CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Neutral writing controlWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (3)


Name (Synonyms) Correlation
drug79 ASC09/ritonavir group Wiki 1.00
drug2872 lopinavir/ritonavir group Wiki 1.00
drug1332 Let It Out (LIO)-C Wiki 1.00

Correlated MeSH Terms (2)


Name (Synonyms) Correlation
D045169 Severe Acute Respiratory Syndrome NIH 0.05
D018352 Coronavirus Infections NIH 0.04

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Let It Out (LIO) and COVID19: a Randomised Controlled Trial of an Online Emotional Disclosure-based Intervention for Adults During the COVID19 Pandemic

A randomised controlled trial designed to test whether an online expressive writing intervention (LIO-C) can reduce distress for English-speaking adults during the global COVID19 pandemic. Hypothesis: LIO-C will improve distress (as measured by K10) in adults at 1 week post-intervention compared to a neutral writing control during the COVID19 pandemic.

NCT04386668 COVID19 Other: Let It Out (LIO)-C Other: Neutral writing control

Primary Outcomes

Description: 10-item self-report distress scale

Measure: Kessler Psychological Distress Scale (K10)

Time: 1 week post-intervention

Secondary Outcomes

Description: 10-item self-report distress scale

Measure: Kessler Psychological Distress Scale (K10)

Time: Immediately and 8 weeks post-intervention

Description: Self-report stress scale

Measure: Perceived Stress Scale (PSS-10)

Time: Immediately, 1 week and 8 weeks post-intervention

Description: Self-report sleep scale

Measure: Pittsburgh Sleep Quality Index (PSQI)

Time: Immediately, 1 week and 8 weeks post-intervention

Description: Self-report self-compassion scale

Measure: Self-compassion scale (SCS)

Time: Immediately, 1 week and 8 weeks post-intervention

Description: Self-report loneliness scale

Measure: UCLA Loneliness Scale (UCLA LS)

Time: Immediately, 1 week and 8 weeks post-intervention

Description: Self-report measure of MHS usage

Measure: Uptake of existing mental health services (MHS)

Time: Immediately, 1 week and 8 weeks post-intervention

Description: 3-item, 7-point, Likert scale measuring how personal and meaningful participants' felt their writing was and their mood

Measure: Mood and meaning

Time: Immediately after each writing session

Description: Via an online feedback form

Measure: Acceptability

Time: Immediately post-intervention


No related HPO nodes (Using clinical trials)