSTE24 ASS1 CYP11B1 TET2 SMAD4 MPL TNNI3 ACAD9 ND6 TRNS1 STIM1 HSD11B2 SLC19A2 DYRK1B PMM2 FLNC GTF2IRD1 SON ACTG1 FOXE3 TRNL1 THSD1 NOS3 GUCY1A1 MYH11 ACTB TRNH NAGS HTRA1 PIGA CST3 MYH11 COL3A1 ND1 JAK2 DPM3 CRELD1
Protein Mutations 10
A143T C807T G20210A I843S L33P M235T N215S R112H V34L V66M
SNP 5
rs10033464 rs1906591 rs2106261 rs333 rs6265