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Povidone-iodineWiki

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Correlated Drug Terms (2)


Name (Synonyms) Correlation
drug1086 Hydroxychloroquine Wiki 0.10
drug1822 Placebo Wiki 0.06

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D018352 Coronavirus Infections NIH 0.04

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 The Efficacy of Topical Povidone-Iodine Rinses in the Management of the Coronavirus Disease 2019 (COVID-19)

The aim of this study is to determine if Povidone iodine (PVP-I) rinses and throat gargles or a PVP-I gel forming nasal spray compared to a placebo (a treatment that has no physical effect to a person) is an effective treatment for patients diagnosed with COVID-19. These patients have been diagnosed with mild/moderate COVID-19 symptoms and sent home for self-isolation. Patients will be instructed to take either of the two treatments or placebo twice daily for two weeks and have follow up visits 2 and 4 weeks after. The participants will also complete study related procedures such as saliva sample collection, and two questionnaires throughout the study period. The investigators hypothesize that COVID 19 positive participants who use either of the Povidone - Iodine treatment will have a reduction in their viral load, develop a negative oral mucosa sample and improve their clinical symptoms.

NCT04449965 Covid19 Drug: Povidone-iodine Drug: Placebo

Primary Outcomes

Description: A saliva sample will be analyzed to monitor the duration of positivity and when test becomes negative for SARS-CoV-2.

Measure: Change in SARS-CoV-2 positivity in the saliva

Time: A saliva sample will be taken every 2 days for 2 weeks, and again at 4 and 6 weeks

Description: Quantify the amount of SAR-CoV-2 viral load present in the saliva.

Measure: Change in the SAR-CoV-2 viral load in the saliva

Time: A saliva sample will be taken every 2 days for 2 weeks, and again at 4 and 6 weeks

Secondary Outcomes

Description: This is a 44 question, quality of life survey designed to measure different aspects affected by the common cold.

Measure: Change in Wisconsin Upper Respiratory Symptom Survey (WURSS-44)

Time: daily for 2 weeks, 4 weeks, and 6 weeks

Description: That includes 22 questions about symptoms and social/emotional consequences of your nasal disorder.

Measure: Change Sino nasal Outcome Test (SNOT-22)

Time: baseline, 2 weeks, 4 weeks, 6 weeks

Description: We will record and worsening of clinical condition such as, need for hospitalization/oxygen support.

Measure: Change in clinical condition

Time: daily for 2 weeks, 4 weeks, and 6 weeks


No related HPO nodes (Using clinical trials)