CovidResearchTrials by Shray Alag

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Gait RetrainingWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)

Name (Synonyms) Correlation
drug636 Control Wiki 0.38

Correlated MeSH Terms (1)

Name (Synonyms) Correlation
D020370 Osteoarthritis, Knee NIH 0.58

Correlated HPO Terms (1)

Name (Synonyms) Correlation
HP:0005086 Knee osteoarthritis HPO 0.58

There is one clinical trial.

Clinical Trials

1 Effectiveness of a Walking Intervention on Impact Loading and Pain

This study investigates the feasibility of a gait-retraining program for older adults with knee osteoarthritis. The study will enroll 40 participants, with 20 receiving a gait retraining intervention and 20 receiving a graded walking program without gait retraining.

NCT04148807 Osteoarthritis, Knee Knee Pain Chronic Behavioral: Gait Retraining Behavioral: Control
MeSH:Osteoarthritis, Knee
HPO:Knee osteoarthritis

Primary Outcomes

Description: # of participants screened per month

Measure: Recruitment rate

Time: through study completion, an average of 2 years

Description: # of participants enrolled per month

Measure: Enrollment rate

Time: through study completion, an average of 2 years

Description: % participants that complete all study visits

Measure: Retention

Time: through study completion, an average of 2 years

Secondary Outcomes

Description: Proportion of participants who withdraw or terminated by investigators and reasons why

Measure: Withdrawals/Terminated

Time: through study completion, an average of 2 years

Description: Proportion of participants with AE/UP

Measure: Adverse events (AE)/Unanticipated problems (UP)

Time: through study completion, an average of 2 years

Description: Slope of the most linear portion of the vertical ground reaction force curve, during early stance.

Measure: Vertical average loading rate

Time: Change from baseline to conclusion of intervention, an average of 1-month

Description: Maximum slope of the most vertical portion of the vertical ground reaction force curve between successive data points, during early stance.

Measure: Vertical instantaneous loading rate

Time: Change from baseline to conclusion of intervention, an average of 1-month

Description: WOMAC questionnaire, pain sub scale 0-20

Measure: Knee Pain with Activities

Time: Change from baseline to conclusion of intervention, an average of 1-month

Description: Visual analog scale, 0-100

Measure: Knee Pain Severity

Time: Change from baseline to conclusion of intervention, an average of 1-month

Description: Assessed using hand held algometer

Measure: Pressure pain threshold

Time: Change from baseline to conclusion of intervention, an average of 1-month

Related HPO nodes (Using clinical trials)

HP:0005086: Knee osteoarthritis
Genes 4
COL9A2 SMAD3 SMAD3 COL2A1
Protein Mutations 2
Q28D T20S
SNP 0