There is one clinical trial.
Predi-COVID is a prospective cohort study composed of people positively tested for COVID-19 in Luxembourg, followed digitally for monitoring participants' health evolution and symptoms at home. Participants will be actively followed for 14 days from the time of confirmation of diagnosis, whether they are at the hospital or at home in isolation or quarantine. Short evaluations will be also performed at week 3 and week 4 and then monthly for a period up to 12 months to assess potential long term consequences of COVID-19. A subsample of 200 participants will be contacted to integrate complementary clinical data and collect samples. The study aims at identifying factors associated with the COVID-19 disease severity. COVID-19 patients with severity criteria will be compared to patients with mild disease managed at home. A deep phenotyping related to the symptoms of the disease as well as biosampling allowing for laboratory-based and computational analytics will be performed.
Description: Number of symptoms associated with Covid-19
Measure: Description of clinical manifestations Time: 1 yearDescription: Number of hospitalizations
Measure: Clinical aggravation of the infection Time: 1 yearDescription: Number of discharges
Measure: Discharge of hospitalization Time: 1 yearDescription: Number of deaths
Measure: Death Time: 1 yearDescription: Whole blood count parameters
Measure: Description of biological manifestations Time: 1 yearDescription: Plasma cytokine levels
Measure: Description of biological manifestations Time: 1 yearDescription: Antibodies to SARS-Cov2
Measure: Description of biological manifestations Time: 1 yearDescription: HLA genotypes
Measure: Patient-related prognostic factors Time: 1 yearDescription: Coinfections
Measure: Patient-related prognostic factors Time: 1 yearDescription: Virus mutations
Measure: Virus-related prognostic factors Time: 1 yearDescription: Audio feature extracted from 30 seconds recordings of participants' voice reading a prespecified text, collected throughout the CoLIVE LIH smartphone app.
Measure: Vocal biomarker of Covid-19 related respiratory complications Time: 1 year