CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


HCQ & AZWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (3)


Name (Synonyms) Correlation
drug563 Chloroquine Sulfate Wiki 0.71
drug1103 Hydroxychloroquine Sulfate Wiki 0.28
drug262 Azithromycin Wiki 0.17

Correlated MeSH Terms (4)


Name (Synonyms) Correlation
D003141 Communicable Diseases NIH 0.09
D007239 Infection NIH 0.06
D045169 Severe Acute Respiratory Syndrome NIH 0.05
D018352 Coronavirus Infections NIH 0.04

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 A Multicenter, Open-label, Pilot Study on Using Hydroxychloroquine (HCQ) and Azithromycin (AZ) Prophylaxis for Healthcare Workers With a Potential Risk of Exposure to COVID-19 Patients

The main objective of this study is to assess the efficacy of the combination hydroxychloroquine and Azithromycin (HCQ and AZ) in reducing the infection risk among health care professionals in direct contact with COVID-19 patients.

NCT04354597 COVID-19 Drug: HCQ & AZ

Primary Outcomes

Description: Compare the proportion of participants who have RT-PCR confirmed infection with SARS-CoV-2 in both arms during the study period, measured by negative PCR test for SARS COV-2 virus

Measure: Effect of HCQ and AZ in preventing infection with COVID-19 among healthcare workers working with COVID-19 patients

Time: 4 Months

Secondary Outcomes

Description: Solicited and unsolicited adverse events in participants receiving HCQ+AZ during the study period, measured by the incidence of AEs in both arms. (The difference in type, number, and intensity)

Measure: Safety of HCQ and AZ

Time: 4 Months

Description: The proportion of participants who require oxygen therapy for any indication during the study period in both arms, measured by the requirement for O2 or not in both arms.

Measure: Oxygen requirement

Time: 4 Months

Description: The proportion of participants who need ICU admission for any reason during the study period in both arms, measured by the incidence of ICU admission in both arms.

Measure: ICU admission

Time: 4 Months

Description: The proportion of participants who die of any cause during the study period in both arms, measured by the incidence of death in both arms.

Measure: Mortality rate

Time: 4 Months


No related HPO nodes (Using clinical trials)